Prevalence of cardiovascular diseases and drug utilization review at secondary care hospital in South India
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20231699Keywords:
Cardiovascular diseases, Cardiovascular drugs, Prevalence, Drug utilization reviewAbstract
Background: To study prevalence of cardiovascular diseases and drug utilization review in patients with cardiovascular diseases.
Methods: This was a cross-sectional study conducted for about 6 months from December 2021 to February 2021 in a Secondary care hospital. Prescriptions of 167 patients with cardiovascular diseases were analysed. Patient Case files were used for extracting necessary data.
Results: The collected data was analyzed by MS-Excel (Counts and Percentages).Cardiovascular diseases were most common in the age group of 31-40 years (27.55%) followed by 51-60 years (24.49%) among male patients and in female patients, it was more common in the age group of 41-50 years (23.19%) followed by 51-60 years (21.74%). Most prevalent cardiovascular disease was found to be Hypertension (31%), followed by coronary artery disease (21%) and acute coronary syndrome (19%). Diabetes Mellitus (39%) and Hematological disorders (20%) are the most found co-morbidities along with cardiovascular diseases. Antiplatelet and antihypertensive were the most prescribed category of drugs. Of all Cardiovascular drugs, Aspirin (115 prescriptions) followed by Clopidogrel (100 prescriptions), Atorvastatin (73 prescriptions), Olmesartan (54 prescriptions) and Metoprolol (49 cases) were mostly prescribed. Common combinations of drugs prescribed are Aspirin + Clopidogrel + Atorvastatin (25%) followed by Aspirin + Clopidogrel (24%). Out of the total 658 drugs prescribed, 15.95% (105) were from Essential Drug List of India (2011). Of the total drugs prescribed, 15.95% (105) were from Essential Drug List of India.
Conclusions: The present study concluded that most of the drugs were prescribed rationally according to current guidelines. Combination therapy found to have an implication for the good cardiovascular outcome on long term follow-up.
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References
Cardiovascular diseases (CVDs). Available at https:// www.who.int/ en/ news-room/ fact-sheets/ detail/cardiovascular-diseases-(cvds). Accessed on 21 January 2023.
Cardiovascular diseases. Available at https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1. Accessed on 21 January 2023.
Treatment of a Heart Attack. Available at https:// www. heart.org/ en/ health-topics/ heart-attack/ treatment-of-a-heart-attack. Accessed on 21 March 2023.
Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study. Lancet. 1997;349:1498-504.
Bennett PN, Brown MJ. Prescribing, consumption, economics, and patient compliance. Clinical Epidemiology. 9th ed. Gurgaon: Elsevier India Private Limited. 2005;7:15-22.
Patil SB. Patient compliance. Int J Basic Clin Pharmacol. 2015;04(06):1100-3.
Veeramani H, Drug utilization pattern in cardiovascular diseases using WHO/INRUD prescribing indicators at cardiology opd of tertiary care hospitals in South India: a multicenter cross-sectional study. J Advances Med Med Res. 2020;32(09):107-20.
World Health Organisation. Rational use of Medicines. Available at http://www.who.int/medicines/areas/rational_use/en/index.html. Accessed on 22 May 21.
World Health Organisation. Drug Use Evaluation. Available at https:// www. who. int/ medicines/technical_briefing/tbs/11-PG_Drug-Use-Evaluation_final-08.pd. Accessed on 22 May 2021.
Blessy N. Prescribing pattern of cardiovascular drugs – a prospective observational study. Indian J Pharmacy Practice. 2017;10(04):287-92.
Vakade KP. A study of prescribing pattern of drugs in patients of cardiovascular emergencies at a tertiary care hospital of Western Maharashtra. Int J Res Med Sci. 2016;04(02):556-61.
Bhim R. Prevalence and drug utilization patterns of cardiovascular disease in a tertiary care hospital of bihar - a prospective and observational study. J Med Sci Clin Res. 2018;6(4):102-8.
Solanki N. Prescribing trends in cardiovascular conditions: a prospective cross-sectional study. J Basic Clin Pharm. 2019;10(02):87-9.
Zachariah TG. Drug utilization study in ischemic heart disease in a tertiary care hospital, Mangalore, India. Int J Basic Clin Pharmacol. 2017;6(7):1799-1805.
Bhavika D. Drug utilization study of anti-hypertensives drugs in a tertiary care hospital. Int J Basic Clin Pharmacol. 2016;5(4):1580-5.
How to Investigate Drug use in Health Facilities: Selected Drug use Indicators – EDM Research Series No. 007. WHO/DAP/93.1. Geneva: World Health Organization; 1993. World Health Organization. 1993.
Hirsh J, Warkenitin TE, Raschke R, Granger C, Ohman EM, Dale JE. Heparin and LMW heparin: Mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy and safety. Chest. 1998;114:4895–5105.
