Unusual recurrent skin lesions: Bazin's disease

Muayad A. Merza, Dalshad K. Adham, Rafil T. Yaqo


A 46 year old Iraqi Kurd female patient was presented with recurrent round erythematous skin lesions on her upper and lower extremities mainly calves, lower abdomen, and buttock for 3 years. Routine laboratory investigations were unremarkable; however, based on strongly positive tuberculin skin test, positive interferon gamma release assay, histo-pathological findings and a response to anti-TB treatment, she was diagnosed with Erythem Induratum of Bazin (EIB). The patient was treated successfully with combination anti-TB drugs. The skin lesions disappeared after 2 months of the treatment. There was no recurrence of the lesions over a 6 month follow up period.


Erythema induratum of Bazin, Tuberculosis, IGRA, Iraqi Kurdistan

Full Text:



Cho KH, Lee DY, Kim CW. Erythema induratum of Bazin. Int J Dermatol. 1996;35(11):802-8.

Santos JB, Fiqueiredo AR. Cutaneous tuberculosis: epidemiologic, etiopathogenic and clinical aspects – part I. An Bras Dermatol 2014;89:219-28.

Merza MA, Farnia P, Salih AM, Masjedi MR, Velayati AA. First insight into the drug resistance pattern of Mycobacterium tuberculosis in Dohuk, Iraq: using spoligotyping and MIRU-VNTR to characterize multidrug resistant strains. J Infect Public Health 2011;4(1):41-7.

Vera-Kellet C, Peters L, Elwood K, Dutz JP. Usefulness of Interferon-g release assays in the diagnosis of erythema induratum. Arch Dermatol 2011;147(8):949– 52.

Frankel A, Penrose C, Emer J. Cutaneous tuberculosis: a practical case report and review for the dermatologist. J Clin Aesthet Dermatol 2009;2(10):19-27.

Campbell SM, Winkelmann RR, Sammons DL. Erythema Induratum Caused by Mycobacterium chelonei in an Immunocompetent Patient. J Clin Aesthet Dermatol. 2013;6(5):38-40.

Jacinto SS, Nograles KB. Erythema induratum of Bazin: role of polymerase chain reaction in diagnosis. Int J Derm. 2003;42(2):380-1.

Santa Cruz DJ, Strayer DS. The histologic spectrum of the cutaneous mycobacterioses. Human Pathol. 1982;13(5):485–95.

Bravo FG, Gotuzzo E. Cutaneous tuberculosis. Clin in Dermatol. 2007;25(2):173–80.

Gopinathan R, Pandit D, Joshi J, Jerajani H, Mathur M.. Clinical and morphological variants of cutaneous tuberculosis and its relation to Mycobacterium species. Indian J Med Microbiol. 2001;19(4):193-6.

Gilchrist H, Patterson JW. Erythema nodosum and erythema induratum (nodular vasculitis): diagnosis and management. Dermatol Ther. 2010;23(4):320-7.

Daher Ede F, Silva Júnior GB, Pinheiro HC, Oliveira TR, Vilar Mdo L, Alcântara KJ. Erythema induratum of Bazin and renal tuberculosis: report of an association. Rev Inst Med Trop Sao Paulo. 2004;46(5):295-8.