An overview on some important factors affecting male fertility
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20254462Keywords:
Male infertility, Lifestyle factors, Alcohol, Tobacco, Smoking occupational hazards, Environmental factorsAbstract
Infertility is a disease of the reproductive system. It makes a person unable to have children. It can affect both man and women. Any dysfunction in the reproductive system may lead to infertility. Infertility in males is observed as one of the major problem faced by several advanced countries. Over the past several years, a decline in male reproductive health has been reported. Globally, it has been noticed that the incidences of testicular cancer (TC) and poor sperm quality is increasing with time. Certain drugs, lifestyle, tobacco, smoking and alcohol all have a short and long term health effects, including effects detrimental to the production and quality of sperms. In his review we have tried to through some light on the important factors such as lifestyle factors and environmental factors, that can greatly influence over all health wellbeing including fertility.
Metrics
References
Mascarenhas MN, Flaxman SR, Boerma T, Vanderpoel S, Stevens GA. National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Med. 2012;9(12):e1001356. DOI: https://doi.org/10.1371/journal.pmed.1001356
World Health Organization. ICD-11: International Classification of Diseases 11th Revision. Geneva: WHO; 2018.
Gaur DS, Talekar MS, Pathak VP. Alcohol intake and cigarette smoking: impact of two major lifestyle factors on male fertility. Indian J Pathol Microbiol. 2010;53(1):35-40. DOI: https://doi.org/10.4103/0377-4929.59180
Brugo-Olmedo S, Chillik C, Kopelman S. Definition and causes of infertility. Reprod Biomed Online. 2001;2(1):41-53. DOI: https://doi.org/10.1016/S1472-6483(10)62187-6
Firns S, Cruzat VF, Keane KN, Joesbury KA, Lee AH, Newsholme P, et al. The effect of cigarette smoking, alcohol consumption and fruit and vegetable consumption on IVF outcomes: a review and presentation of original data. Reprod Biol Endocrinol. 2015;13(1):134. DOI: https://doi.org/10.1186/s12958-015-0133-x
Condorelli RA, Calogero AE, Vicari E, La Vignera S. Chronic consumption of alcohol and sperm parameters: our experience and the main evidences. Andrologia. 2015;47(4):368–79. DOI: https://doi.org/10.1111/and.12284
La Vignera S, Condorelli RA, Balercia G, Vicari E, Calogero AE. Does alcohol have any effect on male reproductive function? A review of literature. Asian J Androl. 2013;15(2):221-5. DOI: https://doi.org/10.1038/aja.2012.118
Li Y, Lin H, Li Y, Cao J. Association between socio-psycho-behavioral factors and male semen quality: systematic review and meta-analyses. Fertil Steril. 2011;95(1):116–23. DOI: https://doi.org/10.1016/j.fertnstert.2010.06.031
Muthusami KR, Chinnaswamy P. Effect of chronic alcoholism on male fertility hormones and semen quality. Fertil Steril. 2005;84(4):919–24. DOI: https://doi.org/10.1016/j.fertnstert.2005.04.025
Olayaki LA, Edeoja EO, Jimoh OR, Ghazal OK, Olawepo A, Jimoh AG, et al. Effects of cigarette smoking on urinary testosterone excretion in men. Biokemistri. 2008;20(1):29-32. DOI: https://doi.org/10.4314/biokem.v20i1.56435
Colagar AH, Jorsaraee GA, Marzony ET. Cigarette smoking and the risk of male infertility. Pak J Biol Sci. 2007;10(21):3870–4. DOI: https://doi.org/10.3923/pjbs.2007.3870.3874
Durairajanayagam D. Lifestyle causes of male infertility. Arab J Urol. 2018;16(1):10–20. DOI: https://doi.org/10.1016/j.aju.2017.12.004
Asare-Anane H, Bannison SB, Ofori EK, Ateko RO, Bawah AT, Amanquah SD, et al. Tobacco smoking is associated with decreased semen quality. Reprod Health. 2016;13(1):90. DOI: https://doi.org/10.1186/s12978-016-0207-z
Dai JB, Wang ZX, Qiao ZD. The hazardous effects of tobacco smoking on male fertility. Asian J Androl. 2015;17(6):954-60. DOI: https://doi.org/10.4103/1008-682X.150847
Beal MA, Yauk CL, Marchetti F. From sperm to offspring: assessing the heritable genetic consequences of paternal smoking and potential public health impacts. Mutat Res Rev Mutat Res. 2017;773:26–50. DOI: https://doi.org/10.1016/j.mrrev.2017.04.001
