DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20192858

Depression in cancer patients undergoing chemotherapy in a tertiary care hospital: a cross-sectional study

Shivani S. Vaidya, Sarita K. Sharma

Abstract


Background: Cancer is the second most common cause of death after heart diseases and it accounted for 8.8 million deaths worldwide in 2015. The long course of treatment, repeated hospitalisations, and the side effects of chemotherapy along with the trauma of being diagnosed with cancer has a significant effect on psyche of cancer patient. Depression is the most frequent cancer related symptom and 15-25% of cancer patients are affected by depression. The aim of this study is to determine the levels of depression in cancer patients undergoing chemotherapy.

Methods: Present cross-sectional study was conducted amongst cancer patients undergoing chemotherapy at Day Care Centre, Department of Radiation Therapy and Oncology, Government Medical College and Hospital, Nagpur. 95 participants were interviewed using predesigned and pretested questionnaire based on the Beck’s Depression Inventory.

Results: Among the study subjects, 70 (73.69%) had depression of which 15 (21.42%) had borderline clinical depression, 44 (62.85%) had moderate depression and 11 (15.73%) had severe depression. None of the study subjects had extreme depression.

Conclusions: Majority of the study subjects receiving chemotherapy were depressed.


Keywords


Depression, Cancer patients, Chemotherapy, Tertiary care hospital

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References


"Cancer Fact Sheet N°297". World Health Organization. February 2018.

"Defining Cancer". National Cancer Institute.

American Cancer Society. Global Cancer Facts and Figures, 2018.

Sankaranarayanan R, Ramadas K, Qiao YL. Managing the changing burden of cancer in Asia. BMC Med. 2014;12:1-17.

Press Release: Report to the nation on the status of cancer in India. Based on Consolidated Cancer Registry Reports by Indian Council of Medical Research through its National Cancer Registry Programme. 2014.

Pandey M, Sarita GP, Devi N, Thomas BC, Hussain BM, Krishna R. Distress, anxiety, and depression in cancer patients undergoing chemotherapy. World J Surg Oncol. 2006;4:68.

Burgess C, Cornelius V, Love S, Graham J, Richards M, Ramirez A. Depression and anxiety in women with early breast cancer: Five year observational cohort study. BMJ. 2005;330:702-5.

Reich M, Lesur A, Pedrizet-Chevallier C. Depression, quality of life and breast cancer: A review of the literature. Breast Cancer Res Treat. 2008;110:9-17.

Shapiro SL, Lopez AM, Schwart GE, Bootzin R, Fiqueredo AJ, Braden CJ, et al. Quality of life and breast cancer relationships to psychosocial variables. J Clin Psychol. 2001;57:501-19.

Morris T, Greer HS, White P. Psychological and social adjustment to mastectomy. Cancer. 1997;40:2381-7.

Grassi L, Indelli M, Marzola M, Maestri A, Santini A, Piva E, et al. Depressive symptoms and quality of life in home-care-assisted cancer patients. J Pain Symptom Manage. 1996;12:300-7.

Spiegel D, Bloom JR. Pain in metastatic breast cancer. Cancer. 1983;52:341-5.

Colleoni M, Mandala M, Peruzzotti G, Robertson C, Bredart A, Goldhirsch A. Depression and degree of acceptance of adjuvant cytotoxic drugs. Lancet. 2000;356:1326-7

McLean LM, Jones JM. A review of distress and its management in couples facing end-of-life cancer. Psychooncology. 2007;16:603-16.

Adler NE, Page AEK (eds). Cancer Care for the Whole Patient: Meeting Psychosocial Health Needs, Institute of Medicine (US) Committee on Psychosocial Services to Cancer Patients/Families in a community Setting. Washington, DC, USA: Academics Press; 2008.

Mansoor S, Jehangir S. Anxiety, depression in patients receiving chemotherapy for solid tumors. Pak Armed Forces Med J. 2015;65(1):89-93.

http://www.med.navy.mil/NMCP2/PatientServices/SleepClinicLab/ Documents/Beck_Depression_Inventory.pdf.

Tavoli A, Mohagheghi MA, Montazeri A, Roshan R, Tavoli Z, Omidvari S, et al. Anxiety and depression in patients with gastrointestinal cancer: does knowledge of cancer diagnosis matter? BMC Gastroenterol. 2007;7:28.

Maguire GP, Julier DL, Hawton KE, Bancroft JH. Psychiatric morbidity and referral on two general medical wards. Br Med J. 1974;1(5902):268-270.

Moffic HS, Paykel ES. Depression in medical in-patients. Br J Psychiatry. 1975;126:346-53.

Massie MJ, Holland JC. Depression and the cancer patient. J Clin Psychiatr. 1990;50(suppl):12-7.

Katon WJ. Epidemiology and treatment of depression in patients with chronic medical illness. Dialogues Clin Neurosci. 2011;13:7-23.

Bhattacharyya S, Bhattacharjee S, Mandal T, Das DK. Depression in cancer patients undergoing chemotherapy in a tertiary care hospital of North Bengal, India. Indian J Public Health. 2017;61:14-18.

Nakaguchi T, Okuyama T, Uchida M, Ito Y, Komatsu H, Wada M, et al. Oncology nurses’ recognition of supportive care needs and symptoms of their patients undergoing chemotherapy. Jpn J Clin Oncol. 2013;43(4)369-76.

Jadoon NA, Shahzad MA, Munir W, Choudhary ZS. Assessment of depression and anxiety in adult cancer outpatients. BMC cancer. 2010;10(1):594.

Yusof S, Zakaria FN, Hashim NK, Dasiman R. Depressive symptoms among cancer patients undergoing chemotherapy. Procedia Soc Behav Sci. 2016;34:185-92.

Jang S, Ackler J, Braitman L, Tester W. Depression and quality of life in cancer undergoing chemotherapy: relation between Zung self-rating depression scale and functional assessment of cancer therapy-general. Commun Oncol. 2012;9:122-6.

de Souza BF, de Moraes JA, Inocenti A, dos Santos MA, de Camargo Silva AEB, Miasso AI. Women with breast cancer taking chemotherapy: depression symptoms and treatment adherence. Rev. Latino-Am. Enfermagem. 2014;22(5):1518-8345.

Polikandrioti M, Evaggelou E, Zerva S, Zerdila M, Koukoularis D, Kyritsi E. Evaluation of depression in patients undergoing chemotherapy. Health Sci J. 2008;2(3):162-72.