Prevalence of radiographic osteoarthritis in an outpatient clinic at a teaching and referral hospital in Laikipia County, Kenya
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20261739Keywords:
Kenya, Laikipia county, Musculoskeletal burden, OA prevalence, Radiographic osteoarthritisAbstract
Background: Osteoarthritis (OA) is a leading cause of chronic pain and disability globally, particularly among older adults. In sub-Saharan Africa, including Kenya, OA represents a growing public health burden amid demographic transitions and lifestyle changes. Despite this, there is limited local data on its prevalence, correlates especially in rural communities. This study aimed to determine the prevalence and predictors of radiographic OA in patients at a Teaching and Referral Hospital in Laikipia.
Methods: A cross-sectional study in an orthopaedic outpatient clinic was conducted for 4 months involving 194 participants aged ≥ 18 years. Systematic random sampling was employed. Data were collected using a structured researcher-administered questionnaire for sociodemographic and clinical information. Anthropometric measurements were taken and imaging reports were reviewed to confirm OA diagnosis and severity. Descriptive statistics summarized patient characteristics. Logistic regression models identified independent predictors of OA. Informed consent and ethical approvals were obtained.
Results: The overall prevalence was 32.5% (95% CI: 26.2–39.4). OA was significantly more common among females (61.9%), older adults (mean age 62.9±13.5 years) and those with comorbidities (60.3%). Nearly half (47.6%) were obese. The knee was the most frequently affected joint. Multivariate analysis revealed that increasing age (AOR=1.094, p<0.001), obesity (AOR=6.190, p=0.008) and poor functional status (ECOG≥1) (AOR=8.393, p=0.001) were independent predictors.
Conclusions: OA is highly prevalent in this rural setting. Advanced age, obesity and functional limitations are key predicting factors. Targeted screening prioritizing older patients and mandatory assessment of obesity and functional status are essential for timely management.
References
Steinmetz JD, Culbreth GT, Haile LM, Rafferty Q, Lo J, Fukutaki KG, et al. Global, regional and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the global burden of disease study 2021. Lancet Rheumatol. 2023;5(9):508–22.
Long H, Liu Q, Yin H, Wang K, Diao N, Zhang Y, et al. Prevalence Trends of Site‐Specific Osteoarthritis From 1990 to 2019: findings from the global burden of disease study 2019. Arthritis Rheumatol. 2022;74(7):1172–83.
Turkiewicz A, Petersson IF, Björk J, Hawker G, Dahlberg LE, Lohmander LS, et al. Current and future impact of osteoarthritis on health care: a population-based study with projections to year 2032. Osteoarthr Cartil. 2014;22(11):1826–32.
Usenbo A, Kramer V, Young T, Musekiwa A. Prevalence of arthritis in Africa: a systematic review and meta-analysis. PLoS One. 2015;10(8):133858.
Kingori J, Ortho M, Surgeon CO, Hospital PK, Gakuu LN. Total hip replacements at Kikuyu Hospital, Kenya. East African Orthop J. 2010;4:44–7.
Nour H, Oyoo G, Joshi M, Otsyeno F. Patterns of knee, hip and hand osteoarthritis in Kenyatta National Hospital. EAOJ. 2014;7(1):53–6.
Nkeck JR, Ngandeu-Singwé M. Conference proceedings: 11th congress of the African league of associations for rheumatology and 4th congress of the cameroon college of rheumatology. African J Rheumatol. 2025;13(2):117-50.
Dino SY, Oyoo GO, Med T, Rheum C, Epid C, Ilovi CS. Assessment of pain severity and functional status in patients with knee osteoarthritis at the kenyatta national hospital, Nairobi, Kenya. East African Orthop J. 2023;17(2):85–91.
Mwaura HH. Outcome of non-operative treatment of patients with primary osteoarthritis of the knee at moi teaching and referral hospital , Eldoret , Kenya. Moi University. 2020.
Bija MD, Luma HN, Temfack E, Gueleko ET, Kemta F, Ngandeu M. Patterns of knee osteoarthritis in a hospital setting in sub-Saharan Africa. Clinical Rheumatol. 2015;34(11):1949-53.
Aboderin I, Nanyonjo A. Musculoskeletal health conditions among older populations in urban slums in sub-Saharan Africa. Best Pract Res Clin Rheumatol. 2017;31(2):115–28.
Kinara SN, Kimani HM, Ogweno GO. Prevalence and predictors of arthritis among adults in a rural set-up in Kenya: a cross-sectional study. Pan Afr Med J. 2024;4:864.
Kuo C, Black L, Kelly C. Arthritis in East Africa: an observational study. Afr J Rheumatol. 2023;62(2):3–9.
Hart D, Myers J, Kilonzo Sa, Wachira B, Hunold Buck K, Davis W, et al. An Epidemiologic Analysis of Nanyuki District Teaching and Referral Hospital, Laikipia, Kenya. 2018.
Dennison EM. Osteoarthritis: The importance of hormonal status in midlife women. Maturitas. 2022;165:8–11.
Peshkova M, Lychagin A, Lipina M, Di Matteo B, Anzillotti G, Ronzoni F, et al. Gender-Related Aspects in Osteoarthritis Development and Progression: A Review. Int J Mol Sci. 2022;23(5):2767.
Avila S, Hao Y, Bani-Fatemi A, Howe A, Nowrouzi-Kia B. Impacts of arthritis on work performance, functioning and activities of daily living using the Canadian community health survey. Work. 2025;81(1):2167-79.
Yunus MHM, Nordin A, Kamal H. Pathophysiological Perspective of Osteoarthritis. Medicina (B Aires). 2020;56(11):614.
Safdar A, Hamadeh MJ, Kaczor JJ, Raha S, DeBeer J, Tarnopolsky MA. Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults. PLoS One. 2010;2(5):10778.
Rakutt MJ, Mace RA, Conley CEW, Stone A V., Duncan ST, Greenberg J, et al. Association of osteoarthritis and functional limitations with cognitive impairment among older adults in the United States. J Aging Health. 2023;35(9):643–50.
He Y, Li Z, Alexander PG, Ocasio-Nieves BD, Yocum L, Lin H, et al. Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes and Experimental Models. Biology (Basel). 2020;29;9(8):194.
Lin X, Li H. Obesity: Epidemiology, Pathophysiology and Therapeutics. Front Endocrinol (Lausanne). 2021;6;12.
Muyodi M, Oyoo G, Bhatt K, Kayima J. Prevalence of and factors associated with chronic kidney disease in osteoarthritis patients at Kenyatta National Hospital. East African Orthop J EAOJ. 2020;14(2):72–80.
Cochran WG. Sampling Techniques. 3rd ed. New York: John Wiley & Sons. 1977: 74–76.
Al Saleh J, Almoallim H, Elzorkany B, Al Belooshi A, Batouk O, Fathy M, et al. Assessing the burden of osteoarthritis in Africa and the middle east: a rapid evidence assessment. Rheumatol Res Rev. 2023;15:23–32.
Pereira D, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E. The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review. Osteoarthr Cartil. 2011;19(11):1270–85.
Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA. 1995;273(1):59–65.
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