Fronczak CM, Kim ED, Barqawi AB. The insults of illicit drug use on male fertility. J Androl. 2012;33(4):515–28. DOI: https://doi.org/10.2164/jandrol.110.011874
Battista N, Pasquariello N, Di Tommaso M, Maccarrone M. Interplay between endocannabinoids, steroids and cytokines in the control of human reproduction. J Neuroendocrinol. 2008;20:82–9. DOI: https://doi.org/10.1111/j.1365-2826.2008.01684.x
Gundersen TD, Jørgensen N, Andersson AM, Bang AK, Nordkap L, Skakkebæk NE, et al. Association between use of marijuana and male reproductive hormones and semen quality. Am J Epidemiol. 2015;182(6):473–81. DOI: https://doi.org/10.1093/aje/kwv135
Bracken MB, Eskenazi B, Sachse K, McSharry JE, Hellenbrand K, Leo-Summers L. Association of cocaine use with sperm concentration, motility, and morphology. Fertil Steril. 1990;53(2):315–22. DOI: https://doi.org/10.1016/S0015-0282(16)53288-9
De Souza GL, Hallak J. Anabolic steroids and male infertility: a comprehensive review. BJU Int. 2011;108(11):1860–5. DOI: https://doi.org/10.1111/j.1464-410X.2011.10131.x
Catalano PM. Management of obesity in pregnancy. Obstet Gynecol. 2007;109(2):419–33. DOI: https://doi.org/10.1097/01.AOG.0000253311.44696.85
Jensen TK, Andersson AM, Jørgensen N, Andersen AG, Carlsen E, Petersen JH, et al. Body mass index in relation to semen quality and reproductive hormones among Danish men. Fertil Steril. 2004;82(4):863–70. DOI: https://doi.org/10.1016/j.fertnstert.2004.03.056
Campbell JM, Lane M, Owens JA, Bakos HW. Paternal obesity negatively affects male fertility and assisted reproduction outcomes: a systematic review and meta-analysis. Reprod Biomed Online. 2015;31(5):593–604. DOI: https://doi.org/10.1016/j.rbmo.2015.07.012
Hammoud AO, Wilde N, Gibson M, Parks A, Carrell DT, Meikle AW. Male obesity and alteration in sperm parameters. Fertil Steril. 2008;90(6):2222–5. DOI: https://doi.org/10.1016/j.fertnstert.2007.10.011
Martini AC, Tissera A, Estofán D, Molina RI, Mangeaud A, de Cuneo MF et al. Overweight and seminal quality: a study of 794 patients. Fertil Steril. 2010;94(5):1739–43. DOI: https://doi.org/10.1016/j.fertnstert.2009.11.017
Chavarro JE, Toth TL, Wright DL, Meeker JD, Hauser R. Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels. Fertil Steril. 2010;93(7):2222–31. DOI: https://doi.org/10.1016/j.fertnstert.2009.01.100
Corona G, Mannucci E, Schulman C, Petrone L, Mansani R, Cilotti A, et al. Psychobiologic correlates of the metabolic syndrome and associated sexual dysfunction. Eur Urol. 2006;50(3):595–604. DOI: https://doi.org/10.1016/j.eururo.2006.02.053
Anderson K, Nisenblat V, Norman R. Lifestyle factors in people seeking infertility treatment – a review. Aust N Z J Obstet Gynaecol. 2010;50(1):8–20. DOI: https://doi.org/10.1111/j.1479-828X.2009.01119.x
Gollenberg AL, Liu F, Brazil C, Drobnis EZ, Guzick D, Overstreet JW, et al. Semen quality in fertile men in relation to psychosocial stress. Fertil Steril. 2010;93(4):1104–11. DOI: https://doi.org/10.1016/j.fertnstert.2008.12.018
Stewart AF, Kim ED. Fertility concerns for the aging male. Urology. 2011;78(3):496–9. DOI: https://doi.org/10.1016/j.urology.2011.06.010
Kimberly L, Case A. Advanced reproductive age and fertility. Int J Gynaecol Obstet. 2012;117(1):95–102. DOI: https://doi.org/10.1016/j.ijgo.2011.11.002
Mutsaerts MAQ, Groen H, Huiting HG, Kuchenbecker WKH, Sauer PJJ, Land JA, et al. Influence of maternal and paternal factors on time to pregnancy. Hum Reprod. 2012;27(2):583–93. DOI: https://doi.org/10.1093/humrep/der429
Eskenazi B, Wyrobek AJ, Sloter E, Kidd SA, Moore L, Young S, et al. The association of age and semen quality in healthy men. Hum Reprod. 2003;18(2):447–54. DOI: https://doi.org/10.1093/humrep/deg107
Gunes S, Hekim GNT, Arslan MA, Asci R. Effects of aging on the male reproductive system. J Assist Reprod Genet. 2016;33(4):441–54. DOI: https://doi.org/10.1007/s10815-016-0663-y
