Effect of supplementation of Purslane-Portulaca oleracea in hypercholesterolemic subjects

S. Tarkergari; K. Waghray; S. Gulla

doi:10.18203/2394-6040.ijcmph20233118

Authors

Tarkergari BHEL General Hospital, Ramachandrapuram, Hyderabad, Telangana, India
K. Waghray School of Food Technology and Nutrition, Loyola Academy, Alwal, Secunderabad, Telangana, India
S. Gulla Department of Food Technology, College of Technology, Osmania University, Hyderabad, Telangana, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20233118

Keywords:

Medicinal, Food adjunct, Hypercholesterolemic, Supplementation, Cholesterol and its fractions

Abstract

Background: Portulaca oleracea (Purslane) is a medicinal plant containing diverse phyto constituents grown all over the world. Several studies have reported its pharmacological effects like, antihypertensive, anti-inflammatory antioxidant, hypoglycemic, hypocholesterolemic, hypotriglyceridemia neuroprotective effects.

Methods: Dried Portulaca oleraca leaves were incorporated into spice powder/ karampodi a south India food adjunct which was used for supplementation studies for 90 days (3 months) among hyper cholesterolemic subjects after obtaining a written informed consent. Biochemical parameters like lipid profile, i.e., total cholesterol, low density lipoprotein cholesterol, triglycerides, high density lipoprotein cholesterol, very low-density lipoprotein cholesterol, kidney function test, Liver function test were assessed. Baseline information, their medical history and 24hr dietary recall was elicited from the subjects through a pretested schedule.

Results: The results have shown that the total cholesterol levels and its fractions along with triglycerides were significantly decreased, HDL-C increased significantly in the test groups from pre- supplementation to during-supplementation and were stable at post-supplementation period.

Conclusions: Our results indicated that the spice powder was rich in polyunsaturated fatty acid had a strong hypo cholesterolemic and hypotriglyceridemic effect.

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