Patterns of neurological deficits in COVID-19 infections: a literature review

Murad Mohammed Ali Alghanmi, Salman Talal Wahboo, Hussain Hassan Al Rashdi, Adel Abdulrahman Alotaibi, Yaser Saeed Alqahtani, Sultan Sameer Alrabghi, Ahmed Ibrahim Almania, Hadeel khalid Elshahti, Abdullah Mohammed Alluhaidah, Mohammed Ali Alshehri, Yaser Amer Alkasih


Neurologic deficits accompanying SARS-CoV-2 infections are associated with high mortality and morbidity. However, the exact prevalence and underlying pathogenesis of each disease are still unknown and under investigated. That is why this review reports the latest neurologic disorders diagnosed in COVID-19 patients and the possible underlying pathogenesis. We searched PubMed, Medline, Web of science, Embase, Google scholar, and Scopus using the following search terms; severe acute respiratory syndrome of coronavirus-2 or SARS-CoV-2 or COVID-19 or coronavirus and brain or nerve or neuro. Only studies that reported any neurologic deficits accompanying the COVID-19 diagnosis were included. COVID-19 patients had a wide range of neurologic deficits affecting different parts of the nervous systems. Cerebrovascular disorders, seizures, and cranial nerve diseases were reported in many cases. Autoimmune neuropathy was also reported in many patients. The incidence of neurologic deficits was considered high in COVID-19 patients and was associated with high morbidity and mortality.


COVID-19, Neurological deficits, Mortality

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