Dengue fever and its epidemiological characteristics: a study from Eastern India

Sudeb Mukherjee; Kaushik Manna; Pritam Chatterjee; Pramathanath Datta; Suhana Datta

doi:10.18203/2394-6040.ijcmph20164297

Authors

Sudeb Mukherjee Department of Cardiology, IPGME & R, Kolkata, West Bengal
Kaushik Manna Deprtment of Cardiology, CNMCH, Kolkata, West Bengal, India
Pritam Chatterjee Deprtment of Cardiology, CNMCH, Kolkata, West Bengal, India
Pramathanath Datta Department of Surgery, KPC Medical College, Kolkata, West Bengal, India
Suhana Datta Regional Institute of Ophthalmology, CMCH, Kolkata, West Bengal, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20164297

Keywords:

DF, DHF, DSS, LFT, Platelet count

Abstract

Background: Dengue fever (DF) has become a major global public health problem. In India, epidemics are becoming more frequent. Dengue infection ranges from mild illness to a severe form of haemorrhagic fever and shock syndrome which may prove fatal. Early recognition and meticulous management are very important to save precious lives from this killer disease.

Methods: Total 82 patients (63 male, 19 female) admitted with diagnosis of dengue fever were analysed in details from clinical features to outcomes.

Results: Fever was the most consistent symptoms. Biochemical abnormalities in liver function test were very evident. Bleeding manifestations has no correlation with platelet count. Platelet transfusion was needed in very few patients.

Conclusions: High suspicion, early investigations and diagnosis is very important to prevent fatal complications of dengue fever and adequate hydration is one of the most effective treatments.

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References

Ananthnarayan R, Panikar CKJ. In Ananthanarayan and Paniker’s Textbook of Microbiology, 7th ed. Hyderabad: Orient Longman; 2005:pg 521-34.

WHO/EMRO. World Health Organization, Regional Office for the Eastern Mediterranean, Division of Communicable Disease Control, Newsletter, I2005, 6:7–8. (http://www.emro.who.int/ pdf/ dcdnewsletter6. pdf).

Dengue haemorrhagic fever: diagnosis, treatment, prevention and control. New edition. World Health Organization. 2009.

Guzman MG, Halstead SB, Artsob H, Buchy P, Farrar J, Gubler DJ, et al. Dengue: a continuing global threat. Nat Rev Microbiol. 2010;8(12 Suppl):S7-16.

Dengue fever and dengue haemorrhagic fever prevention and control. World Health Assembly Resolution WHA 55.17, adopted by the 55th World Health Assembly, 2002. (http://www.who.int/gb/ ebwha/pdf_files/WHA55/ewha5517.pdf).

WHO. Revision of the International Health Regulations. World Health Assembly Resolution WHA58.3, adopted by the 58th World Health Assembly, 2005 (http://www.who.int/gb/ ebwha/pdf_files/WHA58/WHA58_3-en.pdf).

Malavige GN, Fernando S, Fernando DJ, Seneviratne SL. Dengue viral infections. Postgrad Med J. 2004;80:588-601.

Singh NP, Jhamb R, Agarwal SK, Gaiha M, Dewan R, Daga MK, et al. The 2003 Outbreak of Dengue fever in Delhi, India. Southeast Asian J Trop Med Public Health. 2005;36:1174-8.

Naraynan M, Aravind MA, Thilothammal N, Prema R, Sargunam CS, Ramamurty N. Dengue fever epidemic in Chennai-a study of clinical presentation and outcome. Indian Pediatr. 2002;39:1027-33.

Gomber S, Ramachandran VG, Kumar S, Agarwal, Gupta P, Gupta P et al Hematological observations as diagnostic markers in dengue hemorrhagic fever –a reappraisal. Indian Pediatr. 2001;38:477-81.

Anuradha S, Singh NP, Rizvi SN, Agarwal SK, Gur R, Mathur MD. The 1996 outbreak of dengue hemorrhagic fever in Delhi, India. Southeast Asian J Trop Med Public Health. 1998;29:503-6.

Guha-Sapir D, Schimmer B. Dengue fever: new paradigm for a changing epidemiology. Emerg Themes Epidemiol 2005;2:1 (http://www.ete-online.com/content/2/1/1).

Rahman M, Rahman K, Siddque AK, Shoma S, Kamal AH, Ali KS et al. First outbreak of Dengue hemorrhagic fever, Bangladesh. Emerg Infect Dis. 2002;8:738-40.

Martinez-Torres E, Polanco-Anaya AC, Pleites-Sandoval EB. Why and how children with dengue die? Revista cubana de medicina tropical. 2008;60(1):40-7.

Guzman MG, Kouri G, Valdes L, Bravo J, Alvarez M, Vazques S et al. Epidemiologic studies on dengue in Santiago de Cuba, 1997. American J Epidemiology. 2000;152(9):793-9.

Sharma S, Sharma SK, Mohan A, Wadhwa J, Dar L. Clinical presentation of Dengue Haemorrhagic Fever in Adults during 1996-Outbreak in Delhi, India. Dengue Bulletin. 1998;22:20-30.

Kuo CH, Tai DI, Chang-Chien CS, Lan CK, Chiou SS, Liaw YF. Liver biochemical tests and Dengue fever. Am J Trop Med Hyg. 1992; 47: 265-70.

Mohan B, Patwari AK, Anand VK. Hepatic dysfunction in childhood Dengue infection. J Trop Pediatr. 2000;46:40-3.

Sa-Ngasang A, Anantapreecha S, A-Nuegoonpipat A, Chanama S, Wibulwattanakij S, Pattanakul K et al. Specific IgM and IgG responses in primary and secondary dengue virus infections determined by enzyme-linked immunosorbent assay. Epidemiol Infect. 2006;134(4):820-5.

Kuno G, Gomez I, Gubler DJ. An ELISA procedure for the diagnosis of dengue infections. J Virol Methods. 1991;33(1-2):101-13.

Shu PY, Chen LK, Chang S F, Yueh YY, Chow L, Chien LJ et al. Comparison of a capture immunoglobulin M (IgM) and IgG ELISA and non-structural protein NS1 serotype-specific IgG ELISA for differentiation of primary and secondary dengue virus infections. Clinical and Diagnostic Laboratory Immunology. 2003:10:622-30.