Determinants of uptake of pentavalent vaccine in Benin city, Southern Nigeria
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20163935Keywords:
Attitude, Benin city, Determinants, Knowledge, PentavalentAbstract
Background: The Nigerian government in 2012 introduced the pentavalent vaccine into her routine immunization schedule with a view to fast track reduction in child mortality. Despite the advantages of pentavalent vaccine, it has been linked to adverse effects following immunizations including clusters of infant deaths. The objective of the study was to assess knowledge, attitude and experience of care-givers whose under-fives are receiving pentavalent vaccines as determinants of uptake of the vaccine in Benin city.
Methods: A descriptive cross-sectional study design was utilized for this study. Data was analyzed using IBM SPSS version 21.0 software. The level of significance was set at p<0.05. A total of 720 care-givers with mean age (SD) of 29.02±4.8 years participated in this study.
Results: The About three-quarters 554 (76.9%) of caregivers had a good knowledge on pentavalent vaccines. Good knowledge increased with increasing level of education and being married (p≤0.001 and p=0.015 respectively). Majority, 568 (78.9%), of caregivers had a positive attitude towards the pentavalent vaccination. With increasing level of education, there was an increase in the proportion of caregivers who had a positive attitude towards the vaccine (p≤0.001).
Conclusions: Two hundred (27.8%) caregivers had children who had experienced at least a side effect following pentavalent vaccination. Of these, 171 (85.5%) were willing to continue with the vaccine despite AEFIs experienced.
Metrics
References
Wonodi CB, Privor-Dumm L, Aina M, Pate AM, Reis R, Gadhoke P Levine OS. Using social network analysis to examine the decision-making process on new vaccine introduction in Nigeria. Health Policy Plan. 2012;27(suppl 2):ii27-ii38.
World Health Organization. Nigeria launches Penta vaccine. WHO Regional office for Africa, Brazzaville. 2012. Available from http://www.afro.who.int/ en/nigeria/press-materials/ item/4735-nigeria-launches-penta-vaccine.html. Accessed 26/3/2014.
Federal Ministry of Health. National Immunization Policy. National Primary Health Care Development Agency. NPHCDA, 2009; 7-9.
WHO, UNICEF, World Bank. State of the world’s vaccines and immunization, 3rd ed. Geneva, World Health Organization, 2009. Accessed 26/3/2014.
Global Alliance for Vaccines and Immunizations. Pentavalent vaccine support. GAVI. 2014. Available from http://www.gavialliance.org/ support/ nvs/pentavalent/ Accessed 26/3/2014.
Antai D. Inequitable childhood immunization uptake in Nigeria : a multilevel analysis of individual and contextual determinants. BMC Inf dis. 2009;10:1-10
Black RE, Morris SS, Bryce J. Where and why are 10 million children dying every year? Lancet. 2003;361:2226-34
Curry DR. Nigeria introduces pentavalent vaccine. In Vaccines: The Week in Review. Center for Vaccine Ethics & Policy (CVEP). Vaccine . 2012; 30(29):4299-406.
Abdulraheem IS, Onajole AT, Jimoh AAG, Oladipo AR. Reasons for incomplete vaccination and factors for missed opportunities among rural Nigerian children. J Public Health and Epidemiology. 2011;3:194-203.
National Population Commission and ICF Marco. Nigeria Demographic and Health Survey. NpopC/ICF Marco, Abuja. 2009;1-129.
Jheeta M, Newell J. Childhood vaccination in Africa and Asia: the effects of parents’ knowledge and attitudes. Bull World Health Organization. 2008;86(6):419-20.
Suresh KP, Chandrashekara S. Sample size estimation and power analysis for clinical research studies. J Hum Reprod Sci. 2012;5:7-13.
Okpere EE. Clinical obstetrics. Revised edition, University of Benin press, Benin City, Nigeria. 2004;394-95.
Selvaraj K, Sarkar S, Daya PA. Knowledge on routine pentavalent vaccines and socioeconomic correlates among mothers of children aged younger than 5 years in Urban Puducherry. Int J Med Sci Public Health. 2015;4(2):199-204.
Sanaa M. Ahmed, Tarek A. Abd-El Rahman and Eman S. Masoed. Mothers' awareness and knowledge of under five years children regarding immunization in Minia city Egypt. Life Sci J. 2013; 10(4):1224-32.
Adebiyi F, Ibisomi L, Odimegwu CO. Determinants of full child immunization among 12-23 months old in Nigeria. 2013. Presented in International Union for the Scientific Study of Population. Session 039: Poster session on Health, mortality and longevity.
Bernsen RM, Al-Zahmi FR, Al-Ali NA, Hamoudi RO, Ali NA, John Schneider J, et al. Knowledge, Attitude and Practice towards Immunizations among Mothers in a Traditional City in the United Arab Emirates J Med Sci. 2011;4(3):114-21.
Al-Zahrani J. Knowledge, attitude and practice of parents towards childhood vaccination. Majmaah J Health sciences. 2013;1(1):29-38.
Onyiriuka AN. Vaccination default rates among children attending a static immunization clinic in Benin City, Nigeria. J Med Biomedical Res. 2005;4(1):71-7.
Yousif MA, Albarraq AA, Abdallah MAA, Elbur AI (2013) Parents′Knowledge and Attitudes on Childhood Immunization, Taif, Saudi Arabia. J Vaccines Vaccin 5: 215. doi: 10.4172/2157-7560.1000215.
Bar-On ES, Goldberg E, Fraser A, Vidal L, Hellmann S, Leibovici L. Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenzae B (HIB). Cochrane Database Syst Rev. 2009;(3):CD005530.
Merchant N, Waldrop J. The safety advantages of pentavalent vaccines. Am J Pri Health Care. 2012;34(4):48-53.
Dutta AK, Verghese VP, Pemde HK, Mathew LG, Ortiz E. Immunogenicity and Safety of a Pentavalent Diphtheria, Tetanus, Acellular Pertussis, Inactivated Poliovirus, Haemophilus influenzae Type b Conjugate Combination Vaccine (Pentaxim™) with Hepatitis B Vaccine. Indian Pediatrics. 2002;46:975-82.
Taylor LE, Swerdfeger AL, Eslick GD. Vaccines are not associated with autism: An evidence-based meta-analysis of case-control and cohort studies. Vaccine. 2014;32(29):3623-9.
Bonhoeffer J, Heininger U. Adverse Events Following Immunization: perception and evidence. Curr Opin Inf Dis. 2007;20(3):237-46.
Jensen B, Hoang D. Six strategies for solving America’s vaccine dilemma. John Hopkins Public Health. 2015;2;40-5.