DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20220831

Epidemiological profile of patients with urolithiasis in a tertiary care center of Eastern Nepal: a retrospective cross-sectional study

Nimesh Lageju, Durga Neupane, Awaj Kafle, Harsh Kumar

Abstract


Background: This study is aimed to estimate descriptive statistics of socio-demographic and clinical profile of patients with urolithiasis visiting urology division, Department of Surgery of BPKIHS.

Methods: This is a retrospective study. A total of 409 patients diagnosed with urolithiasis admitted to BPKIHS from January to December 2017 were included. The hospital medical records of patients were reviewed using a Pro forma to record the epidemiological data. The data was entered into the Microsoft Excel software and analyzed using statistical package for social studies (SPSS) software 23.0 version.

Results: The peak age group of the high burden of urolithiasis observed was 20-30 years (27.1%) with the mean age plus standard deviation of the patients being 39.60±15.67 years. Among them, 54% were male and 46% were female with a ratio of 1.17:1. The most common site of urolithiasis was the ureter (44.1%) and kidney (39.3%). 11% of patients had stones on more than one site.

Conclusions: It is concluded that the highest prevalence of urolithiasis is in the age group 20-30 years with male predominance and the common site being ureter. Further studies are needed as other factors affecting this disease are yet to be studied.

 


Keywords


Urolithiasis, Calcium oxalate, Cysteine, Uric acid, Prevalence

Full Text:

PDF

References


Smith Y. 2016. What is urolithiasis? News medical life science. Available at: https://www.news-medical.net/health/What-is-Urolithiasis.aspx. Accessed on 04 May 2018.

Chataut C. Kidney stones. Nirogi Nepal. 2017. Available at: http://niroginepal.com/en/disease/ kidney-urinary-stone/. Accessed on 04 May 20218.

Muslumanoglu AY, Binbay M, Yuruk E, Akman T, Tepeler A, Esen T et al. Updated epidemiologic. study of urolithiasis in Turkey. I: Changing characteristics of urolithiasis. Urol Res. 2011;39(4):309-14.

Alpers CE, Chang A. The Kidney: Urolithiasis (Renal Calculi, Stones). In: Kumar V, Abbas AK, Aster JC. Robbins & Cotran Pathologic Basis of Disease. South Asian edition. Elsevier. 2015;2:951-2.

Lee YH, Huang WC, Tsai JY, Lu CM, Chen WC, Lee MH et al. Epidemiological studies on the prevalence of upper urinary calculi in Taiwan. Urol Int. 2002;68(3):172-7.

Atan L, Andreoni C, Ortiz V, Silva EK, Pitta R, Atan F et al. High kidney stone risk in men working in steel industry at hot temperatures. Urology. 2002;65(5):858-61.

Rodgers A. Race, ethnicity and urolithiasis: a critical review. Urolithiasis. 2013 Apr 1;41(2):99-103.

Cook J, Lamb BW, Lettin JE, Graham SJ. The epidemiology of urolithiasis in an ethnically diverse population living in the same area. Urol J. 2016;13(4):2754-8.

Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC. Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney Int. 2003;63(5):1817-23.

Shrestha SM, Shrestha S, Bahadur S. Incidence of urolithiasis In Bir Hospital. Journal of Nepal Medical Association. 1971;9(4):201-6.

Ketabchi AA, Aziziolahi GA. Prevalence of symptomatic urinary calculi in Kerman, Iran. Urol J. 2008;5(3):156-60.

Yu DS, Yang YT, Lai CH. Epidemiology and treatment of inpatients urolithiasis in Taiwan. Formosan Journal of Surgery. 2016;49:136-41.

Sreedharan J, John L, Aly FH, Mutappallymyalil J. Urolithiasis in male patients: A pilot study on the ethnic differences and clinical profile. Nepal J Epidemiol. 2014;4(4):393-8.

Ahmad S, Ansari TM, Shad MA. Prevalence of renal calculi: type, age and gender specific in southern Punjab, Pakistan. Professional Medical Journal. 2016;23(4):389-95.

Knoll T. Epidemiology, pathogenesis and pathophysiology of urolithiasis. European Urology Supplements. 2010;9(12):802-6.

Chand R, Shah A, Pant D, Paudel S. Common site of urinary calculi in kidney, ureter and bladder region. Nepal Med Coll J. 2013;15(1):5-7.

Lallas CD, Liu XS, Chiura AN, Das AK, Bagley DH. Urolithiasis location and size and the association with microhematuria and stone-related symptoms. J Endourol. 2011;25(12):1909-13.

Fan J, Chandhoke PS, Grampes SA. Role of Sex Hormones in Experimental Calcium Oxalate Nephrolithiasis. J Am Soc Nephrol. 1999;10:376-80.