Comparing the risk factors of coronary artery diseases in patients with stenotic and ectatic lesions
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20175313Keywords:
Ectatic vascular lesions, Stenotic vascular lesions, Coronary artery diseaseAbstract
Background: Coronary artery ectatic usually have relation with hyperlipidemia, systemic hypertension and male gender and its diagnosis done by angiography. Due to lack of proved risk factors for incidence of coronary artery ectatic lesions and also its important. The aim of this study was to compare the risk factors of coronary artery in patients with ectatic and stenotic lesions.
Methods: This is a descriptive and analytical study that has been done on 300 patients hospitalized in Ardabil city hospital. Patients were enrolled according to the criteria and undergone to angiography. According to result of angiography, patients who have ectatic lesions as the first group and patients whose lesions were stenotic were named as the second group. Information obtained from patients entered in the checklist and analyzed by statistical methods in SPSS.16.
Results: 22% of patients with ectatic lesions and 78% with stenotic lesions in patients with ectatic lesions. The mean age was 58.7 years and 74.2% were male and in patients with lesions stenotic the mean age was 60.7 years and 54.3% were male. Based on angiography results, in patients with ectatic lesions 42.4% have engaged in a carotid and 44.4% were two clashes coronary arteries in group stenotic. 34.7% of patients have history of previous mi, 32.9% history of coronary artery disease, 54.7% history of smoking, 56% had diabetes mellitus and 56% had hypertension. History of previous MI (p=0.028), smoking (p=0.04) and diabetes mellitus (p=0.001) and history of coronary artery disease are effective risk factors in two groups.
Conclusions: The results showed that previous history of myocardial infarction, smoking and DM have significant relation with type of lesions.
References
Viles-Gonzalez JF, Fuster V, Badimon JJ. Atherothrombosis: a widespread disease with unpredictable and life-threatening consequences. Eur Heart J. 2004;25(14):1197-207.
Falk E. Pathogenesis of atherosclerosis. J Am Coll Cardiol. 2006;47(8):7-12.
Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. 1993.
Chia HM, Tan KH, Jackson G. Non-atherosclerotic coronary artery aneurysms: two case reports. Heart. 1997;78(6):613-6.
Fineschi M, Gori T, Sinicropi G, Bravi A. Polytetrafluoroethylene (PTFE) covered stents for the treatment of coronary artery aneurysms. Heart. 2004;90(5):490.
Türkay C, Gölbaşi Il, Şahin N, Kabukcu M, Bayezid Ö. Surgical management of an atherosclerotic aneurysm of the left main coronary artery. J Thoracic Cardiovascular Surg. 2001;122(3):626-7.
Association AH. Heart disease and stroke statistics—2004 update. Dallas, Texas: American Heart Association, 2003. Heart Dis Stroke. 2005.
Bassan R, Brian Gibler W. Chest pain units: state of the art of the management of patients with chest pain in the emergency department. Revista Española de Cardiología. 2001;54(09):1103.
Bolooki MBT. Acute myocardial infarction. Available at: http://www.clevelandclinic-meded com/medicalpubs/diseasemanagement/cardiology/ acute infarction. Accessed on 01 October 2009.
M. N. The picture of death in 18 provinces of Iran in 2001. Iran Ministry of Health and Medical Educations publication; 2003:123.
Lusis AJ. Atherosclerosis. Nature. 2000: 233–41.
Amirzadegan AR, Davoodi G, Soleimani A, Tokaldany ML, Kazazi EH, Shabpiray H, et al. Association between traditional risk factors and coronary artery Ectasia: a study on 10057 angiographic procedures among iranian population. J Tehran University Heart Center. 2014;9(1):27.
Bermúdez EP, Palop RL, Martínez-Luengas IL, Sánchez RC, Sáez PC, Carreras RR, et al. Coronary Ectasia: prevalence, and clinical and angiographic characteristics. Revista Espanola De Cardiologia. 2003;56(5):473-9.
Lam C, Ho K. Coronary artery Ectasia: a ten-year experience in a tertiary hospital in Singapore. Annals-Academy Med Singapore. 2004;33(4):419-22.
Giannoglou GD, Antoniadis AP, Chatzizisis YS, Damvopoulou E, Parcharidis GE, Louridas GE. Prevalence of Ectasia in human coronary arteries in patients in northern Greece referred for coronary angiography. Am J Cardiol. 2006;98(3):314-8.
Sharma S, Kaul U, Sharma S, Wasir H, Manchanda S, Bahl V, et al. Coronary arteriographic profile in young and old Indian patients with ischaemic heart disease: a comparative study. Indian Heart J. 1989;42(5):365-9.
Yilmaz H, Sayar N, Yilmaz M, Tangürek B, Cakmak N, Gürkan U, et al. Coronary artery Ectasia: clinical and angiographical evaluation. Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir. 2008;36(8):530-5.
Demopoulos VP, Olympios CD, Fakiolas CN, Pissimissis EG, Economides NM, Adamopoulou E, et al. The natural history of aneurysmal coronary artery disease. Heart. 1997;78(2):136-41.
Hosseini SK, Soleimani A, Salarifar M, Pourhoseini H, Nematipoor E, Abbasi SH, et al. Demographics and angiographic findings in patients under 35 years of age with acute ST elevation myocardial infarction. J Tehran University Heart Center. 2011;6(2):62-7.
Zeina A-R, Sharif D, Blinder J, Rosenschein U, Barmeir E. Noninvasive assessment of coronary artery Ectasia using multidetector computed tomography. Coronary Artery Disease. 2007;18(3):175-80.
Sudhir K, Ports TA, Amidon TM, Goldberger JJ, Bhushan V, Kane JP, et al. Increased prevalence of coronary Ectasia in heterozygous familial hypercholesterolemia. Circulation. 1995;91(5):1375-80.
Williams SB, Cusco JA, Roddy M-A, Johnstone MT, Creager MA. Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J Am Coll Cardiol. 1996;27(3):567-74.
Nyamu P, Ajit MS, Joseph PK, Venkitachalam L, Sugirtham NA. The prevalence and clinical profile of angiographic coronary Ectasia. Asian Cardiovascular and Thoracic Annals. 2003;11(2):122-6.
