Osteoarthritis of knee and factors associated with it in middle aged women in a rural area of central Kerala, India
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20163385Keywords:
Osteoarthritis knee, Prevalence, Kerala, Risk factorsAbstract
Background: Osteoarthritis is the fourth leading cause of years lived with disability around the world. Prevalence of osteoarthritis is more in females compared to males. Objective of the study is to find out the prevalence of osteoarthritis of knee in middle aged women and factors associated with it.
Methods: A cross -sectional study was conducted in ward 16 of Ettumanoor panchayat. A total of 375 women above 40 years were included in the study. The data was collected at their residences using a semi structured interview schedule which include demographic details and various factors associated with osteoarthritis. Weight, height, waist circumference were measured and knee joint examination was done. Data analyzed by SPSS version 19.0.The factors that were found to have a statistical significant relationship with osteoarthritis were analyzed using logistic regression.
Results: The prevalence of knee osteoarthritis in the study sample was 41.6% (95% CI- 41.6±1.25%). Among them 66.2% have bilateral osteoarthritis of knee joint. The factors that had a significant association with osteoarthritis were increasing age (p value of 0.001(OR=2.47(1.61-3.79), attained menopause or not (p value of 0.001(OR=3.15(1.96-5.06), underwent hysterectomy or not (p value of 0.038) (OR=2(1.02-4.04), family history of osteoarthritis (p value of 0.035 (OR=1.61(1.04-2.61), BMI>30 ( p value of 0.027(OR=1.86 (1.03-3.33), and history of trauma to the knee joint (p value of 0.042 (OR=1.51(0.88-2.59).
Conclusions: The prevalence of knee osteoarthritis in the study was 41.6% and the factors associated with knee osteoarthritis as per the study were increasing age, attainment of menopause, hysterectomy, family history of osteoarthritis, BMI>30 and history of trauma to the knee joint.Metrics
References
Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bulletin of the World Health Organization. 2003;81(9):646–56.
Salve H, Gupta V, Palanivel C, Yadav K, Singh B. Prevalence of knee osteoarthritis amongst perimenopausal women in an urban resettlement colony in South Delhi. Indian J Public Health. 2010;54:155-7.
Ganvir SD, Zambare BR. Prevalence and Identification of Risk Factors for Knee Osteoarthritis among Elderly Men and Women. SJAMS. 2013;1(6):700-3.
Handout on Health. Osteoarthritis, National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/health_info/Osteoarthritis/default.asp. Accessed on 20 July 2016.
Dasgupta D, Ray S. Menopausal Problems Among Rural and Urban Women From Eastern India. Journal of Social Behavioral and Health Sciences. 2009;3(1):20–33.
Dratva J, Gómez Real F, Schindler C, Ackermann-Liebrich U, Gerbase MW, Probst-Hensch NM, et al. Age at menopause increasing across Europe? Results on age at menopause and determinants from two population-based studies. Menopause. 2009;16(2):385-94
Mahajan A, Tandon V, Verma S, Sharma S. Osteoarthritis and menopause. J Indian Rheumatol Assoc. 2005:13:21-5.
Roman-Blas JA, Castaneda S, Largo R, Herrero-Beaumon G. Osteoarthritis associated with estrogen deficiency. Arthritis Research & Therapy. 2009;11:241.
Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, et al. Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors. Ann Intern Med. 2000;133(8):635-46.
Joshi K, Kumar R, Avasthi A. Morbidity profile and its relationship with disability and psychological distress among elderly people in Northern India. Int J Epidemiology. 2003;32(6):978-87.
Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 1986;29(8):1039-49.
Kerala Population Census data 2011. http://www.census2011.co.in/census/state/kerala.html. Accessed on 25 June 2016.
Ajit NE, Nandish B, Fernandes RJ, Roga G, Kasthuri A, Shanbhag DN, et al. Prevalence of knee osteoarthritis in rural areas of Bangalore urban district. Internet J Rheumatology and Clinical Immunology. 2013;1(1):1-8.
Sharma MK, Swami HM, Bhatia V, Verma A, Bhatia SPS, G Kaur. An Epidemiological Study of Correlates of Osteo-Arthritis in Geriatric Population of UT Chandigarh. 2007;32(1)77-8.
Zhang W, Doherty M, Peat G, Bierma-Zeinstra MA, Arden NK, Bresnihan B, et al. EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis. Ann Rheum Dis. 2010;69(3):483-9
Felson DT, Naimark A, Anderson J, Kazis L, Castelli W, Meenan RF. The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum. 1987;30(8):914-8.
Jordan JM, Helmick CG, Renner JB, Luta G, Dragomir AD, Woodard J, et al. Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project. J Rheumatol. 2007;34(1):172-80.
Anderson S, Loeser RF. Why is Osteoarthritis an Age-Related Disease?. Best Pract Res Clin Rheumatol. 2010;24(1): 15.
Spector TD, Brown GC, Silman AJ. Increased rates of previous hysterectomy and gynaecological operations in women with osteoarthritis, BMJ. 1988;297:8
Inoue K, Ushiyama T, Kim Y, Shichikawa K, Nishioka J, Hukuda S. Increased rate of hysterectomy in women undergoing surgery for osteoarthritis of the knee. OARS. 1995;3(3):205-9.
Spector TD, Mac-Gregor AJ. Osteoarthritis and Cartilage. Risk factors for osteoarthritis. Genetics. 2004;12:39-44.
Ellam J, Berenbaum F. Osteoarthritis and obesity. Rev Prat. 2012;62(5):621-4.
Coggon D, Reading I, Croft P, McLaren M, Barrett D, Cooper C. Knee osteoarthritis and obesity. International Journal of Obesity & Related Metabolic Disorders. 2001;25(5):622-6.
Gelber AC, Hochberg MC, Mead LA, Wang NY, Wigley FM, Klag MJ. Joint Injury in Young Adults and Risk for Subsequent Knee and Hip Osteoarthritis. Intern Med. 2000;133(5):321-8.