DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20210843

A study on coverage and compliance of mass drug administration for lymphatic filariasis in Prayagraj District, Uttar Pradesh, India

Santraj Ram, Shiv Prakash, Richa Singh, Gyan Prakash, Deepak Anand

Abstract


Background: Lymphatic filariasis is one of the six infectious diseases identified by the International Task Force for Disease Eradication as “eradicable” or “potentially eradicable. It is estimated that, to interrupt transmission of lymphatic filariasis, MDA compliance must exceed 65–75%. This study was conducted to assess coverage and compliance of mass drug administration for lymphatic filariasis in Prayagraj District.

Methods: This was a pre-tested, questionnaire based cross-sectional study. The study subjects (508) were selected randomly from rural (clusters of three villages) and urban (cluster of one ward) area of Prayagraj, Uttar Pradesh. Data was analyzed by using software SPSS version 23.0 and Chi-square test was used to test the association between the different variables. p-value less than 0.05 was considered as significant.

Results: The overall coverage rate, compliance rate, coverage-compliance gap and effective coverage rate of study population (eligible for MDA) in Prayagraj District were 69.94%, 84.19%, 15.81% and 58.88% respectively. The coverage rate and effective coverage rate were 78.71% and 64.85% respectively among urban area as well as 66.99% and 56.88% respectively among rural area.

Conclusions: The coverage rate and effective coverage rate were higher among population in urban area as compared to rural area while compliance rate was lower and hence coverage-compliance gap was higher among population in urban area as compared to rural area. The most common reason for not consuming drugs was ‘drugs not delivered by drug distributors’ (73.11%).


Keywords


Coverage rate, Compliance rate, Effective coverage rate, Lymphatic filariasis, MDA

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References


Saeed M, Al-Shammari EM, Khan S, Alam MJ, Adnan M. Monitoring and evaluation of lymphatic filariasis interventions: cur-rent trends for diagnosis. Rev Med Microbiol. 2016;27(2):75-83.

Koroma JB, Bangura MM, Hodges MH, Bah MS, Zhang Y, Bockarie MJ. Lymphatic filariasis mapping by Immunochromatographic Test cards and baseline microfilaria survey prior to mass drug admi¬nistration in Sierra Leone. Parasit vectors. 2012;5(1).

Centers for Disease Control and Prevention. Recommendations of the International Task Force for Disease Eradication. Morbidity and Mortality Weekly Report. 1993;42(RR-16):1-27.

Ichimori K, King JD, Engels D. Global Programme to Eliminate Lymphatic Filariasis: the processes underlying programme success. PLoSNegl Trop Dis. 2014;8(12):e3328.

National Roadmap for Elimination of Lymphatic Filariasis under NVBDCP Directorate General of health Services, Ministry of health & family welfare, Government of India.

Government of India, Chapter 05 Annual Report 2018-19 under Disease Control Programmes, Ministry of health & family welfare.

Gyapong JO, Kumaraswami V, Biswas G, Ottesen EA. Treatment strategies underpinning the global programme to eliminate lymphatic filariasis. Expert opinion on pharmacotherapy. 2005;6(2):179-200.

National Vector Borne Disease Control Programme, Directorate General of Health Services, Ministry of Healthand Family Welfare, Government of India. Lymphatic Filariasis. Upscaling of mass drug administration. Available at: (http://nvbdcp.gov.in/filariasis-new.html).

Stolk WA, Swaminathan S, van Oortmarssen GJ, Das PK, Habbema JDF. Prospects for elimination of bancroftianfilariasis by mass drug treatment in Pondicherry, India: a simulation study. J Infect Dis, 2003;(188):1371-81.

Patel PK. Mass drug administration coverage evaluation survey for lymphatic Filariasis in Bagalkot and Gulbarga districts. Indian J Community Med. 2012;37:101-6.

Lahariya C, Mishra A. Strengthening of mass drug administration implementation is required to eliminate lymphatic filariasis from India: An evaluation study. J Vector Borne Dis. 2008;45:313-20.

Singh SK, Agrawal M, Mohan U, Pandey P. Filarial elimination in India missing its deadline- Evidence from cross sectional study of four District of Uttar Pradesh. Int J Trop Dis Health. 2015;13(1):1-7.

Gowda P. Post mass drug administration evaluation survey for lymphatic filariasis in Bidar district of Karnataka. Int J Med Sci Public Health. 2013;2(2):235-8.

Sinha N, Malik S, Panja TK, Haldar A. Coverage and compliance of mass drug administration in Limphaticfilariasis: A comparative analysis in a District of West Bengal, India. Glob J Med Public Health. 2012;1(1).

Government of India. Accelerated Plan for Elimination of Lymphatic Filariasis under NVBDCP Directorate General of health Services, Ministry of health & family welfare.

Kulkarni P, Amoghashree, Krishnaveni YS, Murthy MRN, Kumar KR. Coverage and compliance towards mass drug administration programme against lymphatic filariasis in Vijayapura (Bijapur) district, Karnataka, India. Int J Community Med Public Health. 2018;5(10):4311-5.

Ganapa P, Jothula KY, Guthi VR, Abhishek P, Jyothi V, Sreeharshika D, et al. Evaluation of coverage of mass drug administration programme conducted in Nalgonda district of Telangana state. Int J Community Med Public Health. 2018;5(12):5178-83.

Kulkarni P, Thomas JJ, Dowerah J, Murthy MRN, Ravikumar K. Mass drug administration programme against lymphatic filariasis-an evaluation of coverage and compliance in a northern Karnataka district, India. Clinical Epidemiology and Global Health. 2020;8:87-90.

Bhatia V, Giri PP, Sahoo SS, Preeti PS, Sahu DP. Mass drug administration (MDA) for elimination of Lymphatic Filariasis: Experiences from Nayagarh District of Odisha, India. I J Community Health, 2018;30(3):287-92.

Rajkumar PS, Pandve TK, Nagaiah G, Tajmul S, Arun B, Inamdar NS. An Operational Research on Annual Mass Drug Administration (MDA) For Elimination of Lymphatic Filariasis in Medak District, Telangana. IAIM. 2016;3(7):239-44.

Babu BV, Babu GR. A systematic review on coverage of, and compliance with, mass drug administration under the programme to eliminate lymphatic filariasis in India.R Soc Trop Med Hyg. 2014.