A study of clinical validation of Unani Pharmacopoeial formulation Habb-e-Hilteet in Zu‘f al-Ishtihā’ (anorexia)"at RRIUM, New Delhi: an open prospective clinical trial

Authors

  • Mohd Talib Husain Regional Research Institute of Unani Medicine, Under CCRUM- New Delhi, Ministry of AYUSH, Govt. of India, India
  • Safder Husain Regional Research Institute of Unani Medicine, Under CCRUM- New Delhi, Ministry of AYUSH, Govt. of India, India https://orcid.org/0000-0003-0149-1510
  • Salma Sultana Regional Research Institute of Unani Medicine, Under CCRUM- New Delhi, Ministry of AYUSH, Govt. of India, India
  • Noman Khan Regional Research Institute of Unani Medicine, Under CCRUM- New Delhi, Ministry of AYUSH, Govt. of India, India
  • Zaki Ahmed Siddiqui Regional Research Institute of Unani Medicine, Under CCRUM- New Delhi, Ministry of AYUSH, Govt. of India, India
  • Ziaul Haq Siddiqui Regional Research Institute of Unani Medicine, Under CCRUM- New Delhi, Ministry of AYUSH, Govt. of India, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20250305

Keywords:

Anorexia, CCRUM, Habb-e-Hilteet, Unani pharmacopoeal formulation

Abstract

Background: Anorexia is a serious condition, especially in older adults, often leading to malnutrition, weight loss, and other severe health problems.  Habb-e-Hilteet is a commonly prescribed Unani pharmacopoeial formulation for anorexia. However, no scientific data are available regarding its safety and efficacy. This study assessed the appetite-inducing effect and safety of Habb-e-Hilteet in Zu‘f al-Ishtihā’ (anorexia) patients.

Methods: An open prospective clinical trial was conducted in 82 clinically diagnosed anorexia patients of either gender (19-65 yrs old). The study was approved by the institutional ethics committee. Habb-e-Hilteet, one pill (500 mg), was administered orally to patients twice daily for 14 days. The safety of the formulation was assessed using important pathological and biochemical indices and by monitoring adverse events. Efficacy was assessed based on improvement in the Simplified Nutritional Appetite Questionnaire (SNAQ) score.

Results: There were 82 participants enrolled in this study. The mean age of the study population was found to be 31.96±11.66years of male, and 31.67±10.81 years of female with a higher rate (69.5%) of occurrence in women. In relation to the Temperament of the Patients, our study found the most effective results in the categories of Damvi (SANGUINE) in 56% of the patients. Our study found a significant correlation (P < 0.000) between the effects of drugs on clinical parameters.

Conclusions: The findings of the study suggest that Habb-e-Hilteet may be a safe and effective treatment for anorexia.

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Published

2025-01-31

How to Cite

Husain, M. T., Husain, S., Sultana, S., Khan, N., Siddiqui, Z. A., & Siddiqui, Z. H. (2025). A study of clinical validation of Unani Pharmacopoeial formulation Habb-e-Hilteet in Zu‘f al-Ishtihā’ (anorexia)"at RRIUM, New Delhi: an open prospective clinical trial. International Journal Of Community Medicine And Public Health, 12(2), 755–761. https://doi.org/10.18203/2394-6040.ijcmph20250305

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Original Research Articles