Isolation and its impact on quality of life at end-of-life palliative care services

Authors

  • Weam Ahmed Mohammed Mari Department of Hospital Management and Hospice Studies, Jamia Millia Islamia, New Delhi, India
  • Pooja Sharma Department of Hospital Management and Hospice Studies, Jamia Millia Islamia, New Delhi, India https://orcid.org/0000-0001-6380-2455

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20262241

Keywords:

End-of-Life care, Terminally ill patients, Social isolation, Quality of life, Psychological wellness, Hospice care, Palliative care

Abstract

Background: Palliative care seeks to provide terminally ill individuals with an improved quality of life, preserved dignity, and increased overall well-being; however, social isolation is one of the most significant and frequently overlooked issues associated in end-of-life care settings. Social isolation has become a growing challenge to global health systems and poses significant psychological and physiological consequences for individuals at the end of life.

Methods: An extensive peer-reviewed literature review was conducted to examine the relationship between social isolation and quality of life among patients receiving palliative and hospice care, using article databases, policy and governmental review documents, and international public health reports published between 2010 and 2024.

Results: Results show social isolation as a significant but least acknowledged impact of terminal illness on quality of life for patients in palliative care. Research indicates that socially isolated terminally ill patients report higher levels of anxiety, depression, and emotional distress, as well as poorer physical and psychological outcomes than those who are not isolated. This review highlighted the importance of developing effective interventions that address patients’ psychosocial, emotional, and spiritual needs to improve QoL and overall well-being in palliative care.

Conclusions: The influence of social isolation on the QoL and overall well-being of terminally ill patients receiving palliative care should be recognized as an important factor impacting patient-oriented outcomes in the provision of comprehensive palliative care through targeted interventions designed to support these needs.

References

McCaffrey N, Ratcliffe J, Currow D, Engel L, Hutchinson C. What aspects of quality of life are important from palliative care patients’ perspectives? A framework analysis to inform preference-based measures for palliative and end-of-life settings. Patient. 2024;17(1):39-52.‏

Macharia JM, Raposa BL, Sipos D, Melczer C, Toth Z, Kaposztas Z. The impact of palliative care on mitigating pain and its associated effects in determining quality of life among colon cancer outpatients. Healthcare. 2023;11(22):2954.‏

Fox RS, Armstrong GE, Gaumond JS, Vigoureux TF, Miller CH, Sanford SD, et al. Social isolation and social connectedness among young adult cancer survivors: a systematic review. Cancer, 2023;129(19):2946-65.‏

Sadowska K, Fong T, Horning DR, McAteer S, Ekwebelem MI, Demetres M, et al. Psychiatric comorbidities and outcomes in palliative and end-of-life care: a systematic review. J Pain Symptom Manage. 2023;66(1):e129-51.‏

Keen A, Deike L, Haan J. Combatting social isolation, anxiety, and loneliness in hospitalized patients: a quasi-experimental study. J Nurs Admin. 2023;53(7/8):385-91.‏

Hanna JR, McConnell T, Harrison C, Patynowska KA, Finucane AM, Hudson B, et al. ‘There’s something about admitting that you are lonely’- prevalence, impact and solutions to loneliness in terminal illness: An explanatory sequential multi-methods study. Palliat Med. 2022;36(10):1483-92.‏

Hunt J, Bristowe K, Chidyamatare S, Harding R. ‘So isolation comes in, discrimination and you find many people dying quietly without any family support’: Accessing palliative care for key populations–an in-depth qualitative study. Palliative medicine, 2019;33(6):685-92.‏

Giammalva GR, Iacopino DG, Azzarello G, Gaggiotti C, Graziano F, Gulì C, et al. End-of-life care in high-grade glioma patients. The palliative and supportive perspective. Brain Sci. 2018;8(7):125.‏

Pivodic L, Van den Block L, Pivodic F. Social connection and end-of-life outcomes among older people in 19 countries: a population-based longitudinal study. Lancet Healthy Long. 2024;5(4):e264-e75.‏

Holt‐Lunstad J. Social connection as a critical factor for mental and physical health: evidence, trends, challenges, and future implications. World Psychiatr. 2024;23(3):312-32.‏

Cagle JG, Bunting M, Kelemen A, Lee J, Terry D, Harris R. Psychosocial needs and interventions for heart failure patients and families receiving palliative care support: a systematic review. Heart Fail Rev. 2017;22(5):565-80.‏

Jaiswal R, Alici Y, Breitbart W. A comprehensive review of palliative care in patients with cancer. Int Rev Psychiatr. 2014;26(1):87-101.‏

Götze H, Brähler E, Gansera L, Polze N, Köhler N. Psychological distress and quality of life of palliative cancer patients and their caring relatives during home care. Support Care Cancer. 2014;22(10):2775-82.‏

Bradt J, Dileo C. Music therapy for end‐of‐life care. Cochrane Database Syst Rev. 2010;2010(1).‏

Erdoğan TK, Koç Z. Loneliness, death perception, and spiritual well-being in adult oncology patients. Cancer Nurs. 2021;44(6):E503-12.‏

Lee GL, Ramaswamy A. Physical, psychological, social, and spiritual aspects of end-of-life trajectory among patients with advanced cancer: a phenomenological inquiry. Death Stud. 2020.

Balducci L. Geriatric oncology, spirituality, and palliative care. J Pain Sympt Manage. 2019;57(1):171-5.‏

Götze H, Ernst J, Brähler E, Romer G, von Klitzing K. Predictors of quality of life of cancer patients, their children, and partners. Psycho‐Oncol. 2015;24(7):787-95.

Downloads

Published

2026-06-30

How to Cite

Mohammed Mari, W. A., & Sharma, P. (2026). Isolation and its impact on quality of life at end-of-life palliative care services. International Journal Of Community Medicine And Public Health, 13(7), 3503–3508. https://doi.org/10.18203/2394-6040.ijcmph20262241

Issue

Section

Original Research Articles