Changes in body composition parameters with duration in type II diabetics: an observational study

Leena Raje, Pallavi Mhaskar


Background: Diabetes mellitus being a metabolic disorder lot of alteration takes place in body composition parameters such increase in fat mass, decrease in muscle mass, increase visceral fat. With advancing age, the predominant feature develops which is more prevalent in diabetes. These changes in body composition should be monitored. The changes if monitored at an early age, can be well managed and proper interventions can be developed.  The study was conducted to observe the changes taking place in the body composition parameters in individuals with type II diabetes with varied duration of the disease.

Methods: This cross- sectional study was done in 228 type II diabetic subjects from the clinics of the Mumbai and Pune. The baseline data was collected from the all the subjects coming to the clinic through the general questionnaire, Anthropometric measurements and Body composition analysis was done by the BIA principle-based Analyser.  Then these subjects were distributed according to the duration of the disease and then analysed.  The data was analysed using SPSS version 22 and mean values p values were obtained.

Results: The results showed that there is statistically significant increase in fat mass, visceral fat and decrease in muscle mass.

Conclusions: There is change in body composition parameters like decrease in muscle mass, increase in fat and visceral fat along with the increase in the duration of the disease.


Body composition, Type II diabetes, Sarcopenia

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Mane A. Ageing in India: Some Social Challenges to Elderly Care. J Gerontol Geriatr Res. 2016;5:2.

Census report. Available at: http://www.

Hentati H, Salloum C, Caillet P, Lahat E, Disabato M, Levesque E, et al. Risk Factors for Mortality and Morbidity in Elderly Patients Presenting with Digestive Surgical Emergencies. World J Surg 2018;42(7):1988-96.

Martin I, Collantes C, Galindo A, Gomez F. Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength? World J Diabetes. 2014;5(4):444-70.

Available at

Available at:

Morley J, Malstrom T, Rodriguez L, Sinclair A. Frailty, sarcopenia and diabetes. J Am Med Dir Assoc 2014;15(12):853-9.

Solanki J, Makwana A, Mehta H, Gokhale P, Shah C. Body Composition in Type 2 Diabetes: Change in Quality and not Just Quantity that Matters. Int J Prev Med 2015;6:122.

Park S, Goodpaster B, Strotmeyer E, Kuller L, Broudeau R, Kammerer C, et al. Accelerated loss of skeletal muscle strength in older adults with type 2 diabetes: the health, aging, and body composition study. Health, Aging, and Body Composition Study. Diabetes Care. 2007;30(6):1507-12.

Umegaki H. Sarcopenia and diabetes: Hyperglycemia is a risk factor for age-associated muscle mass and functional reduction. Diabetes Investig. 2015;6(6):623-4.

Jentoft A, Baeyens J, Boirie Y, Cederholm T, Landi F, Martin F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412-23.

Olivarius FN, Siersma VD, Rasmussen KR, Heitmann BL, Waldorff FB (2015) Weight Changes following the Diagnosis of Type 2 Diabetes: The Impact of Recent and Past Weight History before Diagnosis. Results from the Danish Diabetes Care in General Practice (DCGP) Study. PLoS ONE. 10(4):0122219.

Tyrovolas S, Kovanagi A, Olaya B, Luis J, Mirat M, Chatterji S, et al. Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi‐continent study. J Cachexia Sarcopenia Muscle. 2016;7(3):312-21.

Koo B, Roh E, Yang Y, Moon M. Difference between old and young adults in contribution of β-cell function and sarcopenia in developing diabetes mellitus. Diabetes Investig. 2016; .7(2):233-40.

Soniya I, Devi S, Rosemary S. Body Composition in Diabetes Mellitus. IOSR. 2014:13(1):68-70.

Scott D, Courten B, Ebeling P. Sarcopenia: a potential cause and consequence of type 2 diabetes in Australia's ageing population Med J Aust. 2016;3;205(7):329-33.

Trierweiler H, Kisielewicz G, Jonasson T, Petterle R, Moreira C, Zeghbi V, et al. Sarcopenia: a chronic complication of type 2 diabetes mellitus Diabetol Metab Syndr. 2018;10:25.

Fredman L, Cauley J, Satterfield S. The Health, Aging, and Body Composition (Health ABC) Study. Arch Intern Med. 2008;168(19):2154-62.

Feng L, Nyunt M, Feng M, Niti M, Tan B, Chan G, et al. Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial. J Med. 2015;128(11):1225-36.

Pegah N, Inglis J, Reilly W, Kelly O, Zllich J. Aging Human Body: changes in bone, muscle and body fat with consequent changes in nutrient intake. J Endocrinology. 2017;234:37-51.

Jang A. Sarcopenia, Frailty, and Diabetes in Older Adults. Diabetes Metab J. 2016;40(3):182-9.

Coin A, Sergi G, Inelmen E, Enzi G. Pathophysiology of Body Composition Changes in Elderly People. 2006; In: Mantovani G. et al. (eds) Cachexia and Wasting: A Modern Approach. Springer, Milano, 369-75.

Hamasakhi H, Kawashima Y, Sako A, Goto A, Yanai H. Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with Type II Diabetes. Sci Rep. 2017;7(1):7041.

Anbalagan V, Venkatraman V, Deepa M, Anjana R, Mohan V. The prevalence of presarcopenia in Asian Indian individuals with and without type 2 diabetes. Diabetes Technol Ther. 2013;15(9):768-75.