Clinico epidemiological profile and trends of breast cancer over a decade: a study from UT of J&K, India

Ashutosh  Gupta; Rajiv Kumar Gupta; Rahul Sharma; Rashmi Kumari; Sandeep Kour; Swarn Singh Katoch; Rajeev Gupta; Aproo Sharma

doi:10.18203/2394-6040.ijcmph20260305

Authors

Ashutosh Gupta Government Medical College, Jammu, India
Rajiv Kumar Gupta Department of Community Medicine, Government Medical College, Jammu, India
Rahul Sharma Department of Radiation Oncology, Government Medical College, Jammu, India
Rashmi Kumari Department of Community Medicine, Government Medical College, Jammu, India
Sandeep Kour Department of Radiation Oncology, Government Medical College, Jammu, India
Swarn Singh Katoch Department of Radiation Oncology, Government Medical College, Jammu, India
Rajeev Gupta Department of Medical Oncology, State Cancer Institute, Jammu, India
Aproo Sharma HBCR Project, Government Medical College, Jammu, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20260305

Keywords:

Breast cancer, Clinico epidemiological profile, Trends

Abstract

Background: Breast cancer remains one of the leading causes of malignancy related deaths in women. Understanding the burden of disease and its epidemiology including risk factors are fundamental to public health preventive measures. The study explored the clinic-epidemiological profile and trends of breast cancer in Jammu province of UT of J&K, India.

Methods: Hospital Based Cancer Registry (HBCR) has been in operation since 2014 in Government Medical College Jammu. The data from 2014-2024 was collected as per socio demographic variables, district wise residence and detailed information about clinical profile of the patients. The data was represented as frequency and proportions while trends were reflected using line diagram.

Results: Almost one-third of the patients (30.3%) were in the 45-54 years age group. Similar proportion of the patients was found to be in premenopausal age group. 91% of the patients were married and 63.11% of the total were illiterate. District wise distribution of the patients revealed that almost half (51.60%) of the total belonged to Jammu district. Majority (94.8%) has infiltrating ductal carcinoma on histopathology. At the time of presentation 41.36% were in Stage-II of the disease.

Conclusion: The trends of breast cancer reveal that disease has a steady path with peaks in 2018 and 2019. One third of patients in pre-menopausal age group is a cause of concern. Authors recommend continuous health education regarding warning signals of breast cancer and it’s early screening so that these patients can be diagnosed and treated at an earlier stage.

Metrics

Metrics Loading ...

References

Liu Y, Zheng Z. Understanding the global cancer statistics 2022: growing cancer burden. Science China. Life Sci. 2024;67(10):2274-6. DOI: https://doi.org/10.1007/s11427-024-2657-y

Giaquinto AN, Sung H, Miller KD, Kramer JL, Newman LA, Minihan A, et al. Breast cancer statistics. Cancer J Clin. 2022;72(6):524-41. DOI: https://doi.org/10.3322/caac.21754

Loibl S, Poortmans P, Morrow M, Denkert C, Curigliano G. Epidemiology and risk factors. Breast Cancer. Lancet. 2021;397:1750-69. DOI: https://doi.org/10.1016/S0140-6736(20)32381-3

Hickey M, Basu P, Sassarini J, Stegmann ME, Weiderpass E, Chilowa KN, et al. Managing menopause after cancer. Lancet. 2024;403(10430):984-96. DOI: https://doi.org/10.1016/S0140-6736(23)02802-7

Hu C, Hart SN, Gnanaolivu R, Huang H, Lee KY, Na J, et al. A population-based study of genes previously implicated in breast cancer. New England J Med. 2021;4;384(5):440-51.

Conner SJ, Borges HB, Guarin JR, Gerton TJ, Yui A, Salhany KJ, et al. Obesity induces temporally regulated alterations in the extracellular matrix that drive breast tumor invasion and metastasis. Cancer Res. 2024;84(17):2761-75. DOI: https://doi.org/10.1158/0008-5472.CAN-23-2526

Coughlin SS, Thompson TD, Hall HI, Logan P, Uhler RJ. Breast and cervical carcinoma screening practices among women in rural and nonrural areas of the United States, 1998–1999. Cancer: Interdisciplinary Int J Am Can Soc. 2002;94(11):2801-12. DOI: https://doi.org/10.1002/cncr.10577

Thomas S, Suhani, Desai G, Pathania OP, Jain M, Aggarwal L, et al. Clinico-epidemiological profile of breast cancer patients and the retrospective application of Gail model 2: an Indian perspective. Breast Dis. 2016;36(1):15-22. DOI: https://doi.org/10.3233/BD-150203

Agrawal KH, Rajderkar SS. Clinico-epidemiological profile of female breast cancers and its important correlates: a hospital based study. Natl J Comm Med. 2012;3:316.

Saxena S, Rekhi B, Bansal A, Bagga A, Chintamani, Murthy NS. Clinico-morphological patterns of breast cancer including family history in a New Delhi hospital, India-A cross-sectional study. World J Surg Oncol. 2005;3(1):67. DOI: https://doi.org/10.1186/1477-7819-3-67

Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB. Lyon-France. IARC Scientific Publications. 2002.

Devita VT, Hellman S, Rosenberg SA. Cancer of the breast, in: Cancer Principles and Practice of Oncology, 6th ed. Lippincott Williams and Wilkins. 2001.

Raina V, Bhutani M, Bedi R, Sharma A, Deo SV, Shukla NK, et al. Clinical features and prognostic factors of early breast cancer at a major cancer center in North India, Indian J Cancer. 2005;4:42-5. DOI: https://doi.org/10.4103/0019-509X.15099

Winer EP. Cancer of the breast. In: Vincent De Vita, editor. Cancer principles and Practice of oncology. 6th ed. Philadelphia: Lippincott. 2005: 1651-56.

Laishram RS, Jongkey G, Laishram S, Sharma LD. Clinico-Morphological Patterns of Breast Cancer in Manipur, India. Int J Pathol. 2018;25:40-3.

Naeem M, Khan N, Aman Z, Nasir A, Samad A, Khattak A. Pattern of breast cancer: experience at Lady Reading Hospital, Peshawar. J Ayub Med Coll Abbottabad. 2008;20(4):22-5.