Seroconversion following H1N1 influenza vaccination among health care personnel in South Kerala, India

Anuja U.; Rajasi R. S.; Ratheesh K. H.; VijayaKumar K.; Amar Fettil

doi:10.18203/2394-6040.ijcmph20170267

Authors

Anuja U. Department of Community Medicine, Government Medical College, Thiruvananthapuram, Kerala, India
Rajasi R. S. Department of Community Medicine, Government Medical College, Manjeri, Kerala, India
Ratheesh K. H. Department of Community Medicine, Government Medical College, Thiruvananthapuram, Kerala, India
VijayaKumar K. Department of Community Medicine, Karakkonam Medical College, Thiruvananthapuram, Kerala, India
Amar Fettil Additional Director of Health Service, H1N1 Cell, DHS Office, Thiruvananthapuram, Kerala, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20170267

Keywords:

Health care workers, H1N1 vaccine, Swine influenza, Seroconversion, Vaccination

Abstract

Background: Health care workers were prioritized by World Health Organization (WHO) for H1N1 vaccination during 2009 swine influenza pandemic following which in Kerala, a total of 72,000 people mostly health care personnel were immunized with a single dose of inactivated split influenza monovalent H1N1 vaccine in 2010. The present study was carried out with the objective to find out the proportion of health care workers seroconverted in Kerala following H1N1 vaccination.

Methods:A cross-sectional study conducted in three districts of Kerala. Blood samples collected from 193 health staffs were analysed for H1N1 antibody titre 6 months following single dose of vaccination. Univariate analysis was done using proportions for qualitative variables.

Results: 99.5% of health staffs seroconverted following vaccination and none of them developed disease even after getting exposed to H1N1 cases thereafter.

Conclusions:Single dose of H1N1 vaccine is found to offer sufficient protection and should be recommended for health care workers. So all health care personnel shall consider H1N1 vaccination for their own protection.

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