Determinants of human immuno-deficiency virus pre-exposure prophylaxis uptake and retention among sex workers in Nakuru town Kenya
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20241470Keywords:
HIV pre-exposure prophylaxis, Female commercial sex workers, Uptake and retention, Socio economic individual factors, Awareness, Health system factors, Nakuru townAbstract
Background: The purpose of this study was to assess factors associated with human immunodeficiency virus (HIV) pre-exposure prophylaxis uptake and retention among sex workers in Nakuru town, Kenya. The theory of planned behavior and the acquired immunodeficiency syndrome (AIDS) risk reduction model served as the study's theoretical framework.
Methods: A cross-sectional research design was adopted for this study. The study targeted all the sex workers in Nakuru town who were 18 years old and above. A random sampling technique was used to get the hotspots where the sex workers were to be found. Snow balling sampling technique was then adopted to identify and recruit the study participants. Using primary sources. The quantitative data was obtained from the respondents using a questionnaire. Quantitative data was analyzed using descriptive and inferential statistics (regression analysis). The findings presented in table and graphical formats.
Results: The analysis using multiple linear regression indicated that there was a collective significant effect between the awareness, health system factors, socio economic individual factors and use of pre-exposure prophylaxis (PrEP) among sex workers. A further analysis showed that, put together, the four predictor variables explained 35.7% of variation on PrEP uptake and retention.
Conclusions: The study concluded that while use and none use PrEP can be explained by the four factors evaluated in this study, there are a lot of other factors that influence utilization of PrEP.
References
Anyona, MO. Determinants of Continuation on Pre-exposure Prophylaxis: a Case of Nairobi County, Kenya (Doctoral dissertation, University of Nairobi). 2019.
Muwonge TR, Nsubuga R, Brown C, Nakyanzi A, Bagaya M, Bambia F, et al. Knowledge and barriers of PrEP delivery among diverse groups of potential PrEP users in Central Uganda. PLoS One. 2020;15(10):e0241399.
Kagaayi J, Batte J, Nakawooya H, Kigozi B, Nakigozi G, Strömdahl S, et al. Uptake and retention on HIV pre-exposure prophylaxis among key and priority populations in South-Central Uganda. J Int AIDS Soc. 2020;23(8):e25588.
World Health Organization. WHO Expands Recommendation on Oral Pre-Exposure Prophylaxis of HIV Infection (PrEP). 2018. Available at: https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/hiv/prevention/pre-exposure-prophylaxis. Accessed on 09 March 2024.
World Health Organization. Global data shows increasing PrEP use and widespread adoption of WHO PrEP recommendations. 2021. Available at: https://www.who.int/news‐room/feature‐stories/detail/global‐data‐shows‐increasing‐prep‐use‐and‐widespread‐adoption‐of‐who‐prep‐recommendations. Accessed on 09 March 2024.
Begnel ER, Escudero J, Mugambi M, Mugwanya K, Kinuthia J, Beima-Sofie K, et al. High pre-exposure prophylaxis awareness and willingness to pay for pre-exposure prophylaxis among young adults in Western Kenya: results from a population-based survey. Int J STD AIDS. 2020;31(5):454-9.
Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587-99.
McKinnon LR, Gakii G, Juno JA, Izulla P, Munyao J, Ireri N, et al. High HIV risk in a cohort of male sex workers from Nairobi, Kenya. Sex Transm Infect. 2014;90(3):237-42.
Shannon K, Strathdee SA, Goldenberg SM, Duff P, Mwangi P, Rusakova M, et al. Global epidemiology of HIV among female sex workers: influence of structural determinants. The Lancet. 2015;385(9962):55-71.
Beyrer C, Crago AL, Bekker LG, Butler J, Shannon K, Kerrigan D, et al. An action agenda for HIV and sex workers. Lancet. 2015;385(9964):287-301.
Ministry of Health (MOH). Guidelines on Use of Antiretroviral Drugs for Treating and Preventing HIV Infection in Kenya. 2014. Available at: https://aidsfree.usaid.gov/sites/default/files/tx_kenya_2014.pdf. Accessed on 09 March 2024.
National AIDS and STI Control Programme (NASCOP) & Ministry of health (MOH). 2018. Turning the Tide: Preventing New HIV Infection & Optimizing Treatment Outcomes. 2018 HIV Prevention, Care & Treatment Scientific Conference, Nairobi. Available at: https://www.nascop.or.ke/. Accessed on 09 March 2024.
Kiragu M. PrEP Roll-out in Kenya. Oral presentation at the International AIDS Conference; Durban South Africa. 2016.
Restar AJ, Tocco JU, Mantell JE, Lafort Y, Gichangi P, Masvawure TB, et al. Perspectives on HIV Pre- and Post-Exposure Prophylaxes (PrEP and PEP) Among Female and Male Sex Workers in Mombasa, Kenya: Implications for Integrating Biomedical Prevention into Sexual Health Services. AIDS Educ Prev. 2017;29(2):141-53.
Ng’ethe RMB. Factors associated with uptake of hiv and aids combination prevention strategies among female sex workers in Nakuru County, Kenya (Doctoral dissertation, Kenyatta University). 2020.
Ajzen I. The Theory of Planned Behavior. Organizational Behavior and Human Decision Processes. 1991;50(2):179-211.
Ajzen I, Madden TJ. Prediction of goal-directed behavior: Attitudes, inten-tions, and perceived behavioral control. J Exp Soc Psychol. 1986;22:45:374.
Sussman R. Causality in the Theory of Planned Behavior. Personality and Social Psychology Bulletin. 2019;45(6):920-33.
Croucher SM. Understanding Communication Theory: A Beginner's Guide. Routledge. 2015.
Catania JA, Kegeles SM, Coates TJ. Towards an understanding of risk behavior: an AIDS risk reduction model (ARRM). Health Educ Q. 1990;17(1):53-72.
Ndaga AEA. Socioeconomic Inequality in Hiv Prevention Amongst Female Sex Workers: an Analysis of Pre-exposure Prophylaxis Use (Doctoral dissertation, University of Nairobi). 2020.
Lankowski AJ, Bien-Gund CH, Patel VV, Felsen UR, Silvera R, Blackstock OJ. PrEP in the Real World: Predictors of 6-Month Retention in a Diverse Urban Cohort. AIDS Behav. 2019;23(7):1797-802.
