Study on the impact of family history of diabetes among type 2 diabetes mellitus patients in an urban area of Kancheepuram district, Tamil Nadu
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20174819Keywords:
Age of onset, Diabetic mother, Diabetic father, T2DMAbstract
Background: Type 2 diabetes mellitus (T2DM) is a commonly occurring chronic non communicable disease. Family history of diabetes is one of the important non modifiable risk factor for occurrence of the disease. This study was done to assess the percentage of positive family history of diabetes among T2DM patients and its association with age of onset and complications of diabetes.
Methods: This is a descriptive cross sectional study done in an urban health training centre of a medical college. Using purposive sampling technique, 215 diabetic patients were selected as study participants. Data collection was done by structured questionnaire. Data analysis was done using SPSS 17.
Results: Among the study participants, 62.3% were females. The mean age of the participants was 56.08±10.04. Nearly 68.8% of T2DM patients had family history of Diabetes, among them 25.1% of them had diabetic mother and 15.3% had diabetic father. Among the study group of T2DM patients, 51.6% had diabetic complications. The family history of diabetes with age of onset and complications had statistically significant association among the study group.
Conclusions: This study shows that persons with positive family history of diabetes are more prone to early onset of diabetes and developing complications. So appropriate behavioural changes and modification must be practiced to delay or prevent the occurrence of the disease. Early diagnosis and treatment is a must to prevent the complications in the vulnerable people.
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References
World Health Organization. Diabetes. Available at http://www.who.int/diabetes/en/. Accessed on 20 August 2017.
World Health Organization. Diabetes fact sheets. Updated July 2017. Available at http://www.who.int /mediacentre/factsheets/fs312/en/. Accessed on 20 August 2017.
American Heart Association. Understand your risk for Diabetes. Available at http://www.heart.org/ HEARTORG/Conditions/More/Diabetes/UnderstandYourRiskforDiabetes/Understand-Your-Risk-for-Diabetes_UCM_002034_Article.jsp#.WZxri1UjHIV. Accessed on 20 August 2017.
Keku TO, Millikan RC, Martin C, Rahkra-Burris TK, Sandler RS. Family history of colon cancer: what does it mean and how is it useful? Am J Prev Med. 2003;24(2):170-6.
World Health Organization. Global report on Diabetes. p13. Available at http://apps.who.int/iris/ bitstream/10665/204871/1/9789241565257_eng.pdf. Accessed on 31 July 2017.
World Health Organization. World Health Day 2016: Diabetes. Available at http://www.searo. who.int/india/mediacentre/events/2016/en/. Accessed on 18 August 2017.
Dhananjayan R, Malati T, Brindha G, Kutala VK. Association of family history of type 2 diabetes mellitus with markers of endothelial dysfunction in South Indian population. Indian J Biochem Biophys. 2013;50(2):93-8.
Ramachandran A. Epidemiology of type 2 diabetes in India. J Indian Med Assoc. 2002;100:425–7.
Klein BE, Klein R, Moss SE, Cruickshanks KJ. Parental history of diabetes in a population-based study. Diabetes Care. 1996;19(8):827-30.
Alcolado JC, Alcolado R. Importance of maternal history of non-insulin dependent diabetic patients. BMJ. 1991;302(6786):1178-80.
Diabetes.co.k. Diabetes and genetics. Available at http://www.diabetes.co.uk/diabetes-and-genetics.html. Accessed on 20 August 2017.
Vishwanathan M, McCarthy MI, Snehalatha C, et al. Aggregation of type 2 (non-insulin-dependent) diabetes mellitus in South India; Absence of excess maternal transmission. Diabet Med. 1996;13(3):232-7.
Moleneaux L, Constantino M, Yue D. Strong family history predicts a younger age of onset for subjects diagnosed with type 2 diabetes. Diabetes Obes Metab. 2004;6(3):187-94.
Bo S, Cavallo-Perin P, Gentile L, Repetti E, Pagano G. Influence of a familial history of diabetes on the clinical characteristics of patients with type 2 diabetes mellitus. Diabet Med. 2000;17(7):538-42.
Baptiste-Roberts K, Gary TL, Beckles GL, Gregg EW, Owens M, Porterfield D, et al. Family history of diabetes, awareness of risk factors, and health behaviors among African Americans. Am J Public Health. 2007;97(5):907-12.
Srikanth E. Familial Aggregation of Type 2 Diabetes Mellitus in Rural India. IJSR. 2015:4(8):41-5.
Patel M, Patel IM, Patel YM, Rathi SK. A hospital-based observational study of type 2 diabetic subjects from India. Int J Clin Pract. 2013;24(2):141-8.
Crispim D, Canani LH, Gross JL, Tschiedel B, Souto KE, Roisenberg I. Familial history of type 2 diabetes in patients from Southern Brazil and its influence on the clinical characteristics of this disease. Arq Bras Endocrinol Metab. 2006;50(5):862-8.
Jali MV, Kambar S, Jali SM, Gowda S. Familial early onset of type-2 diabetes mellitus and its complications. N Am J Med Sci. 2009;1(7):377-80.
Papazafiropoulou A, Sotiropoulos A, Skliros E, Kardara M, Kokolaki A, Apostolou O, Pappas S. Familial history of diabetes and clinical characteristics in Greek subjects with type 2 diabetes. BMC Endocr Disord. 2009;9(1):12-8.