Cold agglutinin disease related mismatch between hematocrit and hemoglobin values

Authors

  • Emre Hoca Internal Medicine Clinic, Üsküdar State Hospital, İstanbul
  • Fatma Pınar Ziyadanoğlu Internal Medicine Clinic, Haseki Training and Research Hospital, İstanbul
  • Atay Can Kula Internal Medicine Clinic, Haseki Training and Research Hospital, İstanbul
  • Hayriye Esra Ataoğlu Internal Medicine Clinic, Haseki Training and Research Hospital, İstanbul

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20200465

Keywords:

Cold agglutinin disease, Hemoglobin-hematocrite mismatch, Epstein-Barr virus

Abstract

Autoimmune hemolytic anemia is a disease characterized by destruction of red blood cells (RBC) and anemia, caused by production of antibodies released against the body’s own RBCs. While this condition is more commonly idiopathic, it may accompany autoimmune diseases as well. Cold agglutinin disease (CAD) is a rare subtype of acquired autoimmune hemoliytic anemia, however, is an idiosyncratic clinical and pathological terminology, usually seen in older ages. This condition is caused by IgM antibodies called “cold agglutinins” formed against I antigens on RBC membranes which cause agglutination of RBCs at lower temperatures. In this case, a 56 year old male patient who was diagnosed with CAD secondary to Epstein-Barr virus (EBV) infection is being presented.

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Published

2020-01-28

How to Cite

Hoca, E., Ziyadanoğlu, F. P., Kula, A. C., & Ataoğlu, H. E. (2020). Cold agglutinin disease related mismatch between hematocrit and hemoglobin values. International Journal Of Community Medicine And Public Health, 7(2), 770–772. https://doi.org/10.18203/2394-6040.ijcmph20200465

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Section

Case Reports