Study of morphometric changes of cornea in cases of pterygium

Authors

  • Mukesh Kumar Department of Ophthalmology, SP Medical College, Bikaner, Rajasthan, India
  • Shaheen Farooq Department of Ophthalmology, SP Medical College, Bikaner, Rajasthan, India
  • Nabab A. Khan Department of Ophthalmology, SP Medical College, Bikaner, Rajasthan, India
  • Anju Kochar Department of Ophthalmology, SP Medical College, Bikaner, Rajasthan, India
  • Prinyanka Sunda Department of Ophthalmology, SP Medical College, Bikaner, Rajasthan, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20233765

Keywords:

Endothelial cell density, Keratometry, Pterygium

Abstract

Background: Pterygium is a benign, wing-shaped, fibrovascular growth that originates on the bulbar conjunctiva and can spread to the limbus and beyond, causing morphometric changes in the cornea and affecting visual status. Aim of study was to study the morphometric changes in the cornea in patients with pterygium.

Methods: Prospective hospital-based analytical study conducted on 100 consecutive patients with unilateral pterygium for two years. Each patient underwent a complete ophthalmic examination, including evaluation of visual acuity refraction, corneal curvature, corneal endothelial cell density (CECD), central corneal thickness (CCT), coefficient of variation (CV) and hexagonality. Necessary demographic data and variables like age, smoking status and occupation were also determined. The healthy eye was considered as a control.

Results: Majority of the study population, i.e. 43%, belonging to the 21-40 years of age group; socioeconomically, maximum cases (61%) were found in class IV with a male preponderance of 53%. 56% of patients hailed from rural areas, and regarding occupation, it was found that 37% of patients were farmers. This study found that the majority of patients (60% of cases) had multiple ocular complaints. There was a significant association between pterygium grade and keratometric astigmatism. Our study found a significant difference between ECD, hexagonality and CV in the normal and diseased eye. CCT was found more in diseased eyes but was significant only in grade IV pterygium.

Conclusions: Pterygium leads to deterioration of visual performance by causing refractive and keratometric changes.

References

Mackenzie FAD, Hirst LW, Battistutta D, Green A. Risk analysis in the development of pterygia. Opthalmol. 1992;99(7):1056.

Bradley PG, William MT. Pterygium. In: Kaufman (ed). 2nd ed. The Cornea Butterworth-Hienmann Boston; 1998:497-521.

Chui J, Di Girolamo N, Wakefield D, Coroneo MT. The pathogenesis of pterygium: current concepts and their therapeutic implications. Ocul Surf. 2008;6(1):24-43.

Johnston SC, Williams PB, Sheppard JD. A comprehensive system for pterygium classification. Invest Ophthalmol Vis Sci. 2004;45(13):2940.

Han SB, Jeon HS, Kim M, Lee SJ, Yang HK, Hwang JM, et al. Quantification of astigmatism induced by pterygium using automated image analysis. Cornea. 2016;35(3):370-6.

Zaidi SBH, Khan WA. Is pterygium morphology related to loss of corneal endothelial cells? a cross-sectional study. Clin Ophthalmol. 2021;15:1259-66.

Khoo J, Saw SM, Banerjee K, Chia SE, Tan D. Outdoor work and the risk of pterygia: a case-control study. Int Ophthalmol. 1998;22(5):293-8.

Nemesure B, Wu SY, Hennis A, Leske MC, Barbados Eye Studies Group. Nine-year incidence and risk factors for pterygium in the barbados eye studies. Ophthalmology 2008;115(12):2153–8.

Songur MS, Erkan E, Bayhan SA, Bayhan HA. Evaluation of changes in corneal endothelial morphology during the progression of pterygium by specular microscopy. J Surg Med. 2021;5(7):679-82.

Vanathi M, Goel S, Ganger A, Agarwal T, Dada T, Khokhar S. Corneal tomography and biomechanics in primary pterygium. Int Ophthalmol. 2018;38(2):663-71.

Souley AS, Sambou KF, Adam ND, Joanelle EL, Abdou A. Case series about physiological astigmatism and the impact of pterygium surgery. Ann Med Surg (Lond). 2022;81:104488.

Tseng SC. Concept and application of limbal stem cells. Eye. 1989;3(2):141-57.

Sousa HCC, Silva LNP, Tzelikis PF. Corneal endothelial cell density and pterygium: a cross-sectional study. Arq Bras Oftalmol. 2017;80(5):317-20.

Mootha VV, Pingree M, Jaramillo J. Pterygia with deep corneal changes. Cornea. 2004;23(6):635-8.

Hu Y, Atik A, Qi W, Yuan L. The association between primary pterygium and corneal endothelial cell density. Clin Exp Optom. 2020;103:778-81.

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Published

2023-11-30

How to Cite

Kumar, M., Farooq, S., Khan, N. A., Kochar, A., & Sunda, P. (2023). Study of morphometric changes of cornea in cases of pterygium. International Journal Of Community Medicine And Public Health, 10(12), 4694–4698. https://doi.org/10.18203/2394-6040.ijcmph20233765

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Section

Original Research Articles