Sexual behavioural correlates of herpes simplex virus type 2 infections among pregnant women in South-western Nigeria

Authors

  • Chinenye G. Anaedobe Department of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Oyo State, Nigeria. Department of Medical Microbiology and Parasitology, College of Health Sciences, University of Abuja, FCT, Nigeria
  • Tinuade A. Ajani Department of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Oyo State, Nigeria. Department of Medical Microbiology and Parasitology, Babcock University teaching Hospital, Ilisan -Remo, Ogun State, Nigeria

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20181202

Keywords:

HSV-2, Pregnant women, Sexual risk behaviour, Vertical transmission

Abstract

Background: Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcer disease. It leads to lifelong latent infection and this raises concerns among women of reproductive age, considering the risk of neonatal transmission. This study was undertaken to identify the sexual behavioural correlates of HSV-2 infection as well as negative pregnancy outcomes.

Methods: The cross-sectional study was conducted between March and August 2013, in the antenatal clinic of the University College Hospital Ibadan. A total of 270 pregnant women aged 20 to 44 years were enrolled and their serum samples were tested for HSV-2 IgG using type specific third generation ELISA (DIAPRO Milano Italy). Pretested validated questionnaire were used to obtain bio-data, sexual behaviour and obstetrics history of the participants. Data analyses was done using SPSS version 20.

Results: The seroprevalence of HSV-2 type specific IgG was 33.3% (90/270). Logistic regression analysis showed that multiple lifetime sexual partners, early age at sexual debut, previous history of sexually transmitted infections (STIs) and having spouses whose work keep them away from home, were independent risk factors for HSV-2 infection. Obstetrics complications such as intrauterine foetal death, congenital malformations and spontaneous abortion were also strongly associated.

Conclusions: The predictors of HSV-2 infection in this study may be important in selecting candidates for screening tests and developing strategies towards effective health promotion campaign.

Author Biographies

Chinenye G. Anaedobe, Department of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Oyo State, Nigeria. Department of Medical Microbiology and Parasitology, College of Health Sciences, University of Abuja, FCT, Nigeria

Chinenye is a faculty in the Department of Medical Microbiology and Parasitology, University of Abuja and a clinical microbiologist in the affiliated University of Abuja Teaching Hospital. Her interest revolves around epidemiology of HIV, other Sexually Transmitted infections and translational research.

Tinuade A. Ajani, Department of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Oyo State, Nigeria. Department of Medical Microbiology and Parasitology, Babcock University teaching Hospital, Ilisan -Remo, Ogun State, Nigeria

She is a Consultant Clinical Microbiologist in the Department of Medical Microbiology and Parasitology, Babcock University teaching
Hospital. Ilisan -Remo, Ogun State, Nigeria She is involved in the Diagnosis and management of infectious diseases and runs a special treatment clinic where she attends to patients with Sexually transmitted infections.

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Published

2018-03-23

How to Cite

Anaedobe, C. G., & Ajani, T. A. (2018). Sexual behavioural correlates of herpes simplex virus type 2 infections among pregnant women in South-western Nigeria. International Journal Of Community Medicine And Public Health, 5(4), 1274–1280. https://doi.org/10.18203/2394-6040.ijcmph20181202

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Original Research Articles