Rare cause of biliary obstruction from myeloid sarcoma has better prognosis, if timely diagnosed: case report with literature review

Ariyan Khan; Suresh Chandra Annu; Juwairiah Abdur Raheem; Rajasekhar Angajala

doi:10.18203/2394-6040.ijcmph20232058

Authors

Ariyan Khan Intern, Department of Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India
Suresh Chandra Annu Department of Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India
Juwairiah Abdur Raheem Intern, Department of Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India
Rajasekhar Angajala National Pathology Laboratory, Hyderabad, Telangana, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20232058

Keywords:

Extramedullary myeloid sarcoma, Biliary stricture, Obstructive jaundice

Abstract

Extramedullary myeloid sarcoma (EMMS) involving the biliary tract is extremely rare. We describe, a case of a 40-year-old gentleman who presented with obstructive jaundice and features of malignant biliary stricture on ERCP and MRCP. Histopathology revealed myeloblasts, while peripheral blood and bone marrow did not reveal any evidence of leukemia.

Metrics

Metrics Loading ...

References

Avni B, Koren-Michowitz M. Myeloid sarcoma: current approach and therapeutic options. Ther Adv Hematol. 2011;2(5):309-16.

Cunningham I. Extramedullary sites of leukemia relapse after transplant. Leuk Lymphoma. 2006;47(9):1754-67.

Siraj F, Kaur M, Dalal V, Khanna A, Khan AA. Myeloid sarcoma: a report of four cases at unusual sites. Ger Med Sci. 2017;15:Doc03.

Meireles LC, Lagos AC, Marques I, Serejo F, Velosa J. Myeloid sarcoma of gastrointestinal tract: A rare cause of obstruction. Rev Esp Enferm Dig. 2015;107(5):326-7.

Modi G, Madabhavi I, Panchal H. Primary vaginal myeloid sarcoma: a rare case report and review of the literature. Case Rep Obstet Gynecol. 2015;2015:957490.

Garcia MG, Deavers MT, Knoblock RJ. Myeloid sarcoma involving the gynecologic tract: a report of 11 cases and review of the literature. Am J Clin Pathol. 2006;125(5):783-90.

Nguyen R, Sayar H. Primary Myeloid Sarcoma of the Prostate: A Case Report and Literature Review. Case Rep Hematol. 2018;2018:3604298.

Sahu KK, Tyagi R, Law AD. Myeloid Sarcoma: An Unusual Case of Mediastinal Mass and Malignant Pleural Effusion with Review of Literature. Indian J Hematol Blood Transfus. 2015;31(4):466-471.

Al-Quran SZ, Olivares A, Lin P, Stephens TW, Medeiros LJ, Abruzzo LV. Myeloid sarcoma of the urinary bladder and epididymis as a primary manifestation of acute myeloid leukemia with inv(16). Arch Pathol Lab Med. 2006;130(6):862-6.

Sahu KK, Kale SR, Siddiqui AD. Review on gall bladder myeloid sarcoma: a great masquerader. Chin Clin Oncol. 2020;9(3):37.

Norsworthy KJ, Bhatnagar B, Singh ZN, Gojo I. Myeloid Sarcoma of the Hepatobiliary System: A Case Series and Review of the Literature. Acta Haematol. 2016;135(4):241-51.

Menasce LP, Banerjee SS, Beckett E, Harris M. Extra-medullary myeloid tumour (granulocytic sarcoma) is often misdiagnosed: a study of 26 cases. Histopathology. 1999;34(5):391-8.

Lan TY, Lin DT, Tien HF, Yang RS, Chen CY, Wu K. Prognostic factors of treatment outcomes in patients with granulocytic sarcoma. Acta Haematol. 2009;122(4):238-246.

Audouin J, Comperat E, Le Tourneau A. Myeloid sarcoma: clinical and morphologic criteria useful for diagnosis. Int J Surg Pathol. 2003;11(4):271-82.

Pileri SA, Ascani S, Cox MC. Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia. 2007;21(2):340-50.

Almond LM, Charalampakis M, Ford SJ, Gourevitch D, Desai A. Myeloid Sarcoma: Presentation, Diagnosis, and Treatment. Clin Lymphoma Myeloma Leuk. 2017;17(5):263-7.

Imrie KR, Kovacs MJ, Selby D. Isolated chloroma: the effect of early antileukemic therapy. Ann Intern Med. 1995;123(5):351-3.