Risk factors for chronic kidney disease: a hospital based cross sectional study from Visakhapatnam

Sindhura Moparthi, Madhavi Seepana, Devi Madhavi Bhimarasetty


Background: Chronic kidney disease (CKD) is being increasingly recognised as a leading public health problem. In India, given its population >1 billion, the rising incidence of CKD is likely to pose major problems for both healthcare and the economy in future years. Diabetes and hypertension are strong predictors for development and progression of chronic kidney disease. The objective of the study was to assess risk factors for chronic kidney disease among patients undergoing dialysis in King George Hospital (KGH), Visakhapatnam.

Methods: This is an observational descriptive cross sectional study done in dialysis unit in KGH. A total of 100 patients were selected out of 141 registered CKD patients by simple random sampling technique. Study is done in the month of October- November 2015. A pretested semi structured schedule was administered. Informed written consent was taken from the patients. MS excel 2007 was used for data entry. Data was analysed by SPSS trial version 20. Categorical data was analysed by Chi square test.

Results: Among 100 study subjects 72 were females and 28 were males. 91% of the CKD patients were Hypertensive, among whom 73.6% were males and 26.4% were females. This difference was not found to be statistically significant (p=0.446). 22% of the CKD patients were Diabetic, among whom 81.8% were males and 18.2% were females.

Conclusions: Better understanding of the role of risk factors in CKD is needed. Large community based cross sectional studies are needed to study in detail about CKD risk factors.



Chronic kidney disease, Risk factors, Diabetes, Hypertension, Visakhapatnam

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National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39(2):1–266.

Mills KT, Xu Y, Zhang W. A systematic analysis of worldwide population-based data on the global burden of chronic kidney disease in 2010. Kidney Int. 2015;88:950–7.

Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:2038–47.

Kazancioğlu R. Risk factors for chronic kidney disease: an update. Kidney Int Suppl (2011). 2013;3(4):368–71.

Klag MJ, Whelton PK, Randall BL, Neaton JD, Brancati FL, Ford CE, et al. Blood pressure and end-stage renal disease in men. N Eng J Med. 1996;334:13–8

Brancati FL, Whelton PK, Randall BL, Neaton JD, Stamler J, Klag MJ. Risk of end-stage renal disease in diabetes mellitus: a prospective cohort study of men screened for MRFIT. Multiple Risk Factor Intervention Trial. JAMA. 1997;278:2069–74.

Tedla FM, Brar A, Browne R, Brown C. Hypertension in Chronic Kidney Disease: Navigating the Evidence International J Hypertension. 2011: ID 132405

McClellan WM, Flanders WD. Risk factors for progressive chronic kidney disease. J Am Soc Nephrol. 2003;14:65–70.

Song EY, McClellan WM, Mc Clellan A, Gadi R, Hadley AC, Krisher J, et al. Effect of community characteristics on familial clustering of end-stage renal disease. Am J Nephrol. 2009;30:499-504.

Mirrakhimov AE. Obstructive sleep apnea and kidney disease: is there any direct link. Sleep Breath. 2012;16:1009–16.

McClellan WM, Flanders WD. Risk factors for progressive chronic kidney disease. J Am Soc Nephrol. 2003;14:65–70.

Lea JP, Nicholas SB. Diabetes mellitus and hypertension: key risk factors for kidney disease. J Natl Med Assoc. 2002;94:7–15.

Huda MN, Alam KS, Harun UR. Prevalence of chronic kidney disease and its association with risk factors in disadvantageous population. Int J Nephrol. 2012;2012:267329.

WHO Obesity and Over weight: Fact sheet N’ 311(2016). Available at: factsheets/fs311/. Accessed on 28 February 2016.

Ghaderian SB, Beladi-Mousavi SS. The role of diabetes mellitus and hypertension in chronic kidney disease. 2014;3(4):109–10.

Singh AK, Farag YMK, Mittal BV, Subramanian KK, Reddy SRK, Acharya VN, et al. Epidemiology and risk factors of chronic kidney disease in India – results from the SEEK (Screening and Early Evaluation of Kidney Disease) study. BMC Nephrol. 2013;14:114.

Orantes CM, Herrera R, Almaguer M, Brizuela EG, Hernández CE, Bayarre H, et al. Chronic Kidney Disease and Associated Risk Factors in the Bajo Lempa Region of El Salvador: Nefrolempa Study, 2009). MEDICC Rev. 2011;13(4):14-22.