Factors associated with lack of viral suppression in human immunodeficiency virus-infected male patients treated with anti-retroviral therapy at Bach Mai hospital, Hanoi
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20250299Keywords:
HIV infection, Vietnam, CD4 T cell counts, Opportunistic infection, Tuberculosis, Lack of viral suppressionAbstract
Background: Viral suppression following anti-retroviral therapy (ART) is one of the most effective factors determining human immunodeficiency virus (HIV) treatment success. However, certain numbers of HIV-infected patients do not experience viral suppression despite ART initiation, which ultimately might lead to treatment failure.
Method: A cross-sectional study was conducted including 194 male patients enrolled at the out-patient clinic, centre for tropical diseases, Bach Mai hospital, Vietnam. Data was analyzed using Stata 12.0.20 for Man-Whitney, Chi-square test/ Fisher’s exact test, and multivariable logistic regression with statistically significant p<0.05.
Results: The results show that being men who have sex with men (aOR=12.14, 95% CI: 1.48-99.49), having low CD4 T cell counts (aOR=269.58, 95% CI: 4.94-14721.27), living in rural areas (aOR=4.63, 95% CI: 1.04-20.57), and not having preventive tuberculosis treatment (aOR=9.92, 95% CI: 1.17-84.10), have increased odds of having detectable viral loads (VL). On the contrary, opportunistic infection was negatively associated with a lack of viral suppression (aOR=0.21, 95% CI: 0.05-0.96).
Conclusions: The results suggest that intervention programs should focus on patients living in rural areas, having low CD4 T cell counts, acquiring opportunistic infection, and MSM patients.
Metrics
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