Guardian willingness to vaccinate adolescent daughters against human papillomavirus for cervical cancer prevention in hard-to-reach communities in Mandera County, Kenya

Authors

  • Ifrah S. Mohamed Department of Community Health, Epidemiology and Biostatistics, College of Health Sciences, Mount Kenya University, Nairobi, Kenya
  • Joseph M. Muchiri Department of Community Health, Epidemiology and Biostatistics, College of Health Sciences, Mount Kenya University, Nairobi, Kenya
  • Francis W. Makokha Department of Research and Innovation, Mount Kenya University, Nairobi, Kenya

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20233084

Keywords:

HPV vaccine, Cervical cancer, Hard-to-reach communities

Abstract

Background: Cervical cancer is the fourth most frequent disease in women, and in 2020, there was an estimated 604,127 new cases and 342,831 fatalities worldwide. Despite the fact that cervical cancer can be easily treated if detected early, Sub-Saharan Africa suffers the greatest incidence of cervical cancer morbidity and mortality. The purpose of this study was to ascertain parents' readiness to protect teenage girls from Human Papillomavirus.

Methods: The study used a cross-sectional descriptive strategy conducted among guardians of adolescent girls in rural area in Mandera. A simple random sampling technique was adopted and data was collected through key informant interviews, focus group discussions, and pretested interviewer-administered questionnaires.

Results: The study's findings demonstrated that while parental understanding of the HPV vaccine was low in our study area, parental awareness was high. This resulted in low parental acceptance of the HPV vaccine, which in turn resulted in low uptake. The study participants' degree of vaccination acceptance was low (30%), with the majority showing hesitation (54%). Socio-cultural factors and religion were identified as the main barriers to HPV vaccine acceptance among the participants.

Conclusions: The findings of our study demonstrate that although guardians in the research area had a high level of awareness of the HPV vaccine, there was poor uptake of the vaccine due to low knowledge and sociocultural reasons. Despite the fact that these services were both ample and accessible.

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References

Abdi B, Okal J, Serour G, Temmerman M. "Children are a blessing from God" - a qualitative study exploring the socio-cultural factors influencing contraceptive use in two Muslim communities in Kenya. Reprod Health. 2020;17(1):44.

American Cancer Society. Cancer facts and figures 2020. Atlanta: ACS; 2020.

Amponsah-Dacosta E, Blose N, Nkwinika VV, Chepkurui V. Human Papillomavirus Vaccination in South Africa: Programmatic Challenges and Opportunities for integration with other adolescent health services? Front Public Health. 2022;10:799984.

Asempah E, Mboumba Bouassa RS, Prazuck T, Lethu T, Jenabian MA, Meye JF, Bélec L. Cervical cancer in sub-Saharan Africa: a preventable noncommunicable disease. Expert Rev Anti Infect Ther. 2017;15(6):613-27.

Audu BM, Bukar M, Ibrahim AI, Swende TZ. Awareness and perception of human papilloma virus vaccine among healthcare professionals in Nigeria. J Obstet Gynaecol. 2014;34(8):714-7.

Bolarinwa OA. Principles and methods of validity and reliability testing of questionnaires used in social and health science researches. Niger Postgrad Med J. 2015; 22(4):195-201.

Chiang VC, Wong HT, Yeung PC, Choi YK, Fok MS, Mak OI, Wong HY, Wong KH, Wong SY, Wong YS, Wong EY. Attitude, Acceptability and Knowledge of HPV Vaccination among Local University Students in Hong Kong. Int J Environ Res Public Health. 2016; 13(5):486.

Dereje N, Ashenafi A, Abera A, Melaku E, Yirgashewa K, Yitna M, et al. Knowledge and acceptance of HPV vaccination and its associated factors among parents of daughters in Addis Ababa, Ethiopia: a community-based cross-sectional study. Infect Agent Cancer. 2021;16(1):58.

Shewaye S, Fasil T, Yoseph Y. Eliminating cervical cancer. Lancet. 2020.

Gavi H. Overview of COVID-19 Situation in GAVI-Supported Countries and GAVI’s Response. J Obstet Gynaecol. 2012;32(3):209-13.

Karanja-Chege CM. HPV Vaccination in Kenya: The Challenges Faced and Strategies to Increase Uptake. Front Public Health. 2022;10:802947.

Gliem JA, Gliem RR. Calculating, interpreting, and reporting Cronbach’s alpha reliability coefficient for Likert-type scales. Midwest Research-to-Practice Conference in Adult, Continuing, and Community Education. Front Public Health. 2010;23:30-9.

Hall MT, Simms KT, Lew JB. The projected timeframe until cervical cancer elimination in Australia: a modelling study. Lancet Public Health. 2019;4(1):e19-27.

Li Y, Xu C. Human Papillomavirus-Related Cancers. Adv Exp Med Biol. 2017;1018:23-34.

Ngune I, Kalembo F, Loessl B, Kivuti-Bitok LW. Biopsychosocial risk factors and knowledge of cervical cancer among young women: A case study from Kenya to inform HPV prevention in Sub-Saharan Africa. PLoS One. 2020;15(8):e0237745.

