Comparison of different induction agents used for rapid sequence intubation

Authors

  • Enass Farouk Aboshoushah Department of Anaesthesia, King Abdulaziz Hospital, Jeddah, Saudi Arabia
  • Aisha Yahya Saddeek Department of Intensive Care Unit, King Fahad Hospital, Medina, Saudi Arabia
  • Wail Mohammad Alanazi Department of Pharmacy, Prince Mutaib bin Abdulaziz Hospital, Sakaka, Saudi Arabia
  • Mohammed Abdulaziz Alghamdi College of Medicine, Ibn Sina National College, Jeddah, Saudi Arabia
  • Raneem Abdulhamid Alrahwan College of Medicine, Ibn Sina National College, Jeddah, Saudi Arabia
  • Nojoud Adnan Khayat Department of Pharmacy, Al Noor Specialist Hospital, Mecca, Saudi Arabia
  • Muqrin Safar Alotaibi College of Medicine, Shaqra Medical University, Aldawadmi, Saudi Arabia
  • Khaled Nasser Alharbi Department of Emergency Medicine, Imam Abdulrahman Al Faisal Hospital, Riyadh, Saudi Arabia
  • Ahmed Mohammed Kurdi Department of Emergency Medicine, King Salman Medical City, Medina, Saudi Arabia
  • Shouq Sulaiman Alrumayh College of Medicine, Qassim University, Qassim, Saudi Arabia
  • Rimaz Mohammed Alassiri College of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20213654

Keywords:

Induction agents, Rapid sequence intubation, Benzodiazepines, Propofol, Etomidate

Abstract

Securing the airway is the first step that clinicians take care of for clinically unstable patients. Rapid sequence intubation (RSI) has been reported by many clinicians to effectively achieve this. Many agents have been reported in the literature as effective induction agents for RSI. In this literature review, we have discussed the efficacies of the different induction agents that are commonly reported in the literature for RSI. Furthermore, RSI is done by paralytic and sedative agents that rapidly render the patient flaccid and unconscious to facilitate the emergent approaches to achieve successful tracheal intubation and minimize adverse events. We have discussed the efficacies and adverse events of benzodiazepines and barbiturates, ketamine, propofol, and etomidate. Each of these modalities has its advantages and adverse events, and clinicians should choose what is best for their patients based on the aforementioned discussion for each drug modality. We recommend that further investigations might be needed for further optimization of the induction agent and the relevant doses.

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Published

2021-09-27

How to Cite

Aboshoushah, E. F., Saddeek, A. Y., Alanazi, W. M., Alghamdi, M. A., Alrahwan, R. A., Khayat, N. A., Alotaibi, M. S., Alharbi, K. N., Kurdi, A. M., Alrumayh, S. S., & Alassiri, R. M. (2021). Comparison of different induction agents used for rapid sequence intubation. International Journal Of Community Medicine And Public Health, 8(10), 5069–5074. https://doi.org/10.18203/2394-6040.ijcmph20213654

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Section

Review Articles