Published: 2021-10-27

A trend analysis of people living with human immunodeficiency virus attending an anti-retroviral therapy centre in urban Bangalore

Ramesh Masthi N. R., Divya Bharathi G., Pruthvi S.


Background: HIV infection in India is a major public health problem. The anti-retroviral therapy (ART) centre is the backbone of the national acquired immune deficiency syndrome (AIDS) control program (NACO). To assess the trend of new people living with human immunodeficiency virus (PLHIV) registered at an ART centre in Bangalore and their treatment status.

Methods: All the PLHIV registered at an ART centre from 1st January, 2009 to 31st December, 2018 were included in the study. PLHIV registered but not initiated on treatment, were excluded.

Results: Out of 4428 PLHIV registered at an ART centre, 2964 were initiated on treatment. The youngest PLHIV registered was 6 years, oldest was 79 years and the decadal median age was 38 years. Majority (41.4%) were in the age group of 31 to 40 years. Predominant gender was male. A declining trend of new PLHIV, LFU/stopped/missed cases over the past decade was observed. The 1658 are alive, 402 died, 305 cases either missed, stopped or lost to follow up, 32 cases were opted out of the treatment and 567 cases were transferred out.

Conclusions: A decline in number of new PLHIV, LFU, missed and stopped over the decade was observed.


HIV, Trend, PLHIV, ART centre, NACO

Full Text:



National Strategic Plan for HIV/AIDS and STI 2017-2024. Available at: Accessed on 24 January 2021.

World Health Organisation. Available at: Accessed on 24 January 2021.

National AIDS Control Organization (NACO). Technical Report: 2018. Available at: Accessed on 2021 January 24.

Annual report 2017-2018. Available at: Accessed on 2021 January 24.

Patient Monitoring Guidelines for HIV Care and Anti-Retroviral Therapy. Available at: Accessed on 24 January 2021.

Gesesew HA, Ward P, Woldemichael K, Mwanri L. Prevalence, trend and risk factors for anti-retroviral therapy discontinuation among HIV-infected adults in Ethiopia in 2003-2015. PLoS ONE. 2017;12(6):e0179533.

National AIDS Control Organisation and ICMR-National Institute of Medical Statistics. HIV Estimations 2017: Technical Report. New Delhi: NACO, Ministry of Health and Family Welfare, Government of India. 2018.

Granich R, Gupta S, Hersh B, Williams B, Montaner J. Trends in AIDS Deaths, New Infections and ART Coverage in the Top 30 Countries with the Highest AIDS Mortality Burden; 1990-2013. PLOS ONE. 2015;10(7):e0131353.

Swendeman D, Fehrenbacher AE, Roy S, Das R, Ray P, Sumstine S et al. Gender disparities in depression severity and coping among people living with HIV/AIDS in Kolkata, India. PLoS ONE. 2018;13(11):e0207055.

Antwal M, Gurjar R, Chidrawar S, Pawar J, Gaikwad S, Panchal N et al. Clinical profile of HIV infected patients attending a HIV referral clinic in Pune, India. Indian J Med Res. 2014;140(2):271-7.

Kadam D, Chandanwale A, Bharadwaj R, Nevrekar N, Joshi S, Patil S et al. High Prevalence of Cryptococcal Antigenaemia amongst Asymptomatic Advanced HIV Patients in Pune, India. Indian J Med Microbiol. 2017;35(1):105-8.

Chakraborty A, Hershow RC, Qato DM. Adherence to Antiretroviral Therapy Among HIV Patients in India: A Systematic Review and Meta-analysis. AIDS Behav. 2020;24(2):2130-48.

Sabri B, McFall AM, Solomon SS, Srikrishnan AK, Vasudevan CK, Anand S et al. Gender Differences in Factors Related to HIV Risk Behaviors among People Who Inject Drugs in North-East India. PLoS ONE. 2017;12(1):e0169482.

Gupta N, Niyas VKM, Nischal N, Soneja M, Vinod KS, Ranjan S et al. Epidemiological trends in patients living with human immunodeficiency virus: a 13-year experience from a tertiary care center in India. Infez Med. 2019;27(3):308-15.

Kilaru KR, Punuru L, Garimella VR, Kande D. CD4 count at the time of presentation in newly diagnosed HIV patients in a tertiary care hospital in south India: implications for the programme. Int J Res Med Sci. 2019;7(2):512-8.

De La Mata, Nicole L, Ly, Penh S, Nguyen, Kinh VM et al. Loss to Follow-up Trends in HIV-Positive Patients Receiving Antiretroviral Treatment in Asia from 2003 to 2013. J Acquired Immune Deficiency Syndromes. 2017;74(5):555-62.

Kamath R, Sharma V, Pattanshetty S, Hegde MB, Chandrasekaran V. HIV-TB coinfection: Clinico-epidemiological determinants at an antiretroviral therapy center in Southern India. Lung India. 2013;30(4):302-6

Iredia CH, Oguntibeju OO, Lewis HA, Mokwena K. Trends and characteristics of patients admitted with musculoskeletal tuberculosis to a referral hospital from 2003 to 2008. Afr J Microbiol Res. 2011;5:532-40.

Vajpayee M, Kanswal S, Seth P, Wig N, Pandey RM. Tuberculosis infections in HIV-infected Indian Patients. AIDS Patient Care STDS. 2004;18:209-13.

National AIDS Control Organization (NACO). Technical Report: 2017. Available at: Accessed on 24 January 2021.