Wu Y, Kang X, Zheng H, Liu H, Liu J. Effect of paternal age on reproductive outcomes of IVF. PLoS One. 2015;10(9):e0135734. DOI: https://doi.org/10.1371/journal.pone.0135734
Mendiola J, Torres-Cantero AM, Vioque J, Moreno-Grau JM, Ten J, Roca M, et al. A low intake of antioxidant nutrients is associated with poor semen quality. Fertil Steril. 2010;93(4):1128–33. DOI: https://doi.org/10.1016/j.fertnstert.2008.10.075
Salas-Huetos A, Bulló M, Salas-Salvadó J. Dietary patterns, foods and nutrients in male fertility parameters. Hum Reprod Update. 2017;23(4):371–89. DOI: https://doi.org/10.1093/humupd/dmx006
Lacasaña M, Vazquez-Grameix H, Borja-Aburto VH, Blanco-Muñoz J, Romieu I, Aguilar‐Garduño C, et al. Maternal and paternal occupational exposure to agricultural work and anencephaly risk. Occup Environ Med. 2006;63(10):649–56. DOI: https://doi.org/10.1136/oem.2005.023333
Jurewicz J, Hanke W, Radwan M, Bonde J. Environmental factors and semen quality. Int J Occup Med Environ Health. 2009;22(4):305–29. DOI: https://doi.org/10.2478/v10001-009-0036-1
Figà-Talamanca I, Traina ME, Urbani E. Occupational exposures to metals, solvents and pesticides: evidence on male reproductive effects. Occup Med (Lond). 2001;51(3):174–88. DOI: https://doi.org/10.1093/occmed/51.3.174
Tielemans E, Van Kooij R, Te Velde ER, Burdorf A, Heederik D. Pesticide exposure and decreased fertilisation rates in vitro. Lancet. 1999;354(9177):484–5. DOI: https://doi.org/10.1016/S0140-6736(99)00599-1
Sidorkiewicz I, Zaręba K, Wołczyński S, Czerniecki J. Endocrine-disrupting chemicals: mechanisms of action on male reproductive system. Toxicol Ind Health. 2017;33(7):601–9. DOI: https://doi.org/10.1177/0748233717695160
Arbuckle TE, Sever LE. Pesticide exposures and fetal death: review of epidemiologic literature. Crit Rev Toxicol. 1998;28(3):229–70. DOI: https://doi.org/10.1080/10408449891344218
Bian Q, Xu LC, Wang SL, Xia YK, Tan LF, Chen JF, et al. Occupational fenvalerate exposure and sperm DNA damage in pesticide workers. Occup Environ Med. 2004;61(12):999–1005. DOI: https://doi.org/10.1136/oem.2004.014597
Rehman S, Usman Z, Rehman S, Aldraihem M, Rehman N, Rehman I, et al. Endocrine disrupting chemicals and impact on male reproductive health. Transl Androl Urol. 2018;7(3):490-503. DOI: https://doi.org/10.21037/tau.2018.05.17
Thonneau P, Bujan L, Multigner L, Mieusset R. Occupational heat exposure and male fertility. Hum Reprod. 1998;13(8):2122–5. DOI: https://doi.org/10.1093/humrep/13.8.2122
Durairajanayagam D, Sharma RK, du Plessis SS, Agarwal A. Testicular heat stress and sperm quality. In: Male Infertility. 2014:105–25. DOI: https://doi.org/10.1007/978-1-4939-1040-3_8
Viganò P, Chiaffarino F, Bonzi V, Salonia A, Ricci E, Papaleo E, et al. Sleep disturbances and semen quality: an Italian study. Basic Clin Androl. 2017;27(1):16. DOI: https://doi.org/10.1186/s12610-017-0060-0
Sharma R, Biedenharn KR, Fedor JM, Agarwal A. Lifestyle factors and reproductive health. Reprod Biol Endocrinol. 2013;11(1):66. DOI: https://doi.org/10.1186/1477-7827-11-66
Meirow D, Biederman H, Anderson RA, Wallace WHB. Toxicity of chemotherapy and radiation on female reproduction. Clin Obstet Gynecol. 2010;53(4):727–39. DOI: https://doi.org/10.1097/GRF.0b013e3181f96b54
Agarwal A, Deepinder F, Sharma RK, Ranga G, Li J. Effect of cell phone usage on semen analysis. Fertil Steril. 2008;89(1):124–8. DOI: https://doi.org/10.1016/j.fertnstert.2007.01.166
Agarwal A, Desai NR, Makker K, Varghese A, Mouradi R, Sabanegh E, et al. Effects of RF-EMW from cellular phones on ejaculated semen: in vitro pilot study. Fertil Steril. 2009;92(4):1318–25. DOI: https://doi.org/10.1016/j.fertnstert.2008.08.022
Adams JA, Galloway TS, Mondal D, Esteves SC, Mathews F. Effect of mobile phones on sperm quality: systematic review. Environ Int. 2014;70:106–12. DOI: https://doi.org/10.1016/j.envint.2014.04.015
Kilgallon SJ, Simmons LW. Image content influences men’s semen quality. Biol Lett. 2005;1(3):253–5. DOI: https://doi.org/10.1098/rsbl.2005.0324
Downloads
Published
How to Cite
Issue
Section
