Dietary factors and associated health effects among patients with vitamin D deficiency

Maisha Mehjabin; Momena Shirin; M. Abiduzzaman

doi:10.18203/2394-6040.ijcmph20263156

Authors

Maisha Mehjabin Faculty of Medicine, MAHSA University, Bandar Saujana Putra, Malaysia
Momena Shirin Food Chemistry Department, Institute of Public Health Nutrition, Dhaka, Bangladesh
M. Abiduzzaman Faculty of Business, MAHSA University, Bandar Saujana Putra, Malaysia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20263156

Keywords:

Association, Dietary habits, Health problems, Supplements, Vitamin D deficiency

Abstract

Background: Vitamin D deficiency is prevalent among men and women alike and is often left untreated in developing countries. Vitamin D deficiency and its associated health problems can be controlled if dietary intake is properly maintained. The study objective was to understand the dietary habits and the problems faced by patients of a hospital in Dhaka due to vitamin D deficiency.

Methods: Total 133 patients were selected through convenience sampling, and their vitamin D levels were collected from the medical records. Other data were collected from a previously set questionnaire.

Results: Total 56 (42.1%) were men, and 77 (57.9%) were women among the patients. 42 (31.6%) of the vitamin D-deficient people were obese in this study. 17 (12.8%) people still had severe (level <12 ng/ml) vitamin D deficiency even after receiving treatment and needed more. The egg and meat intake among the participants was satisfactory, but milk intake was low among them. 88 (66.1%) patients took vitamin D supplements at the time of study. However, there is no significant association between dietary intake and vitamin D deficiency. Vitamin D status is associated with chronic health problems, such as hypertension and diabetes mellitus, as well as with the intake of vitamin D and calcium supplements (p<0.05). Bone pain, joint pain, hair fall, anxiety, depression, etc., were some of the problems that the patients faced before receiving treatment.

Conclusions: Those who are suffering from vitamin D deficiency should get their bodies checked regularly to diagnose the associated diseases.

References

Pludowski P, Holick MF, Grant WB, Konstantynowicz J, Mascarenhas MR, Haq A, Povoroznyuk V, Balatska N, et al. Vitamin D supplementation guidelines. J Steroid Biochem Mol Biol. 2018;175:125-35.

Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. In: Feingold K, Anawalt B, and Boyce A, editors. Chemical Biology. South Dartmouth, MA: Endotext; 2021;319-29.

Palacios C, Gonzalez L. Is vitamin D deficiency a major global public health problem? J Steroid Biochem Mol Biol. 2014;144:138-45.

Czernichow S, Fan T, Nocea G, Sen SS. Calcium and vitamin D intake by postmenopausal women with osteoporosis in France. Curr Med Res Opin. 2010;26(7):1667-74.

amy AlHetar M, Mahfoudh AM, Baobaid MF, Ruhi S. Prevalence, predictors, and gender-based risk factors of vitamin D deficiency: a retrospective cross-sectional study. J Angiother. 2024;8(11):1-9.

Polzonetti V, Pucciarelli S, Vincenzetti S, Polidori P. Dietary intake of vitamin D from dairy products reduces the risk of osteoporosis. Nutrients. 2020;12(6):1743.

Dix CF, Bauer JD, Martin I, Rochester S, Duarte Romero B, Prins JB, et al. Association of sun exposure, skin colour and body mass index with vitamin D status in individuals who are morbidly obese. Nutrients. 2017;9(10):1094.

Kaur J, Khare S, Sizar. Vitamin D Deficiency. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025.

Wang H, Chen W, Li D, Yin X, Zhang X, Olsen N, et al. Vitamin D and chronic diseases. Aging Dis. 2017;8(3):346-53.

Siddiqee MH, Bhattacharjee B, Siddiqi UR, Meshbahur Rahman M. High prevalence of vitamin D deficiency among the South Asian adults: a systematic review and meta-analysis. BMC Publ Heal. 2021;21(1):1823.

Altowijri A, Alloubani A, Abdulhafiz I, Saleh A. Impact of nutritional and environmental factors on Vitamin D deficiency. Asian Pac J Cancer Prev. 2018;19(9):2569-74.

Gill S, Adenan AM, Thomas EE, Haleelur Rahman A, Rahim NBA, Ismail NAS. Beyond the tropics: unraveling the complex relationship between Sun exposure, dietary intake, and vitamin D deficiency in Coastal Malaysians. Nutrients. 2024; 16(6):830.

Wang Y, Hu C, Li Y, Liu Q, Gao L, Zhang D, Cao L. Association between serum vitamin D and the risk of diabetic kidney disease in patients with type 2 diabetes. Front Med (Lausanne). 2024;11:1445487.

Islam MZ, Bhuiyan NH, Akhtaruzzaman M, Allardt CL, Fogelholm M. Vitamin D deficiency in Bangladesh: A review of prevalence, causes and recommendations for mitigation. Asia Pac J Clin Nutr. 2022;31(2):167-80.

Priyanka AS, Progga TT, Nasher S. Comparison of vitamin D status in healthy Bangladeshi urban and rural individuals and their association with serum calcium and alkaline phosphatase: A pilot study. Nutrition Bullet. 2024;50(1):82-90.

Mozos I, Marginean O. Links between vitamin D deficiency and cardiovascular diseases. Biomed Res Int. 2015;2015:109275.

Płudowski P, Kos-Kudła B, Walczak M, Fal A, Zozulińska-Ziółkiewicz D, Sieroszewski P, et al. Guidelines for Preventing and Treating Vitamin D Deficiency: A 2023 Update in Poland. Nutrients. 2023;15(3):695.

Holick MF. Evidence-based D-bate on health benefits of vitamin D revisited. Dermatoendocrinol. 2012;4(2):183-90.

Office of Dietary Supplements. Fact Sheet: Vitamin D, 2025. Available at: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/. Accessed 01 January 2026.

Alam S, Siam MM, Khan MA, Islam N, Rahman MM, Kabi SS, et al. Vitamin D Deficiency and its Clinical Implications in Adults. SAS J Med. 2025;11(9): 886-91.

Martyn K. Understanding nutrition research for better patient care. BMJ Nutr Prev Heal. 2025;8(1):e001241.