Prevalence of hepatitis B and hepatitis C virus in haemodialysis patients
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20223271Keywords:
Hepatitis B, Hepatitis C, Virus, Prevalence, HaemodialysisAbstract
Hepatitis B (HBV) and hepatitis C virus (HCV) infections continue to remain a significant global health challenge due to its morbidity and mortality profile. Almost 600,000 annual deaths are associated with the hepatitis B and hepatitis C virus. Patients on haemodialysis are at increased chance of acquiring infections. Infection among haemodialysis patients can lengthen the hospital stay and contribute to further complications. Hepatitis B and hepatitis C virus infection is common among the haemodialysis patients. Cross-contamination to patients through environmental surfaces, supplies, equipment, multiple-dose drug bottles, and staff members are among the modes and causes of transmission of hepatis B and C virus infections in haemodialysis facilities. The purpose of this research is to review the available information about the prevalence of hepatitis B and hepatitis C virus in haemodialysis patients. Global prevalence for hepatitis C virus among haemodialysis units reported in studies ranged from 2.6% to 22.9% and 13.5% on average while for hepatitis B virus the prevalence is less than 10% while some studies report the prevalence ranging from 2-20%. Literature has variable prevalence for hepatitis B and C virus across the different geographical regions. The variation in prevalence is observed due to numerous risk factors contributing to the significant burden of the disease. Epidemiological data in recent times is lacking in literature and conduction of population-based surveys can be beneficial in generalizing the prevalence especially in gulf countries where limited studies are available.
References
Saraceni C, Birk J. A Review of Hepatitis B Virus and Hepatitis C Virus Immunopathogenesis. J Clin Translational Hepatol. 2021;9(3):409-18.
Lioussfi Z, Errami Z, Radoui A, et al. Viral hepatitis C and B among dialysis patients at the Rabat University Hospital: prevalence and risk factors. Saudi J Kidney Dis Transplant. 2014;25(3):672-9.
Joukar F, Besharati S, Mirpour H, Mansour-Ghanaei F. Hepatitis C and hepatitis B seroprevalence and associated risk factors in hemodialysis patients in Guilan province, north of Iran: HCV and HBV seroprevalence in hemodialysis patients. Hepatitis Monthly. 2011;11(3):178-81.
Elamin S, Abu-Aisha H. Prevention of hepatitis B virus and hepatitis C virus transmission in hemodialysis centers: review of current international recommendations. Arab J Nephrol Transplantation. 2011;4(1):35-47.
Winston A, Wurcel AG, Gordon C, Goyal N. Viral hepatitis in patients on hemodialysis. Seminars Dialysis. 2020;33(3):254-62.
Adane T, Getawa S. The prevalence and associated factors of hepatitis B and C virus in hemodialysis patients in Africa: A systematic review and meta-analysis. PloS one. 2021;16(6):e0251570.
Mahupe P, Molefe-Baikai OJ, Saleshando G, Rwegerera GM. Prevalence and risk factors for hepatitis b and c among end-stage renal disease patients on hemodialysis in Gaborone, Botswana. Nige J Clin Pract. 2021;24(1):81-8.
Rinonce HT, Yano Y, Utsumi T. Hepatitis B and C virus infection among hemodialysis patients in Yogyakarta, Indonesia: Prevalence and molecular evidence for nosocomial transmission. J Med Virol. 2013;85(8):1348-61.
Su Y, Yan R, Duan Z. Prevalence and risk factors of hepatitis C and B virus infections in hemodialysis patients and their spouses: a multicenter study in Beijing, China. Journal of medical virology. 2013;85(3):425-432.
Duong MC, Nguyen VTT, Otsu S, McLaws ML. Prevalence of hepatitis B and C virus infections in hemodialysis patients in Vietnam: A systematic review and meta-analysis. JGH open : an open access journal of gastroenterology and hepatology. 2020;4(1):29-38.
Shabbir U HW, Raza A. Seroprevalence of Hepatitis B Virus and Hepatitis C Virus in Patients Undergoing Maintenance Hemodialysis. Cureus. 2022;14(5).
Raina D, Rawat N, Pandita AK. Prevalence of Hepatitis B and Hepatitis C in Patients undergoing hemodialysis at a teaching hospital in Uttarakhand. J Family Med Pri Care. 2022;11(4).
Kalantari H, Ebadi S, Yaran M, Maracy MR, Shahshahan Z. Prevalence and risk factors of hepatitis B and C viruses among hemodialysis patients in Isfahan, Iran. Adv Biomed Res. 2014;3:73.
Alashek WA, McIntyre CW, Taal MW. Hepatitis B and C infection in haemodialysis patients in Libya: prevalence, incidence and risk factors. BMC Infect Dis. 2012;12(1):265.
Al Zabadi H, Rahal H, Fuqaha R. Hepatitis B and C prevalence among hemodialysis patients in the West Bank hospitals, Palestine. BMC Infect Dis. 2016;16:41.
Abou Rached A, El Khoury L, El Imad T, Geara AS, Jreijiry J, Ammar W. Incidence and prevalence of hepatitis B and hepatitis C viruses in hemodialysis patients in Lebanon. World J Nephrol. 2016;5(1):101-7.
Ashkani-Esfahani S, Alavian SM, Salehi-Marzijarani M. Prevalence of hepatitis C virus infection among hemodialysis patients in the Middle-East: A systematic review and meta-analysis. World J Gastroenterol. 2017;23(1):151-66.