Comparative study of pap smear and colposcopy guided biopsy in a district medical college
Keywords:Cervix, Screening, Pap smear, Colposcope, Biopsy
Background: Cancer cervix is the second most gynaecological and in India, one in fifty women suffer with cancer cervix and hence intense screening is mandatory.
Methods: This prospective study was conducted in SVS Medical College, a district tertiary centre. 100 women who presented to gynaecology outpatient department who fulfilled all the inclusion criteria were subjected to pap smear and colposcopic guided biopsy. The data was correlated and compared to critically evaluate the sensitivity and specificity of colposcopy versus Pap smear in the early detection of dysplasia.
Results: Colposcopy has far better sensitivity than Pap smear and almost negligible difference in specificity.
Conclusions: Colposcopy is definitely more sensitive and accurate than pap smear and can be included as the primary screening in district hospitals as a primary screening tool in detecting cancer cervix.
Basu PS, Sankaranarayanan R, Mandal R, Roy C, Das P, Visual Inspection of Cervix with acetic add and cytology in the early detection of cervical neoplasia in Kolkotta - India. Int J Cancer. 2005;13(6):626-32.
Kushtagi P, Fernandez P, Significance of Persistent Inflammatory, Cervical smears in Sexually active women of reproductive age. J Obstret Gynaecol India. 2002;52(1):124-6.
Londhe M, George SS, Seshadri I. Detection of CIN by VIA. Indian J Cancer 1997;34(2):88-91.
Novak’s Gynaecology, 13th Edition ; Intraepithelial disease of early cervical neoplasia, vagina and vulva, 2002: 47-506
Pete I, Toth V, Bosze P. The Value of Colposcopy in Screening Cervical Carcinoma. European J Gynaecol Oncol. 1998;19(2):120-2.
Sankaranarayanan R, SellersJW. Colposcopy and Treatment of CIN, A Beginner’s Manual. IARC Working Group.
Shalini R, Amita S, Neera MA. How alarming is post coital bleeding - a cytologic, colposcopic and histological evaluation. Gynaecol Obstet Invest. 1998;45(3):205 - 8.
Shakuntala Baliga. Principles and practices of colposcopy, I Edition, 2004, Jaypee publishers.
Sukhpreet SL, Dastur NA, Nanavatti MS. Comparison of colposcopy and pap smear : Sensitivity, specificity and predictive values. BHJ. 2000;42:4.
Vaidya A. Comparison of pap test among high risk and non risk female, Kathmandu university. Med J. 2003;1:8-13.