Multi-center study to analyse outcome of integrated treatment approach in COVID-19 patients


  • Suraj Purushothaman Department of Critical Care, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India
  • Prasant Kumar Dhotre Department of Critical Care, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India
  • Kamlesh Prakash Vanarase Medical Officer, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India
  • Gajanan Kisan Jadhao Medical Officer, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India
  • Abhay Gyanchand Maurya Medical Officer, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India
  • Sanjay Mohanlal Gupta Medical Officer, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India
  • Vijaykumar Gawali Department of Medical Research and Education, Bhaktivedanta Hospital and Research Institute, Mira Road, Maharashtra, India



COVID-19, Limited resource setting, Minimal use of oxygen, Mortality, Patient outcome, Progesterone as immunomodulator, Treatment strategy


Background: This study presents the outcome of integrated treatment approach based on government mandated standard allopathic treatment along with alternatives in COVID-19 patients. The aim of our study was to investigate the outcome of treatment strategy, co-morbid status, recovery and mortality rate of COVID-19 patients at Bhaktivedanta Hospital and Research Institute.

Methods: Post ethics committee approval for multiple centers, data for 1049 COVID-19 patients (RTPCR confirmed cases) of all age groups and genders which were admitted in a dedicated covid hospital from March 2020 to November 2020 was analysed retrospectively.

Results: This study highlights the management of COVID-19 patients with an integrated approach. In our cohort with 36.7%, 44.70 %, 18.58% of mild, moderate and severe cases respectively, mortality rate was only 3.43% of total positive patients admitted at our hospital.

Conclusions: We emphasize that even in healthcare facilities with limited resource and poor infrastructure and lack of ICU facilities, clinical observation-based management can help to reduce mortality considerably. Unique features of our study include use of progesterone as an immune modulator, use of dual antiviral agents and use of age-related lower limit of oxygen saturation.


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How to Cite

Purushothaman, S., Dhotre, P. K., Vanarase, K. P., Jadhao, G. K., Maurya, A. G., Gupta, S. M., & Gawali, V. (2023). Multi-center study to analyse outcome of integrated treatment approach in COVID-19 patients. International Journal Of Community Medicine And Public Health, 10(2), 723–728.



Original Research Articles