Epidemiological snapshot of carcinoma lung at a tertiary cancer centre of Bihar, India

Authors

  • Amrita Rakesh Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India
  • Pritanjali Singh Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India
  • Manika Verma Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India
  • Avik Mandal Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India
  • Dharmendra Singh Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India
  • Rakesh Ranjan Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20214581

Keywords:

Lung cancer, Epidemiology, Tuberculosis, Anaplastic lymphoma kinase

Abstract

Background: According to the GLOBOCAN 2020 report, the estimated incidence of lung cancer in India was 72,510 in all ages and both sexes. In incidence, lung cancer ranked fourth overall among the various types of cancer. To study epidemiological profile in terms of clinical presentation, stage, risk factors and factors associated with late stage presentations at a newly established tertiary cancer care hospital Bihar

Methods: This was a retrospective-prospective analysis of collected data of histopathologically proven lung cancer cases in the Outpatients department (OPD) of Department of Radiotherapy, All India Institute of Medical Sciences (AIIMS), Patna over a period of 2.5 years from March 2018 to October 2020.

Results: There were 140 patients, with a median age of 56 years, 59.28% (n=83) were smokers, 37.14% (n=52) used chewing tobacco, 24.28% (n=34) worked on earthen stoves and 15% (n=21) had passive smoking exposure. The male-to-female ratio was 1.64:1. Non-small cell lung carcinoma comprised 87.85% (n=123), stage IV presentation in 76.42% (n=107) cases with the most common site of metastases being bone (35.51%, 38 patients). IHC was performed on 64 patients (45.71%) of total 140 patients of which 51 patients were of adenocarcinoma histology. 35.29% (n=18) were EGFR positive and 28.57% (n=4) tested ALK positive. 4 patients tested for ROS-1 were negative. 32.14% (n=45) cases were treated empirically for Tuberculosis on the finding of chest X-ray only.

Conclusions: Majority of the patients were males in advanced stage. Bone is the most common site of metastases. Long empirical treatments lead to late presentations.

Author Biography

Amrita Rakesh, Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India

Department of Radiation Oncology, All India Institute of Medical sciences, Patna, Bihar, India

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https://www.indianjcancer.com/article.asp?issn=0019-509X;year=2017;volume=54;issue=1;spage=305;epage=307;aulast=Chatterjee

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Published

2021-11-24

How to Cite

Rakesh, A., Singh, P., Verma, M., Mandal, A., Singh, D., & Ranjan, R. (2021). Epidemiological snapshot of carcinoma lung at a tertiary cancer centre of Bihar, India. International Journal Of Community Medicine And Public Health, 8(12), 5867–5873. https://doi.org/10.18203/2394-6040.ijcmph20214581

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Original Research Articles