Evaluation of immune response to hepatitis B vaccine among health care workers at a tertiary care hospital in south India: a retrospective record based study

Archana Siddaiah, Kona Chandralekha, Apoorva Dore, Naveen Ramesh, Bobby Joseph


Seroprevalence of hepatitis B virus (HBV) among healthcare workers (HCWs) is two to four times higher than that of the general population due to repeated exposure. To determine the hepatitis B (hep B) vaccination status, non-response rate to (hep B) and its determinants among HCWs at a tertiary care teaching hospital in south India. A secondary analysis of the medical records of a group of HCWs who joined the hospital from 1st January 2015 to 31st December 2016 was done. A total of 451 HCWs received the vaccine at the study hospital. Mean age of the HCWs was 25.3±6.1 years, majority 374 (82.1%) of them were females and joined as staff nurses 213 (47.2%). Only 164 (36.3%) had received all 3 doses of hep B vaccination. Complete vaccination with (hep B) among HCWs was poor. Health education and suitable administrative controls must be instituted to ensure protection.


Hepatitis B vaccine, Health care workers, Occupational health, Workplace safety

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