Inherited bowel cancer: a review from a surgeon’s perspective


  • Mirza Faraz Saeed General and Colorectal Surgery, King Hamad University Hospital, Bahrain
  • Basel Maher Ebrahim General Surgery, King Hamad University Hospital, Bahrain
  • Sara Salah Khairi General Surgery, King Hamad University Hospital, Bahrain
  • Roshan George Varkey General Surgery, King Hamad University Hospital, Bahrain
  • Isam Mazin Juma General and Colorectal Surgery, King Hamad University Hospital, Bahrain



Neoplastic and non-neoplastic polyps, PJS, JPS, CS, LS, FAP


Colorectal cancer (CRC) is the second most deadly cancer affecting globally. Although most CRCs seen in young adults are sporadic, hereditary cancer syndromes should be considered as an essential factor. Screening for colorectal cancer aids in the early detection and treatment of early-stage CRC; which reduces mortality rates. This review article aimed to present neoplastic and non-neoplastic polyps and their management from a surgeon's perspective while describing screening protocols in high-risk groups. It also highlighted the etiology, clinical features, diagnosis and management of adenomatous polyps and hereditary bowel cancer syndromes like Peutz-Jeghers syndrome (PJS), juvenile polyposis syndrome (JPS), Cowden syndrome (CS), Lynch syndrome (LS) and familial adenomatous polyposis (FAP). The article summarized the importance of these syndromes as a risk factor in colorectal cancer and identifies these as high-risk group patients in colorectal screening protocols. A summary of the management of these risk factors has been described from a surgeon's point of view.

Author Biographies

Mirza Faraz Saeed, General and Colorectal Surgery, King Hamad University Hospital, Bahrain

Specialist General and Colorectal Surgeon, King Hamad University Hospital, Bahrain

Basel Maher Ebrahim, General Surgery, King Hamad University Hospital, Bahrain

General Surgery Department 
Senior House Officer

Sara Salah Khairi, General Surgery, King Hamad University Hospital, Bahrain

General Surgery Department 
Senior House Officer

Roshan George Varkey, General Surgery, King Hamad University Hospital, Bahrain

Registrar General Surgery, King Hamad University Hospital, Bahrain

Isam Mazin Juma, General and Colorectal Surgery, King Hamad University Hospital, Bahrain

Consultant General and Colorectal Surgeon, King Hamad University Hospital, Bahrain


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How to Cite

Saeed, M. F., Ebrahim, B. M., Khairi, S. S., Varkey, R. G., & Juma, I. M. (2022). Inherited bowel cancer: a review from a surgeon’s perspective. International Journal Of Community Medicine And Public Health, 9(6), 2709–2717.



Review Articles