A cross-sectional study to assess impact of COVID-19 infection amongst patients with chronic kidney disease

Authors

  • Harshalkumar N. Mahajan Department of Community Medicine, L.T.M. Medical College and General Hospital, Sion, Mumbai, Maharashtra, India
  • Smita S. Chavhan Department of Community Medicine, Seven Hills, DCH, Marol, Andheri, Mumbai, Maharashtra, India
  • Chinmay Gokhale Department of Community Medicine, HBTMC and Dr. R. N. Cooper Hospital, Juhu, Mumbai, Maharashtra, India
  • Balkrishna B. Adsul Department of Community Medicine, Seven Hills, DCH, Marol, Andheri, Mumbai, Maharashtra, India
  • Maharudra Kumbhar Department of Community Medicine, Seven Hills, DCH, Marol, Andheri, Mumbai, Maharashtra, India
  • Aniket Ingale Department of Community Medicine, HBTMC and Dr. R. N. Cooper Hospital, Juhu, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20210845

Keywords:

COVID-19, CKD, Impact, Mortality rate, Recovery rate

Abstract

Background: In December 2019, a series of unknown origin cases of acute respiratory illness occurred in Wuhan, Hubei Province, China. Although diffuse alveolar damage and acute respiratory failure were the main features of COVID-19, the involvement of other organs needed to be explored. After lung infection, the virus may enter the blood, accumulate in the kidney, and cause damage to resident renal cells. Hence, this study was planned to analyze the potential impact of this pandemic of COVID-19 amongst the chronic kidney disease (CKD) patients.

Methods: Cross-sectional observational study was conducted at Seven Hills Dedicated Covid-19 hospital, Andheri, Mumbai. Data was collected from hospital records of CKD patients admitted in the study duration.

Results: This study was conducted on 310 patients. Mean age was 53.33+14.21 years, and 191 (61.6%) of patients were male while mean duration of hospitalization was 16.78+10.31. Majority of the patients presented with symptoms like fever 80%, breathlessness 61.3%, and co-morbidities like Diabetes Mellitus 65.5% followed by Hypertension 61.8%. Patients (15.5%) over age of 60 years tested swab report positive for more than 5 times. Recovery rate being 76.1% while mortality rate found to be 23.87%.

Conclusions: Early detection and effective intervention may help to reduce deaths among CKD patients with COVID-19.

References

Li Q, Guan X, Wu P. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020;382:1199-1207.

Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733.

Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395:556-74.

Huang C, Wang Y, Li X. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497-506.

Chu KH, Tsang WK, Tang CS. Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Kidney Int. 2005;67:698-705.

Guidelines for dialysis of Covid-19 patients. Ministry of Health & family Welfare, Government of India.

Cheng Y, Luo R, Wang K, Yao Y, Ge S. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney International, 2020;97(5):829-38.

Oyelade T, Alqahatani J, Canciani G. Prognosis of COVID-19 in Patients with Liver and Kidney Diseases: An Early Systematic Review and Meta-Analysis. Trop. Med. Infect. Dis. 2020;5:80.

India’s Covid cases world’s 2nd highest. Available at https://timesofindia.indiatimes.com/india/indias-covid-cases-worlds-2nd-highest/articleshow/77956328.cms

Goicoechea M, Ca´mara LAS. COVID-19: clinical course and outcomes of 36 haemodialysis patients in Spain. Kidney International. 2020;98:27-34.

Jeremy AW, Karen K. Wong, Christine M. Szablewski, Characteristics and Clinical Outcomes of Adult Patients Hospitalized with COVID-19 Georgia, March 2020. US Department of Health and Human Services/Centers for Disease Control and Prevention MMWR. 2020;69(18).

Yamada T, Mikami T, Chopra N. Patients with chronic kidney disease have a poorer prognosis of coronavirus disease 2019 (COVID 19): an experience in New York City. International Urol Nephrol. 2 May 2020. 2020.

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Published

2021-02-24

How to Cite

Mahajan, H. N., Chavhan, S. S., Gokhale, C., Adsul, B. B., Kumbhar, M., & Ingale, A. (2021). A cross-sectional study to assess impact of COVID-19 infection amongst patients with chronic kidney disease. International Journal Of Community Medicine And Public Health, 8(3), 1466–1470. https://doi.org/10.18203/2394-6040.ijcmph20210845

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Original Research Articles