A status report on glanders in Madhya Pradesh, India: a re-emerging zoonotic disease

Aanchal Bijlwan; Saurav Kumar; Yogesh S. Kaurav; Veena Sinha; Shailendra Singh

doi:10.18203/2394-6040.ijcmph20234148

Authors

Aanchal Bijlwan Department of Community Medicine, R D Gardi Medical College, Ujjain, Madhya Pradesh, India
Saurav Kumar Ministry of Health and Family Welfare, Bhopal, Madhya Pradesh, India
Yogesh S. Kaurav Directorate of Health Services, IDSP, DHS, Satpura Bhavan, Bhopal, Madhya Pradesh, India
Veena Sinha Directorate of Health Services, IDSP, DHS, Satpura Bhavan, Bhopal, Madhya Pradesh, India
Shailendra Singh Directorate of Health Services, IDSP, DHS, Satpura Bhavan, Bhopal, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20234148

Keywords:

Glanders, Re-emerging, Zoonotic, Madhya Pradesh, Public health

Abstract

Glanders, a zoonotic disease caused by Burkholderia mallei, has resurfaced as a significant health concern in Madhya Pradesh, India. This status report aims to provide a comprehensive overview of the current status of glanders, exploring its epidemiology, clinical implications, and socio-economic impact in the region. The data was collected in the state of Madhya Pradesh comprising of seven divisions and 52 districts with a population of 8.74 crores (projected data from census 2011). The data available in Interated Disease Surveillance Program (IDSP) cell of Directorate Health Services (Madhya Pradesh) was collected from the year 2017-2021. 17 positive cases were reported in six districts in the year 2018, and 11 cases were reported in six districts in the year 2019. Subsequently, in the year 2020, a total of 3 cases were reported from a single district, and 4 cases were reported from 4 districts in the year 2021. Early detection of disease in susceptible animals, strict quarantine measures, testing and safe destruction of infected carcasses, adequate compensation to animal owners, disinfection of infected premises, and public awareness of glanders and their zoonotic implications through veterinary extension services can be some of the effective countermeasures against glanders.

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References

McGilvray CD. The Transmission of Glanders from Horse to Man. Canad J Public Health. 1944;35(7):268-75.

Kettle ANB, Wernery U. Glanders and the risk for its introduction through the international movement of horses. Equine Vet J. 2016;48:654-8.

Van Zandt KE, Greer MT, Gelhaus HC. Glanders: An overview of infection in humans. Orphanet J Rare Dis. 2013;8:131.

Khakhum N, Tapia D, Torres AG. Burkholderia mallei and Glanders: Defense Against Biological Attacks. Springer, Cham. 2019;61;83.

Woods Lt. Col. JB. USAMRIID's Medical Management of Biological Casualties Handbook. Maryland, Fort Detrick. 2005.

Lehavi O, Aizenstien O, Katz LH, Hourvitz A. Glanders--a potential disease for biological warfare in humans and animals. Harefuah. 2002;141:88-91.

Verma AK, Saminathan M, Neha, Tiwari R, Dhama K, Singh SV. Glanders-A re-emerging zoonotic disease: A review. J Biolog Sci. 2014;14:38-51.

Yingst SL, Facemire P, Chuvala L, Norwood D, Wolcott M, Huzella L. Pathological findings and diagnostic implications of a rhesus macaque (Macacca mulatta) model of aerosol exposure to Burkholderia mallei (glanders). J Med Microbiol. 2015;64(6):646-53.

Malik P, Khurana SK, Dwivedi SK. Re-emergence of glanders in India - Report of Maharashtra state. Indian J Microbiol. 2010;50(3):345-8.

Misra VC, Kaushik RK, Dhingra PN, Satija KC. Emergence of glanders epidemic in civilian equines of northern India. J Remount Vet Corps. 1985;24:110-5.

Khan I, Wieler LH, Melzer F, Elschner MC, Muhammad G, Ali S, et al. Glanders in animals: a review on epidemiology, clinical presentation, diagnosis and countermeasures. Transbound Emerg Dis. 2013;;60(3):204-21.

Kumar G, Sero F, Kumar R. Glanders and Farcy Sero-Suerveillance in Uttar Pradesh: An Overview. J Animal Feed Sci Technol. 2020;8(1).

Nguyen HVN, Smith ME, Hayoun MA. Glanders and Melioidosis. In: StatPearls. Treasure Island (FL): StatPearls Publishing. 2022.

National Centre for Disease Control, Directorate General of Health Services. CD Alert: Glanders: A Public Health Concern. Available at: https://ncdc.gov.in/WriteReadData/linkimages/CDAlertGLANDERS427247804.pdf. Accessed on 09 September 2023.

Madhya Pradesh Population 2021/2022. Populationu.com. 2022. Available at: https://www. populationu.com/in/madhya-pradeshpopulation#: ~:text=Madhya%20Pradesh%20population%20in%202022,308%2C252%20sq%20km%20after%20Rajasthan. Accessed on 09 September 2023.

Santos Júnior ELD, Moura JCR, Protásio BKPF, Parente VAS, Veiga MHND. Clinical repercussions of Glanders (Burkholderia mallei infection) in a Brazilian child: a case report. Rev Soc Bras Med Trop. 2020;53:e20200054.

Van Zandt KE, Greer MT, Gelhaus HC. Glanders: an overview of infection in humans. Orphanet J Rare Dis. 2013;8(1):131.