Jedy-Agba E, Joko WY, Liu B, Buziba NG, Borok M, Korir A, et al. Trends in cervical cancer incidence in sub-Saharan Africa. Br J Cancer. 2020;123(1):148-54.

Karanja-Chege CM. HPV Vaccination in Kenya: The Challenges Faced and Strategies to Increase Uptake. Front Public Health. 2022;10:802947.

Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y, Jin T. Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation. Front Public Health. 2021;8:552028.

Lekoane KMB, Kuupiel D, Mashamba-Thompson TP, Ginindza TG. Evidence on the prevalence, incidence, mortality and trends of human papilloma virus-associated cancers in sub-Saharan Africa: systematic scoping review. BMC Cancer. 2019;19(1):563.

Leung SOA, Akinwunmi B, Elias KM, Feldman S. Educating healthcare providers to increase Human Papillomavirus (HPV) vaccination rates: A Qualitative Systematic Review. Vaccine X. 2019;3:100037.

Habila MA, Kimaru LJ, Mantina N, Valencia DY, McClelland DJ, Musa J, et al. Community-Engaged Approaches to Cervical Cancer Prevention and Control in Sub-Saharan Africa: A Scoping Review. Front Glob Womens Health. 2021;2:697607.

Ngune I, Kalembo F, Loessl B, Kivuti-Bitok LW. Biopsychosocial risk factors and knowledge of cervical cancer among young women: A case study from Kenya to inform HPV prevention in Sub-Saharan Africa. PLoS One. 2020 Aug 20;15(8):e0237745.

Oh NL, Biddell CB, Rhodes BE, Brewer NT. Provider communication and HPV vaccine uptake: A meta-analysis and systematic review. Prev Med. 2021; 148:106554.

Okedo-Alex IN, Akamike IC, Ezeanosike OB, Uneke CJ. Determinants of antenatal care utilisation in sub-Saharan Africa: a systematic review. BMJ Open. 2019;9(10):e031890.

Perlman S, Wamai RG, Bain PA, Welty T, Welty E, Ogembo JG. Knowledge and awareness of HPV vaccine and acceptability to vaccinate in sub-Saharan Africa: a systematic review. PLoS One. 2014;9(3): e90912.

Toh ZQ, Russell FM, Garland SM, Mulholland EK, Patton G, Licciardi PV. Human Papillomavirus Vaccination After COVID-19. JNCI Cancer Spectr. 2021; 5(2):11.

Torjesen I. HPV vaccine: high coverage could eradicate cervical cancer within decades, say researchers. Br Med J. 2016;23:365.

Progress and challenges with achieving universal immunization coverage. Available at: https://www.who.int/. Accessed on 20 February 2023.

Venturas C, Umeh K. Health professional feedback on HPV vaccination roll-out in a developing country. Vaccine. 2017;35(15):1886-91.

Vermandere H, Naanyu V, Mabeya H, Vanden Broeck D, Michielsen K, Degomme O. Determinants of acceptance and subsequent uptake of the HPV vaccine in a cohort in Eldoret, Kenya. PLoS One. 2014; 9(10):e109353.

WHO Global strategy to eliminate cervical cancer article. Available at: https://www.who.int/. Accessed on 20 February 2023.

Zhelyazkova A, Kim S, Klein M, Prueckner S, Horster S, Kressirer P, et al. COVID-19 Vaccination Intent, Barriers and Facilitators in Healthcare Workers: Insights from a Cross-Sectional Study on 2500 Employees at LMU University Hospital in Munich, Germany. Vaccines (Basel). 2022;10(8):1231.

Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020;8(2):e191-203.

Becker-Dreps S, Otieno WA, Brewer NT, Agot K, Smith JS. HPV vaccine acceptability among Kenyan women. Vaccine. 2010;28(31):4864-7.

Bolarinwa OA. Principles and methods of validity and reliability testing of questionnaires used in social and health science researches. Niger Postgrad Med J. 2015;22(4):195-201.

Bruni L, Saura-Lázaro A, Montoliu A, Brotons M, Alemany L, Diallo MS, et al. HPV vaccination introduction worldwide and WHO and UNICEF estimates of national HPV immunization coverage 2010-2019. Prev Med. 2021 Mar;144:106399.

Bangura JB, Xiao S, Qiu D, Ouyang F, Chen L. Barriers to childhood immunization in sub-Saharan Africa: A systematic review. BMC Public Health. 2020;20(1):1108.

Hoque ME. Factors influencing the recommendation of the Human Papillomavirus vaccine by South African doctors working in a tertiary hospital. Afr Health Sci. 2016;16(2):567-75.

Hussain AN, Alkhenizan A, McWalter P, Qazi N, Alshmassi A, Farooqi S, Abdulkarim A. Attitudes and perceptions towards HPV vaccination among young women in Saudi Arabia. J Family Community Med. 2016;23(3):145-50.

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Published

2023-09-30

How to Cite

Mohamed, I. S., Muchiri, J. M., & Makokha, F. W. (2023). Guardian willingness to vaccinate adolescent daughters against human papillomavirus for cervical cancer prevention in hard-to-reach communities in Mandera County, Kenya. International Journal Of Community Medicine And Public Health, 10(10), 3550–3555. https://doi.org/10.18203/2394-6040.ijcmph20233084

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Original Research Articles