Relationship between circadian disruption and mood instability in shift workers
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20260123Keywords:
Circadian disruption, Mood instability, Shift work, Sleep regulation, ChronotypeAbstract
Shift work has become a structural necessity in modern economies, yet its impact on mental health remains a growing concern. Circadian disruption, a core consequence of working non-standard hours, has been consistently linked to mood instability. This misalignment between internal biological rhythms and externally imposed work schedules affects key physiological systems involved in emotional regulation, including sleep-wake cycles, hormonal rhythms, and neurotransmitter activity. Disturbed sleep architecture, altered cortisol patterns, and impaired serotonergic function all contribute to heightened vulnerability to mood disorders such as depression, anxiety, and emotional lability among shift workers. The relationship between circadian misalignment and mood is not uniform across individuals. Genetic predispositions, diurnal preference, social environment, and occupational conditions play a substantial role in modulating emotional outcomes. Evening chronotypes may adapt more efficiently to night shifts, while certain polymorphisms in circadian genes increase sensitivity to rhythm disruption. Social support and perceived control over work schedules further influence psychological resilience in these populations. Clinical interventions targeting circadian health have shown efficacy in improving emotional outcomes. Light therapy, melatonin, and behavioral strategies such as cognitive behavioral therapy for insomnia have demonstrated benefits in regulating both sleep and mood. Preventive measures, including forward-rotating shift schedules, extended recovery periods, and fatigue risk management systems, also contribute to mitigating psychological harm. Addressing mood instability in shift workers requires a multidimensional approach that considers biological rhythms, individual risk modifiers, and systemic workplace design.
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Wittmann M, Dinich J, Merrow M, Roenneberg T. Social jetlag: misalignment of biological and social time. Chronobiol Int. 2006;23(2):497-509. DOI: https://doi.org/10.1080/07420520500545979
Boivin DB, Boudreau P. Impacts of shift work on sleep and circadian rhythms. Pathologie Biologie. 2014;62(5):292-301. DOI: https://doi.org/10.1016/j.patbio.2014.08.001
Walker WH, Walton JC, DeVries AC, Nelson RJ. Circadian rhythm disruption and mental health. Transl Psychiat. 2020;10(1):28. DOI: https://doi.org/10.1038/s41398-020-0694-0
Vetter C, Devore EE, Wegrzyn LR. Association between rotating night shift work and risk of coronary heart disease among women. Jama. 2016;315(16):1726-34. DOI: https://doi.org/10.1001/jama.2016.4454
Kalmbach DA, Abelson JL, Arnedt JT, Zhao Z, Schubert JR, Sen S. Insomnia symptoms and short sleep predict anxiety and worry in response to stress exposure: a prospective cohort study of medical interns. Sleep Med. 2019;55:40-7. DOI: https://doi.org/10.1016/j.sleep.2018.12.001
Okechukwu CE, Colaprico C, Di Mario S. The relationship between working night shifts and depression among nurses: a systematic review and meta-analysis. Healthcare. 2023;3:869. DOI: https://doi.org/10.3390/healthcare11070937
Logan RW, Williams III WP, McClung CA. Circadian rhythms and addiction: mechanistic insights and future directions. Behav Neurosci. 2014;128(3):387. DOI: https://doi.org/10.1037/a0036268
Ruggiero JS, Redeker NS. Effects of napping on sleepiness and sleep-related performance deficits in night-shift workers: a systematic review. Biol Res Nurs. 2014;16(2):134-42. DOI: https://doi.org/10.1177/1099800413476571
Ettorre G, Pellicani V, Caroli A, Greco M. Shift work sleep disorder and job stress in shift nurses: implications for preventive interventions. La Med lav. 2020;111(3):195. DOI: https://doi.org/10.23749/mdl.v111i3.9197
Arlinghaus A, Bohle P, Iskra-Golec I, Jansen N, Jay S, Rotenberg L. Working Time Society consensus statements: Evidence-based effects of shift work and non-standard working hours on workers, family and community. Industrial Health. 2019;57(2):184-200. DOI: https://doi.org/10.2486/indhealth.SW-4
Archer SN, Robilliard DL, Skene DJ. A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep. 2003;26(4):413-5. DOI: https://doi.org/10.1093/sleep/26.4.413
Juda M, Vetter C, Roenneberg T. Chronotype modulates sleep duration, sleep quality, and social jet lag in shift-workers. J Biol Rhythms. 2013;28(2):141-51. DOI: https://doi.org/10.1177/0748730412475042
Bambra C, Whitehead M, Sowden A, Akers J, Petticrew M. “A hard day’s night?” The effects of Compressed Working Week interventions on the health and work-life balance of shift workers: a systematic review. J Epidemiol Comm Health. 2008;62(9):764-77. DOI: https://doi.org/10.1136/jech.2007.067249
14. Crowley SJ, Lee C, Tseng CY, Fogg LF, Eastman CI. Complete or partial circadian re-entrainment improves performance, alertness, and mood during night-shift work. Sleep. 2004;27(6):1077-87. DOI: https://doi.org/10.1093/sleep/27.6.1077
Liira J, Verbeek JH, Costa G. Pharmacological interventions for sleepiness and sleep disturbances caused by shift work. Cochrane Datab System Rev. 2014;8:173. DOI: https://doi.org/10.1002/14651858.CD009776.pub2
Järnefelt H, Lagerstedt R, Kajaste S, Sallinen M, Savolainen A, Hublin C. Cognitive behavior therapy for chronic insomnia in occupational health services. J Occupat Rehabil. 2012;22(4):511-21. DOI: https://doi.org/10.1007/s10926-012-9365-1
Fan C, Huang S, Lin S, Xu D, Peng Y, Yi S. Types, risk factors, consequences, and detection methods of train driver fatigue and distraction. Comput Int Neuro. 2022;2(1):8328077. DOI: https://doi.org/10.1155/2022/8328077
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