Reduction of Staphylococcus aureus bacteria collaboration in diabetic ulcers by giving virgin coconut oil

Siti Aisyah Nur, Siska Sakti Anggraini, Putri Dafriani, Honesty Diana Morika


Background: Diabetic ulcers often result in amputations. The bacteria found in diabetic ulcers are Enterobacter sp, Staphylococcus aureus, Salmonella sp and Pseudomonas sp. Nursing management of ulcer patients has been attempted but nothing has been effective yet. Using virgin coconut oil (VCO) contains anti-inflammatory, antipyretic and has an analgesic effect to increase the formation of new blood vessels with faster wound healing. Aim was to study the effect of wound care by giving VCO on the colonization of Staphylococcus aureus bacteria in diabetic ulcers.

Methods: Quasi-experimental research with the two-group pre-test and post-test design approach involved 36 diabetic ulcer patients with consecutive sampling by doing wound care for 4 days. The duration of treatment was 30-40 minutes. Data was taken by swab on wound fluid before and after the intervention. Bivariate analysis carried out t-independent test of DM ulcers.

Results: The results showed the average number of colony staphylococcus in the intervention group before being given wound care with VCO 72.88, while after being treated with 38.88 wound VCO and the average results of the number of colony staphylococcus in the control group before being treated with NaCl 77.88, whereas after being treated with VCO 38.88 wound with NaCl 72.88 in the statistical test the p value is 0,000.

Conclusions: There was a significant influence between the number of colony Staphylococcus in the control group and the intervention group.


Diabetic ulcer, Virgin coconut oil, Wound care

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Arista EK, Putri A. Home care in ulcus diabeticum care in Semarang city. J Injec. 2016;2(1):34-41.

Alavi A, Sibbald RG, Mayer D, Goodman L, Botros M, Armstrong DG, et al. Diabetic foot ulcers: pathophysiology and prevention. J Am Academy Dermatol. 2014;70(1):1-13.

Anshori A, Widayati N. The Effect of wound care using honey on Staphylococcus Aureus. Ba Pustaka Kesehat. 2014;2(2):499-506.

Handayani LT. Meta-analysis study of diabetes foot care care with modern dressing. Indones J Heal Sci. 2016;6(2):149-59.

Hussain FH, Thu HE, Nazrun A, Kesharwani P, Khan S. Phytotherapeutic potential of natural herbal medicines for the treatment of mild-to-severe atopic dermatitis : a review of human clinical studies. Biomed Pharmacother. 2017;93(1):596-608.

Nitbani FO, Siswanta FD. Isolation and antibacterial activity test of lauric acid from crude coconut oil. Procedia Chem. 2016;18(1):132-40.

Ibrahim NI, Wong SK, Mohamed IN, Mohamed N, Chin KY. Wound healing properties of selected natural products. Int J Environ Res Public Health. 2018;15(1):1-23.

Nevin G, Rajamohan T. Effect of topical application of virgin coconut oil on skin components and antioxidant status during dermal wound healing in young rats. Ski Pharmacol Physiol. 2010:23(1):290-7.

Silalahi J, Tripermata Y, Putra TE. Antibacterial activity of hydrolyzed virgin coconut oil. Asian J Pharm Clin Res. 2014;7(2):90-4.

Vitse J, Bekara F, Byun S, Herlin C, Teot L. A double-blind, placebo-controlled randomized evaluation of the effect of low-level laser therapy on venous leg ulcers. Int J Low Extrem Wounds. 2017;6(1):29-5.

Rahmadi A, Abdiah I, Dewi M, Purnaningsih T. physicochemical characteristics and antibacterial virgin coconut oil results of fermentation of lactic acid bacteria. Physicochem Antibact. 2013;3(1):57-9.

Liau KM, Lee YY, Chen CK, Rasool AHG. An open-label pilot study to assess the efficacy and safety of virgin coconut oil in reducing visceral adiposity. ISRN Pharmacol. 2011;2(1):1-7.

Widianingrum DC, Noviandi CT, Salasia SIO. Antibacterial and immunomodulator activities of virgin coconut oil (VCO) against Staphylococcus aureus. Heliyon. 2019;5(10):20-1.

Soliman AM, Lin LS, Ghafar NA, Das S. Virgin coconut oil and diabetic wound healing: histopathological and biochemical analysis. Eur J Anat. 2018;22(2):135-44.

Silalahi J, Surbakti C. Burn wound healing activity of hydrolyzed virgin coconut oil. Int J Pharm Tech Res. 2015;8(1):67-73.

Dafriani P, Niken N, Ramadhani N, Marlinda R. Potensi Virgin Coconut Oil (VCO) Pada Minyak Herbal Sinergi (MHS) Terhadap Ulkus Diabetes. J Kesehatan Perintis. 2020;7(1):51-6.

Abdo JM, Sopko NA, Milner SM. The applied anatomy of human skin: a model for regeneration. Wound Med. 2020;28(1):35-9.