The prevalence and risk factors for Mallory-Weiss syndrome: a systematic review and meta-analysis

Authors

  • Abdulmajeed Albalawi Faculty of Medicine, Tabuk University, Tabuk, Saudi Arabia
  • Hasan Alabbadi Department of Emergency Medicine, Dhurma General Hospital, Dhurma, Riyadh, Saudi Arabia
  • Tamim Almoqbell Department of Emergency Medicine, Dhurma General Hospital, Dhurma, Riyadh, Saudi Arabia
  • Omar Alsayari Department of Surgery, King Abdulaziz Hospital, Jeddah, Saudi Arabia
  • Abdulrahman Aljohani College of Medicine, Taibah University, Madinah, Saudi Arabia
  • Ohoud Almana The program of Medicine, Ibn Sina National College, Jeddah, Saudi Arabia
  • Amal Alenazi Faculty of Medicine, Tabuk University, Tabuk, Saudi Arabia
  • Nawal Alanazi Faculty of Medicine, Tabuk University, Tabuk, Saudi Arabia
  • Maha Al-thuwaybi College of Medicine, Taif University, Taif, Saudi Arabia
  • Anas Aljohani College of Medicine, Taibah University, Madinah, Saudi Arabia
  • Mohammed Alshuhayeb College of Medicine, Shaqra University, Shaqra, Saudi Arabia
  • Haya Binhashr The program of Medicine, Ibn Sina National College, Jeddah, Saudi Arabia
  • Maram Almutairi College of Medicine, Jordan university of science and Technology, Irbid, Jordan
  • Essam Alameer Faculty of Pharmacy, Jazan University, Jazan, Saudi Arabia
  • Fahad Alsuhaymi Faculty of Medicine, Tabuk University, Tabuk, Saudi Arabia
  • Dina Abusabir Faculty of Medicine, Tabuk University, Tabuk, Saudi Arabia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20211937

Keywords:

Mallory Weiss syndrome, Prevalence, Risk factors, Hiatus hernia, Alcohol

Abstract

Mallory-Weiss syndrome (MWS), characterized by tearing and blood from mouth and stool, is a complication of gastro esophageal tract. The prevalence varies and there are a number of risk factors associated with MWS development. The present study is a systematic review and meta-analysis to determine the prevalence and various risk factors associated with Mallory-Weiss syndrome development. We systematically searched literature using specified keywords, reviewed it, and selected articles based on the inclusion and exclusion criteria. Qualitative data was presented in tables and the quantitative data was used to draw forest plots. Percentage was used to determine overall effect size for prevalence and OR and 95% CIs was used to determine overall effect size of risk factors. Our analysis of 21 studies showed that the overall effect size for prevalence was 15.46% with 95% CI of 13.63-17.29. The pooled effect size for hiatus hernia as risk factor was found to be OR 1.96 with 95% CI of 1.96 (1.73-2.22). The pooled effect size for alcohol as risk factor OR 0.81 with 95% CI of 1.96 (0.63-1.05). Finally, we found the pooled effect size for hiccups as risk factor OR 1.04 with 95% CI of 1.96 (0.78-1.39). Mallory-Weiss syndrome is not widely prevalent in various populations. There are a number of risk factors for MWS and hiatus hernia is most significant. Alcohol consumption is not strong predictor and hiccups are an emerging risk factor. There is a need for new studies with large number of subjects and controlled conditions.

 

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Published

2021-05-25

How to Cite

Albalawi, A., Alabbadi, H., Almoqbell, T., Alsayari, O., Aljohani, A., Almana, O., Alenazi, A., Alanazi, N., Al-thuwaybi, M., Aljohani, A., Alshuhayeb, M., Binhashr, H., Almutairi, M., Alameer, E., Alsuhaymi, F., & Abusabir, D. (2021). The prevalence and risk factors for Mallory-Weiss syndrome: a systematic review and meta-analysis. International Journal Of Community Medicine And Public Health, 8(6), 3096–3106. https://doi.org/10.18203/2394-6040.ijcmph20211937

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Section

Meta-Analysis