Emerging bacterial and fungal pathogens in healthcare and the threat of drug resistance

Khaled Swailem Alzahrani; Khulood Majed Almutairi; Afaf Wazin Alsulami; Abdulrhman Mohmmed Aseeri; Mohammed Ahmed Alqarni; Arwa Ahmad Haffah; Muhannad Fahad Alqahtani; Mohammed Fahad Almistadi; Saad Ali Bin Muaddi; Hanin Abdulrahman Ayoub

doi:10.18203/2394-6040.ijcmph20233831

Authors

Khaled Swailem Alzahrani Department of Hematology, King Fahad General Hospital, Jeddah, Saudi Arabia
Khulood Majed Almutairi Department of Hematology, Imam Abdulrahman Al Faisal Hospital, Riyadh, Saudi Arabia
Afaf Wazin Alsulami Department of Hematology, King Fahad General Hospital, Jeddah, Saudi Arabia
Abdulrhman Mohmmed Aseeri Department of Hematology, King Fahad General Hospital, Jeddah, Saudi Arabia
Mohammed Ahmed Alqarni Department of Laboratory, Thurayban General Hospital, Thurayban, Saudi Arabia
Arwa Ahmad Haffah Department of Laboratory, Khamis Mushait Maternity and Children Hospital, Khamis Mushait, Saudi Arabia
Muhannad Fahad Alqahtani Department of Blood Bank, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
Mohammed Fahad Almistadi Department of Blood Bank, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
Saad Ali Bin Muaddi Department of Laboratory, Khamis Mushait Maternity and Children Hospital, Khamis Mushait, Saudi Arabia
Hanin Abdulrahman Ayoub Department of Anatomic Pathology, King Fahad General Hospital, Jeddah, Saudi Arabia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20233831

Keywords:

Antimicrobial stewardship, Drug resistance, Rapid diagnostics, Infection control, Personalized treatment

Abstract

Managing the treatment of fungal infections, in healthcare facilities is extremely important as drug resistance continues to rise. It's crucial to have programs that oversee the use of antibiotics which can help reduce the emergence of resistance. Rapid diagnostic tools like polymerase chain reaction and next generation sequencing (PCR and NGS) are helpful in targeting treatment plans. Implementing rigorous infection control protocols can effectively reduce the transmission of infections, within healthcare facilities. Collaborative efforts between specialists ensure customized treatment plans that address resistance profiles. Combating evolving drug resistance involves approaches such as combination therapy and immunotherapies. Educating healthcare workers and patients about infection prevention and control is essential. Surveillance and epidemiology play a role in tracking resistance patterns, which in turn guide interventions. International cooperation is crucial due to travel patterns. Continuous research and innovation are essential for management providing insights into treatment effectiveness and mechanisms of resistance. The clinical implications of drug resistance such as increased severity, treatment failures and limited options underscore the need, for an approach. In conclusion, it is imperative to have clinical management strategies to tackle the challenges posed by emerging drug pathogens while safeguarding patient outcomes and public health.

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