Clinical and epidemiological spectrum of coronavirus disease 2019 in Central Kerala: a retrospective case series

Authors

  • Ronnie Thomas Department of Community Medicine, Government Medical College, Kottayam, Kerala, India http://orcid.org/0000-0002-6073-7181
  • Bins M. John Department of General Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India
  • Joe Thomas Koothapally Department of General Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India
  • Sanjeev Kumar Department of Paediatrics Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India
  • Supriya Adiody Department of Pulmonology, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India
  • Venu Balachandran Department of General Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India
  • Chithra Valsan Department of Microbiology, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India
  • Praveenlal Kuttichira Principal, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20210852

Keywords:

COVID-19, Kerala, Clinical spectrum, Epidemiological profile, Case series

Abstract

Kerala state in India was known for its early response to the Covid-19 pandemic by public health mitigation measures through science-based advocacy. The objective of this study was to analyze epidemiological and clinical characteristics of COVID-19 patients admitted to a tertiary care center in central Kerala. This retrospective case series was undertaken by reviewing the medical records and extracting the epidemiological data, clinical symptoms and laboratory findings of consecutive patients admitted between April 1st and September 31, 2020. Clinical and demographic parameters of hospitalized patients were analyzed regarding their association with the severity of disease. The mean age of the patients was 35.8 years with significant male predominance. Shopkeepers represented 15.6% of the patients and healthcare workers represented 12.5%. Primary contact with a known case was documented in 62.5% of the patients. Asymptomatic patients constituted 25% of the patients and the most commonly experienced symptoms were fever, cough, breathlessness and diarrhea. Three patients had atypical presentations in the form of generalized seizures, intussusception and generalized anxiety with suicidal ideation. Neutrophilia and Lymphopenia were the most dominant laboratory finding. The clinical spectrum of COVID-19 in the study population is wider than previously described in literature.

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Author Biographies

Ronnie Thomas, Department of Community Medicine, Government Medical College, Kottayam, Kerala, India

Assistant Professor of Community Medicine

Bins M. John, Department of General Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Professor Of Medicine

Joe Thomas Koothapally, Department of General Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Associate Professor of Medicine

Sanjeev Kumar, Department of Paediatrics Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Professor of Pediatrics

Supriya Adiody, Department of Pulmonology, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Professor of Pulmonology

Venu Balachandran, Department of General Medicine, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Assistant Professor of Medicine

Chithra Valsan, Department of Microbiology, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Professor of Microbiology

Praveenlal Kuttichira, Principal, Jubilee Mission Hospital, Medical College and Research Institute, Thrissur, Kerala, India

Principal and Professor of Psychiatry

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Published

2021-02-24

How to Cite

Thomas, R., John, B. M., Koothapally, J. T., Kumar, S., Adiody, S., Balachandran, V., Valsan, C., & Kuttichira, P. (2021). Clinical and epidemiological spectrum of coronavirus disease 2019 in Central Kerala: a retrospective case series. International Journal Of Community Medicine And Public Health, 8(3), 1503–1507. https://doi.org/10.18203/2394-6040.ijcmph20210852

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Section

Case Series