Assessment of anemia in cases of acute myocardial infarction in a tertiary care hospital in South India

Paidi Shrivatsam; Preeti K. Yadav; Abhijeeth Reddy Toodi; Musaab Abdalla Elhussein; Purna Chand; Lakshmi Chandana Velaga

doi:10.18203/2394-6040.ijcmph20242554

Authors

Paidi Shrivatsam MBBS Student, Government Medical College Srikakulam, Andhra Pradesh, India
Preeti K. Yadav MBBS Graduate, Cama and Albless Hospital, Mumbai, Maharashtra, India
Abhijeeth Reddy Toodi MBBS Graduate, MediCiti institute of medical sciences, Hyderabad, Telangana, India
Musaab Abdalla Elhussein MBBS Graduate, Shendi University, Sudan
Purna Chand MBBS Graduate, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
Lakshmi Chandana Velaga MBBS Graduate, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20242554

Keywords:

Anemia, Hemoglobin, Risk factors, Screening, MI

Abstract

Background: Anemia is a known risk factor for ischemic heart disease and heart failure. It is also associated with increased mortality in acute myocardial infarction (AMI) patients. The study aimed to determine the anemia status of AMI patients and educate them on anemia and its impact on health.

Methods: This was a cross-sectional study conducted among 150 AMI patients admitted to the ICCU of Government General Hospital Srikakulam, Andhra Pradesh over 3 months. Hemoglobin levels were recorded and patients were classified as non-anemic, mildly, moderately, or severely anemic based on WHO criteria. Patients’ sociodemographic profiles and risk factors were also collected.

Results: Of the 150 patients (mean age 59.6 years), 70% were males. 83% of patients had anemia- 67% mild, 12% moderate, and 4% severe. The 50-65 years age group reported the highest frequency of mild anemia cases (38 out of 54). Absence of anemia was highest among the younger 45-50 years group (3 out of 15). Anemia was higher in females, and patients with a vegetarian diet had comparatively more anemia than those consuming a mixed diet. Additionally, 24% of the cases of anemia were in the 65-75 age group.

Conclusions: A high prevalence of anemia was found among AMI patients. Counselling can help improve health by increasing awareness of anemia management. Screening AMI patients for anemia and therapeutic interventions were recommended.

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References

Mendis S, Thygesen K, Kuulasmaa K, Giampaoli S, Mähönen M, Ngu Blackett K, et al. World Health Organization definition of myocardial infarction: 2008-09 revision. Int J Epidemiol. 2011;40(1):139-46.

Salari N, Morddarvanjoghi F, Abdolmaleki A, Rasoulpoor S, Khaleghi AA, Hezarkhani LA, et al. The global prevalence of myocardial infarction: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2023;23(1):206.

Jayaraj JC, Davatyan K, Subramanian SS, Priya J. Epidemiology of myocardial infarction. Myocard Infarct. 2019;10:9-17.

Cappellini MD, Motta I. Anemia in clinical practice- definition and classification: does hemoglobin change with aging? Semin Hematol. 2015;52(4):261-9.

WHO. Anaemia. Available at: https://www.who.int/news-room/fact-sheets/detail/ANAEMIA. Accessed on 9 January 2024.

Hare GM, Mazer CD. Anemia: perioperative risk and treatment opportunity. Anesthesiology. 2021;135(3):520-30.

Kalra SK, Thilagar B, Khambaty M, Manjarrez E. Post-operative anemia after major surgery: a brief review. Curr Emerg Hosp Med Rep. 2021;9(3):89-95.

Shu DH, Ransom TP, O’Connell CM, Cox JL, Kaiser SM, Gee SA, et al. Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes. Cardiovasc Diabetol. 2006;5:1-9.

Wang X, Qiu M, Qi J, Li J, Wang H, Li Y, et al. Impact of anemia on long-term ischemic events and bleeding events in patients undergoing percutaneous coronary intervention: a system review and meta-analysis. J Thorac Dis. 2015;7(11):2041.

Desai A, Oh D, Rao EM, Sahoo S, Mahajan UV, Labak CM, et al. Impact of anemia on acute ischemic stroke outcomes: a systematic review of the literature. PLoS One. 2023;18(1):e0280025.

Padda J, Khalid K, Hitawala G, Batra N, Pokhriyal S, Mohan A, et al. Acute anemia and myocardial infarction. Cureus. 2021;13(8).

Shechter A, Shiyovich A, Skalsky K, Gilutz H, Plakht Y. Interaction between anemia and renal dysfunction in relation to long-term survival following acute myocardial infarction. Clin Res Cardiol. 2024:1-5.

Scott J, Bidulka P, Taylor DM, Udayaraj U, Caskey FJ, Birnie K, et al. Management and outcomes of myocardial infarction in people with impaired kidney function in England. BMC Nephrol. 2023;24(1):325.

Singh A, Ram S, Singh S, Tripathi P. Prevalence and determinants of anaemia among men in rural India: evidence from a nationally representative survey. PLoS Glob Public Health. 2022;2(12):e0001159.

Salisbury AC, Alexander KP, Reid KJ, Masoudi FA, Rathore SS, Wang TY, et al. Incidence, correlates, and outcomes of acute, hospital-acquired anemia in patients with acute myocardial infarction. Circulat Cardiovasc Qual Outcomes. 2010;3(4):337-46.

Farhan S, Baber U, Mehran R. Anemia and acute coronary syndrome: time for intervention studies. J Am Heart Assoc. 2016;5(11):e004908.

Mamas MA, Kwok CS, Kontopantelis E, Fryer AA, Buchan I, Bachmann MO, et al. Relationship between anemia and mortality outcomes in a national acute coronary syndrome cohort: insights from the UK myocardial ischemia national audit project registry. J Am Heart Assoc. 2016;5(11):e003348.

Colombo MG, Kirchberger I, Amann U, Heier M, Thilo C, Kuch B, et al. Association between admission anemia and long-term mortality in patients with acute myocardial infarction: results from the MONICA/KORA myocardial infarction registry. BMC Cardiovasc Disord. 2018;18:1-9.

Gaskell H, Derry S, Andrew Moore R, McQuay HJ. Prevalence of anaemia in older persons: systematic review. BMC Geriatr. 2008;8:1-8.

Alvarez-Uria G, Naik PK, Midde M, Yalla PS, Pakam R. Prevalence and severity of anaemia stratified by age and gender in rural India. Anemia. 2014;2014(1):176182.

Camaschella C. Iron deficiency. Blood. J Am Soc Hematol. 2019;133(1):30-9.

Thakur A, Peepre K, Pendro B, Dhakar JS, Singh TP, Lalu A. Assessment of anemia in cases of acute myocardial infarction in a tertiary care hospital in central India. Int J Community Med Public Health. 2024;11(6):2339-43.