Diabetic dyslipidemia and type 2 diabetes mellitus as early as six weeks post-partum: a nested case control study

Authors

  • Meesha Iqbal Department of Community and Public Health, Idaho State University, Idaho, USA
  • Paramjit Gill Warwick Medical School-Health Sciences, University of Warwick, UK
  • Iqbal Azam Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan
  • Romaina Iqbal Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20212023

Keywords:

Dyslipidemia, Diabetes mellitus, Gestational diabetes mellitus

Abstract

Women who develop diabetes during pregnancy (Gestational diabetes mellitus-GDM) increase their risk of developing type 2 diabetes mellitus (T2DM) post-partum by 70%. The average time to develop T2DM varies and is not widely studied. T2DM is associated with increased risk of developing dyslipidemia leading to cardiovascular diseases. We intended to study the association of dyslipidemia and T2DM as early as 6 weeks post-partum. A matched case control study was designed, and conditional logistic regression analysis applied to get adjusted matched odds with 95% confidence intervals. Our study revealed increased serum LDL levels in the cases compared to the controls (p=0.03). However, no association was seen with other lipid parameters.

 

References

World Health Organization, media centre, fact sheets, Diabetes. Available at: http://www.who.int/mediacentre/factsheets/fs312/en/. Accessed on 2018 Jan 01.

International diabetes federation. IDF Diabetes Atlas-8th Edition. Available at: http://www.diabetesatlas.org/resources/2017-atlas.html. Accessed on 2018 Jan 01.

National Institute for Health and Care Excellence (NICE). Diabetes in pregnancy : management of diabetes and its complications from pre-conception to the post-natal period. Available at: https://www.nice.org.uk/guidance/ng3. Accessed on 2017 Jan 01.

Every 4th Pakistani suffering from diabetes. The Nation. 2017. Available at: https://nation.com.pk/19-Aug-2017/every-4th-pakistani-suffering-from-diabetes. Accessed on 2018 Jan 01.

CIME, "CIME Newsletter: November 2017", 2017. CIME Newsletter. Book 7. https://ecommons.aku.edu/cime_newsletter/7. Accessed on 2020 Jan 01.

Skolnik NS, Russell JJ, American Diabetes Association. Diabetes professional resources online; 2017 July 26 [updated 2017 Aug; cited 2017 Jan 01]. Available at: https://professional.diabetes.org/podcast/diabetes-core-update-august-2017. Accessed on 2020 Jan 01.

The top 10 causes of death: World health organization. Updated 2017 Jan; cited 2018 Jan 26. Avialable at: http://www.who.int/mediacentre/factsheets/fs310/en/. Accessed on 2018 Jan 01.

Dixit AK, Dey R, Suresh A, Chaudhuri S, Panda AK, Mitra A, Hazra J. The prevalence of dyslipidemia in patients with diabetes mellitus of ayurveda Hospital. J Diabetes Metab Disord. 2014 May 22;13(1):58.

Meenu J, Jadeja Jayendrasinh M, Neeta M. Correlation between HbA1c values and lipid profile in type 2 diabetes mellitus. IJBAP. 2013;147:35-40.

Zhu XW, Deng FY, Lei SF. Meta-analysis of Atherogenic Index of Plasma and other lipid parameters in relation to risk of type 2 diabetes mellitus. Prim Care Diabetes. 2015;9(1):60-7.

Vergès B. Pathophysiology of diabetic dyslipidaemia: where are we?. Diabetologia. 2015;58(5):886-99.

Downloads

Published

2021-05-25

How to Cite

Iqbal, M., Gill, P., Azam, I., & Iqbal, R. (2021). Diabetic dyslipidemia and type 2 diabetes mellitus as early as six weeks post-partum: a nested case control study. International Journal Of Community Medicine And Public Health, 8(6), 3116–3119. https://doi.org/10.18203/2394-6040.ijcmph20212023

Issue

Section

Short Communication