An outbreak of diarrhoeal disease of El Tor Vibrio cholerae O1 Ogawa in and around Yavatmal district, Maharashtra, India in 2018

Swati S. Kale, Pragati A. Bulle, Durgesh G. Deshmukh, Supriya S. Tankhiwale, Vivek M. Gujar


Background: Epidemics of cholera have been reported from various parts of India. We investigated the epidemic of cholera that occurred in and around Yavatmal district in Maharashtra, India 2018, reported during March to July.

Methods: 711 stool samples collected from diarrhea patients were bacteriologically analyzed for their identification and antibiogram of Vibrio cholera.

Results: The cholera outbreak was caused by V. cholerae O1 Ogawa biotype El Tor. All the V. cholerae isolates from the stool samples were sensitive to tetracycline, doxycycline, ofloxacin, ciprofloxacin gentamycin, cotrimoxazole and resistant to ampicillin and ceftazidime.

Conclusions: The present outbreak was due to V. cholerae O1 Ogawa El Tor which seems to have completely replaced O139 serogroup of the previous outbreaks during the last decade.


V. cholerae, Outbreak, Yavatmal

Full Text:



WHO Scientific Working Group. Cholera and other vibrio associated diarrhoeas. Bull World Health Organ. 1980;58:353-74.

Peerapur BV, Srikant B, Sajjan AG, Patil SK, Mangalgi SS, Mantur BG, et al. An outbreak of cholera in Bijapur. Indian J Med Microbiol. 1996;14:221-2.

Saini S, Arora DR, Sikka R, Kundra N. Bacteriological study of cholera in Rohtak for five years. Indian J Med Microbiol. 1995;13:187-8.

Jesudason MV, John TJ. The appearance and spread of Vibrio cholerae O139 in India. Indian J Med Res. 1994;99:97-100.

Jalgaonkar SV, Fule RP. Cholera outbreak due to Vibrio cholerae O139 in Yavatmal (Maharashtra) in March-July 1993. Indian J Med Res. 1994;99:101-2.

Lahiri KK, Ayyagari A. Vibrio cholerae O139 in Lucknow. Indian J Med Microbiol. 1998;16(3):133.

Ameeta J, Turbadkar D, Deshmukh A, Dalal PJ. Emergence of Vibrio cholerae O139 in Mumbai (Maharashtra, India). Indian J Med Microbiol. 1999;17(4):198.

Fule RP, Jalgaonkar SV, Ingole KV, Fule C. Outbreak due to Vibrio cholerae El Tor & serotype O139 in Yavatmal (Maharashtra) during June-July, 1994. Indian J Med Res. 1995;101:62-3.

Agarwal V, Biswas M, Chande CA, Pathak AA, Saoji AM. Changing bacteriological profile of cholera in Nagpur, 1991-93. Indian J Med Res. 1994;100:93-4.

Raut S, Jalgaonkar SV, Tankhiwale NS, Agarwal VA. Reemergence of Vibrio cholerae O139 serogroup during 1998 in Nagpur (Maharashtra), India. Indian J Med Res. 1999;109:1-2.

Mishra M, Mohammed F, Akulwar SL, Katkar VJ, Tankhiwale NS, Powar RM. Re-emergence of El Tor vibrio in outbreak of cholera in & around Nagpur. Indian J Med Res. 2004;120:478-80.

Porter IA, Duguid JP. Vibrio: Aeromonas: Pleisomonas: Spirillum: Campylobacter. In: Collee JG, Duguid JP, Fraser AG, Marmion BP, editors. Mackie & McCartney’s practical medical microbiology, 13th ed. London: Churchill Livingstone; 1989: 505-524.

Bauer AW, Kirby WM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disc method. Am J Clin Pathol. 1966;45:493-6.

Pal BB, Khuntia HK, Samal SK, Kar SK, Patnaik B.Epidemics of severe cholera caused by El Tor Vibrio cholerae O1 Ogawa possessing the ctxB gene of the classical biotype in Orissa, India. Int J Infect Dis. 2010;14:384-9.

Roychoudhury A, Pan A, Dutta A, Mukhopadhyay A, et al. Emergence of Tetracycline resistant V. cholerae O1 serotype Inaba in Kolkata, India. Jpn J Infect Dis. 2008;61:128-9.

Ingole KV, Jalgaonkar SV, Fule C, Fule RP. Changing pattern of Vibrio cholerae serotype EL TOR and 0139 in Yavatmal (Maharashtra, India) during 1992 to 1994. Indian J Pathol Microbiol. 1997;40(3):369-71.

Kumar D, Taneja N, Gill H, Kumar R. Vibrio Cholerae O1 Ogawa Serotype outbreak in a village of Ambala district in Haryana, India. Indian J Community Med. 2011;36(1):66-8.