An epidemiological study on association of maternal stress, anxiety and depression with low birth weight in a tertiary care hospital of Kolkata, West Bengal
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20250923Keywords:
Low birth weight, Preterm baby, Small for date baby, Stress, Anxiety, DepressionAbstract
Background: Low birth weight (LBW) is a significant public health problem globally. In India every 3rd newborn is a LBW contributing to about 40% of the global burden. Maternal stress, anxiety and depression have been shown to impact on the progress and outcome of pregnancy, especially those related to LBW. This study was done to find the psychological factors associated with LBW among babies delivered in a tertiary care hospital in Kolkata.
Methods: It was a cross-sectional institution based observational study conducted from November 2016 to October 2018 among 410 postnatal mothers in the postnatal ward of the department of obstetrics and gynaecology, medical college, Kolkata, West Bengal. Data was obtained by interview method along with record analysis (medical and hospital records). Dependent variable was LBW (<2.5 kg). Ethical clearance was obtained from local ethics committee of all India institute of hygiene and public health Kolkata and medical college, Kolkata.
Results: Out of 410 babies, 112 (27.3%) were LBW. Out of 112 LBW babies, 59 (52.7%) were pre-term (<37 weeks); 51 (45.5%) were term (37-42 weeks) and 2 (1.8%) were post-term (>42 weeks). Among the mothers, 22.0% had anxiety, 17.1% had depression and 65.4% had stress during pregnancy.
Conclusions: In this study, association of LBW with anxiety, depression, both anxiety and depression, stress in mothers during pregnancy was not found. However, minimizing stress and having sufficient sleep during pregnancy is recommended.
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References
WHO/NMH/NHD/ Global Nutrition Targets, Low Birth Weight Policy Brief. 2025.
Kim D, Saada A. The social determinants of infant mortality and birth outcomes in western developed nations: Int J Environ Res Public Health. 2013;10(6):2296-335. DOI: https://doi.org/10.3390/ijerph10062296
Muglia LJ, Katz M. The enigma of spontaneous preterm birth. N Engl J Med. 2010;362(6):529-35. DOI: https://doi.org/10.1056/NEJMra0904308
World Health Organization, March of Dimes, The Partnership for Maternal, New-born and Child Health, Save the Children. Born too soon: the global action report on preterm birth. Geneva. 2012.
World Health Organization, International statistical classification of diseases and related health problems, tenth revision, 2nd ed. 2004.
Dutta DC. Textbook of Obstetrics. 9th edition. Edited by Konar H. New Delhi, India: M/s Jaypee Brothers Medical Publishers (P) Ltd. 2021;427.
Lawn JE, Cousens S, Zupan J. Lancet Neonatal Survival Steering Team. 4 million neonatal deaths: When? Where? Why? Lancet. 2005;365(9462):891-900. DOI: https://doi.org/10.1016/S0140-6736(05)71048-5
Alexander GR, Wingate MS, Bader D, Kogan MD. The increasing racial disparity in infant mortality rates: Composition and contributors to recent US trends. Am J Obstet Gynecol. 2008;198(1):51. e1-9. DOI: https://doi.org/10.1016/j.ajog.2007.06.006
Berkowitz GS, Papiernik E. Epidemiology of preterm birth. Epidemiol Rev. 1993;15(2):414-3. DOI: https://doi.org/10.1093/oxfordjournals.epirev.a036128
Suryakantha AH. Community Medicine with Recent Advances. 4th edition. New Delhi, India: M/s Jaypee Brothers Medical Publishers (P) Ltd. 2017;613.
Suryakantha AH. Community Medicine with Recent Advances. 4th edition. New Delhi, India: M/s Jaypee Brothers Medical Publishers (P) Ltd. 2017;613.
Kliegman RM, Stanton BMD, Geme JS, Schor NF, Behrman RE. Nelson textbook of Paediatrics, Volume-I, 19th edition. Elseiver Philadelphia USA. 2020;555.
Kroenke K, Spitzer RL, Williams JBW, Löwe B. An ultra-brief screening scale for anxiety and depression: the PHQ-4, Psychosomatics. 2009;50(6):613-21. DOI: https://doi.org/10.1016/S0033-3182(09)70864-3
Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress: the PSS-4. J Health Social Behaviour. 1983;24(4):385-96. DOI: https://doi.org/10.2307/2136404
Keenan K, Sheffield R, Boeldt D. Are prenatal psychological or physical stressors associated with suboptimal outcomes in neonates born to adolescent mothers? Early Hum Dev. 2007;83(9):623-7. DOI: https://doi.org/10.1016/j.earlhumdev.2007.01.002
Nasreen HE, Kabir ZN, Forsell Y, Edhborg M. Low birth weight in offspring of women with depressive and anxiety symptoms during pregnancy: results from a population based study in Bangladesh. BMC Public Health. 2010;10:515. DOI: https://doi.org/10.1186/1471-2458-10-515
Bhue PK, Acharya HP, Pradhan SK, Biswal P, Swain AP, Satapathy DM. Sociodemographic factors associated with low birth weight in a tertiary care hospital of Odisha. Int J Community Med Public Health. 2018;5(5):1797-802. DOI: https://doi.org/10.18203/2394-6040.ijcmph20181493
Patale PJ, Masare MS, Bansode Gokhe SS. A study of epidemiological co-relates of low birth weight babies born in tertiary care hospital. Int J Res Med Sci. 2018;6(3):1006-10. DOI: https://doi.org/10.18203/2320-6012.ijrms20180631