A cross sectional study on factors influencing non-adherence to treatment among paediatric tuberculosis patients in field practice area of Osmania Medical College, Hyderabad

Authors

  • Sreelatha Panuganti Department of Community Medicine, Osmania Medical College, Koti, Hyderabad, India
  • Kenche Bhavani Department of Community Medicine, Osmania Medical College, Koti, Hyderabad, India
  • L. Vijayasree Department of Community Medicine, Osmania Medical College, Koti, Hyderabad, India
  • Ananda Krishna Department of Community Medicine, Osmania Medical College, Koti, Hyderabad, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20221327

Keywords:

Tuberculosis, Adherence, Paediatric TB, DOTS, Anti-tuberculosis treatment

Abstract

Background: Tuberculosis (TB) remains to be a major burden in India. Treatment adherence is a key factor in the outcome of therapy. Non-adherence may also result in acquired drug resistance. This study has been one of the very few research endeavours to identify factors associated with non-adherence to TB treatment among paediatric patients in Hyderabad. The objectives are to determine the factors influencing non-adherence to treatment among paediatric TB patients and to study the role of sociodemographic factors in non-adherence to treatment.

Methods: A cross sectional study was conducted between June 2021 to September 2021 among paediatric TB patients ≤18 years old who were on anti-TB treatment in field practice area of Osmania Medical College, Hyderabad. By using convenient sampling method, a sample size of 150 has been taken. Data was collected using a pretested semi structured questionnaire. Data was entered into Microsoft excel and analysed using Epi Info version 7.2.2.6 and frequencies, proportions, and Chi square tests used.

Results: Among the 150 paediatric TB patients, majority 56.2% of the patients belong to male gender. Non-adherent to anti-tuberculosis treatment were 18%. In this, 10% belongs to younger age (<5 years), 4% females, 14% males, 13.3% rural residence, 4.7% urban residency, 14% were having side effects. The presence of side effects to anti-tubercular is the main influencing factors for non-adherence to treatment.

Conclusions: The identification of various factors could help in increasing the knowledge about TB and in taking measures to cope-up with side effects to anti-tubercular medications which is required to improve treatment adherence.

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References

World health Organization Tuberculosis and air travel: Guidelines for prevention and control. World Health Organization, Geneva. Available at: http://apps.who.int/iris/bitstream/handle/10665/43921/9789241547505_eng.pdf?sequence=1. Accessed on 10 December 2021.

World health Organization Definitions and reporting framework for tuberculosis 2013 revision. Available at: https://apps.who.int/iris/handle/10665/79199. Accessed on 10 December 2021.

World health Organization factsheet on Tuberculosis. 2020. Available at: https://www.who.int/news-room/fact-sheets/detail/tuberculosis. Accessed on 10 December 2021.

Islam MM, Borgohain A. A study on treatment compliance of patients under revised national tuberculosis control programme in Jorhat district of assam. Indian J Appl Res. 2018;8.

Fekadu G, Bekele F, Bekele K, Girma T, Mosisa G, Gebre M, Alemu T, Tekle T, Gamachu B, Diriba A. Adherence to Anti-Tuberculosis Treatment Among Pediatric Patients at Nekemte Specialized Hospital, Western Ethiopia. Patient Prefer Adherence. 2020;14:1259-65.

Bagchi S, Ambe G, Sathiakumar N. Determinants of Poor Adherence to Anti-Tuberculosis Treatment in Mumbai, India. Int J Prev Med. 2010;1:223-32.

Santos JC, Silva JB, Rangel MA, Barbosa L, Carvalho I. Preventive therapy compliance in paediatric tuberculosis - A single centre experience. Pulmonology. 2020;26(2):78-83.

Chang S-H, Eitzman S, Nahid P, Finelli M. Factors associated with failure to complete isoniazid therapy for latent tuberculosis infection in children and adolescents. J Infect Public Health. 2013;7.

Laghari M, Talpur BA, Sulaiman SAS, Khan AH, Bhatti Z. Assessment of adherence to anti-tuberculosis treatment and predictors for non-adherence among the caregivers of children with tuberculosis. Transactions of The Royal Society of Tropical Medicine and Hygiene. 2021;115(8):904-13.

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Published

2022-05-27

How to Cite

Panuganti, S., Bhavani, K., Vijayasree, L., & Krishna, A. (2022). A cross sectional study on factors influencing non-adherence to treatment among paediatric tuberculosis patients in field practice area of Osmania Medical College, Hyderabad. International Journal Of Community Medicine And Public Health, 9(6), 2479–2482. https://doi.org/10.18203/2394-6040.ijcmph20221327

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Original Research Articles