Effects of the use of contraceptives: a case of women in the Greater Accra and Ashanti regions of Ghana

Sara Agyemang Antwi; Jemima Aggrey Appiah; Abenaa Owusuaa Adu

doi:10.18203/2394-6040.ijcmph20240672

Authors

Sara Agyemang Antwi Department of Pharmaceutical Sciences, Kumasi Technical University, Kumasi, Ashanti region, Ghana
Jemima Aggrey Appiah Department of Pharmaceutical Sciences, Kumasi Technical University, Kumasi, Ashanti region, Ghana
Abenaa Owusuaa Adu Department of Pharmaceutical Sciences, Kumasi Technical University, Kumasi, Ashanti region, Ghana

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20240672

Keywords:

Side-effects, Adverse effects, DVT, Uterine fibroids, Hypertension, Combined oral contraceptives, Oral-progestin only contraceptives

Abstract

Background: Contraceptive use during a woman's reproductive years can help prevent unintended pregnancies, maternal deaths, and other non-reproductive problems. However, there is also a risk of running into various health challenges. The study aimed at finding out if women in the Greater Accra and Ashanti regions of Ghana encounter health issues during and after use of contraceptives was conducted.

Methods: Questionnaires were administered to 600 women out of which 401 responses were carefully gleaned for analysis using SPSS version 25. The questionnaire probed side and adverse effects women encountered in their use of contraceptives as well as the types of contraceptives they preferred.

Results: The study revealed that the use of contraceptives was widely prevalent, especially amongst women aged 21-30 years (61.8%). The preferred types of contraceptives were the oral-progestin only (42.9%) and combined oral contraceptives (31.4%). Spotting or bleeding between periods (menstrual-related) was the highest reported side effect (33.2%), followed by weight gain (metabolic-related), 21.7%. Pearson’s Chi squared test showed an association between the age of respondents and the choice of contraceptive type at p<0.01. Hypertension and deep vein thrombosis (DVT) were the highest reported adverse effect (10.2% and 9.2% respectively).

Conclusions: It was concluded that contraceptive use (especially the oral type) may cause discomfort with the side effects reported in women of reproductive age and it may be a contributing factor to other health conditions in susceptible women.

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References

Higgins JA, Smith NK. The sexual acceptability of contraception: reviewing the literature and building a new concept. J Sex Res. 2016;53(4-5):417-56.

Cameron ST. Contraception and sterilization. Dewhurst’s Textbook of Obstetrics and Gynecology 9th Edition. John Wiley and Sons, Ltd, west Sussex UK. 2018:939-53.

undesa_pd_2022_world-family-planning. Available at: https://www.un.org/development/desa/pd/sites/ www.un.org.development.desa.pd/files/files/documents/2023/Feb/. Accessed on 10 February, 2024.

Kahlenborn C, Peck R, Severs WB. Mechanism of action of levonorgestrel emergency contraception. The Linacre Quarterly. 2015;82(1):18-33.

Endler M, Li RH, Danielsson KG. Effect of levonorgestrel emergency contraception on implantation and fertility: A review. Contraception. 2022;109:8-18.

Edietah EE, Njotang PN, Ajong AB, Essi MJ, Yakum MN, Mbu ER. Contraceptive use and determinants of unmet need for family planning; a cross sectional survey in the North West Region, Cameroon. BMC Women's Heal. 2018;18:1-8.

Arowojolu AO, Okewole IA. Vaginal bleeding following the use of a single dose of 1.5 mg levonorgestrel. Parity. West Afr J Med. 2004;23(3):191-3.

Leelakanok N, Methaneethorn J. A systematic review and meta-analysis of the adverse effects of levonorgestrel emergency oral contraceptive. Clin Drug Investigation. 2020;40:395-420.

Tanis BC, Rosendaal FR. Venous and arterial thrombosis during oral contraceptive use: risks and risk factors. In Seminars in Vascular Medicine. 2003;069-84.

Teye JK. Modern contraceptive use among women in the Asuogyaman district of Ghana: is reliability more important than health concerns? Afri J Reproduct Heal. 2013;17(2):58-71.

Agyepong KO. Attitude, knowledge and usage of contraceptives among men in Ejura Sekyedumase (Doctoral dissertation, University of Cape Coast). Thesis. 2019.

MacGregor EA. Contraception and headache. Headache: J Head Face Pain. 2013;53(2):247-76.

Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Europ J Pain. 2006;10(4):287-333.

Sabatini R, Cagiano R, Rabe T. Adverse effects of hormonal contraception. J Reproduct Med Endocrinol. 2011;8(1):130-56.

Rodriguez MI, Godfrey EM, Warden M, Curtis KM. Prevention and management of nausea and vomiting with emergency contraception: a systematic review. Contraception. 2013;87(5):583-9.

Zhong W, Shahbaz O, Teskey G, Beever A, Kachour N, Venketaraman V, et al. Mechanisms of nausea and vomiting: current knowledge and recent advances in intracellular emetic signaling systems. Int J Molecular Sci. 2021;22(11):5797.

Gallo MF, Lopez LM, Grimes DA, Carayon F, Schulz KF, Helmerhorst FM. Combination contraceptives: effects on weight. Cochrane Database Syst Rev. 2014(1):CD003987.

Edelman A, Jensen JT, Bulechowsky M, Cameron J. Combined oral contraceptives and body weight: do oral contraceptives cause weight gain? A primate models. Human Reproduct. 2011;26(2):330-6.

Hubacher D, Chen PL, Park S. Side effects from the copper IUD: do they decrease over time? Contraception. 2009;79(5):356-62.

Archer DF, A-Philput C, Weber ME. Management of irregular uterine bleeding and spotting associated with Norplant®. Human Reproduct. 1996;11:24-30.

Zimmerman LA, Sarnak DO, Karp C, Wood SN, Yihdego M, Shiferaw S, Seme A. Measuring experiences and concerns surrounding contraceptive induced side-effects in a nationally representative sample of contraceptive users: evidence from PMA Ethiopia. Contraception: X. 2022;4:100074.

Stegeman BH, De Bastos M, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, et al. Different combined oral contraceptives, and the risk of venous thrombosis: systematic review and network meta-analysis. BMJ. 2013;347:f5298.

Sugiura K, Kobayashi T, Ojima T. Thromboembolism as the adverse event of combined oral contraceptives in Japan. Thrombosis Res. 2015;136(6):1110-5.

Van Raalte DH, Diamant M. Steroid diabetes: from mechanism to treatment. Neth J Med. 2014;72(2):62-72.

Pillay D, Morroni C, Pleaner M, Adeagbo OA, Chersich MF, Naidoo N, et al. Gaps in monitoring systems for Implanon NXT services in South Africa: An assessment of 12 facilities in two districts. S Afr Med J. 2017;107(10):827-3.