Garlic: an alternative in reducing blood glucose on diabetic patients

Putri Dafriani, Roza Marlinda, Eliza Arman, Meldafia Idaman


Background: Diabetes mellitus (DM), a metabolic disorder characterized by an increasing of blood sugar (hyperglycemia). Medication is one of the seven pillars of diabetes managementt. Garlic (Allium sativum), an alternative herb, also has an antidiabetic effect. The purpose of this study was to investigate the effect of garlic on the blood sugar level in type 2 diabetes mellitus.

Methods: This study was a quasi-experimental design with two group post-test design. The participants were DM patients who only take medication without any supplemental herbs. The respondents were divided into two group; intervention group, given antidiabetic drugs and consume garlic 3 pieces of garlic/day for 2 weeks and control group only got antidiabetic drugs. Data were collected by performing blood sugar measurement using glucose-check on all respondents using capillary blood in the fingertips. Second measurement were taken after monitoring the consumption of garlic together with drugs for two weeks. Hypothesis testing used independent T-Test test.

Results: The study result found that the average of blood sugar level after administering the treatment is 240 mg/dl in the intervention group, and 284 mg/dl in control group. It can be concluded that the administration of 3 pieces of garlic combining with antidiabetic drugs for 2 weeks has not been able to reduce blood sugar levels into normal limits.

Conclusions: This combination found to lowering the blood sugar levels in a significant amount compare to only drugs. The length of the therapy could consider as a significant predictor.


Blood glucose, Diabetes mellitus, Garlic

Full Text:



Brunner DS, Smeltzer LS, Suddarth SC. Brunner and Suddarth’s textbook of medical-surgical nursing. 14th edition. Lippincott Williams and Wilkins. 2010.

Sinata N, Arifin H. Antidiabetic of Caramunting (Rhodomyrtus tomentosa (Ait.) Hassk) leaf water fraction against blood glucose levels of diabetes mice. J Pharm Clin Sci. 2016;3(1):72-8.

Bruton L. Goodman and Gilman. The Pharacological Basis of Therapeutics. 10th ed. McGraw Hill Education. 2007.

Majewski M. Allium sativum: facts and myths regarding human health. Rocz Państw Zaki Hig. 2014;65(1):1-8.

Buendía HA, González AT, Reyes S, Arroyo OG, García A, Tapia R, et al. Immuno-modulatory effects of the neutraceutical garlic derivative allicin in the progression of diabetic nephropathy. Int J Mol Sci. 2018;19(10):3107.

Suleria HAR, Butt MS, Khalid N, Sultan S. Garlic (Allium sativum): diet based therapy of 21st century - a review. Asian Pacific J Trop Dis. 2015;5(4):271-8.

Bayan L, Koulivand PH, Gorji A. Garlic: a review of potential therapeutic effects. Avicenna J Phytomed. 2014;4(1):1-14.

Wang W, Zhang J, Lan X, Wang H. Effect of garlic supplement in the management of type 2 diabetes mellitus (T2DM): a meta-analysis of randomized controlled trials. Food Nutr Res. 2017;61(1)20-7.

Putri D. Relationship of obesity and age with the event of diabetes mellitus type II. J Med Saintika. 2017;8(2):17-24.

Nuryanti I, Bantas K. Prevalance and risk factors for diabetes mellitus in women adult in Indonesia. 2010.

Isnaini R, Ratnasari N. Risk factors influence the incidence of type two diabetes mellitus. J Nursing Midwifery. 2018;14(1):59-68.

Parati G, Ochoa G, Salvi JE, Lombardi P, Bilo C. Prognostic value of blood pressure variability and average blood pressure levels in patients with hypertension and diabetes. Diab Care. 2013;36:13-7.

Shoshi H, Akter MSJ. Effects of garlic (Allium sativum) on blood glucose level in type 2 diabetes mellitus patients treated with metformin. J Enam Med Coll. 2017;7(3):57-63.

Naderi R, Mohaddes G, Mohammadi M, Alihemmati A, Badalzadeh Z. On oxidative stress and histopathology of cardiac tissue in streptozotocin-induced diabetic rats. 2015;102(4):380-90.

Dafriani P. The relationship between diet and physical activity against the incidence of diabetes mellitus in internal medicine polyclinic. J Kepara. 2017;13(2)2:87-9.

Garber P, Klein A, Bruce E, Sankoh S. Metformin‐glibenclamide versus metformin plus rosiglitazone in patients with type 2 diabetes inadequately controlled on metformin monotherapy. Diab Obes Metab. 2006;8(2):156-63.